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Orthodex Tablet is a combination medicine that helps in relieving pain. It works by blocking the release of certain chemical messengers that cause pain, inflammation, and fever in various conditions. It also blocks the transmission of pain signals to the brain to lower pain perception.

Written By Dr. Subita Alagh, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 25 Nov 2025 | 03:07 PM (IST)
₹51.3 MRP ₹56.7210% off 
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Orthodex Tablet image
Orthodex Tablet image

Product introduction

Orthodex Tablet should be taken with food. This will prevent you from getting an upset stomach. The dose will depend on what you are taking it for and how well it helps your symptoms. You should take it as advised by your doctor. Do not take more or use it for a longer duration than recommended by the doctor.

The most common side effects of this medicine include nausea, vomiting, diarrhea, sleepiness, dizziness, and increased liver enzymes. If any of these side effects bother you or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the side effects.

Before taking it, you should let your doctor know if you have a history of ulcer or bleeding in your stomach, high blood pressure, or have any trouble with your heart, kidneys, or liver. Let your doctor also know about all the other medicines you are taking because they may affect, or be affected by, this medicine.

Pregnant or breastfeeding women should consult their doctor before starting treatment. You should also avoid drinking alcohol while you are taking this medicine, as alcohol can cause excessive drowsiness.


Note: As per the Ministry of Health and Family Welfare, Orthodex Tablet is banned for children under 12 years of age.

Uses of Orthodex Tablet

Benefits of Orthodex Tablet

Pain relief
Orthodex Tablet effectively gives relief from muscle, joint, back pain, headache, toothache and menstrual pain. It also reduces fever associated with any painful conditions. Orthodex Tablet prevents the release of substances that increase pain and temperature and works quickly, usually within a few hours. This helps reduce discomfort and thus improve the quality of your life.

Side effects of Orthodex Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Orthodex
  • Nausea
  • Vomiting
  • Diarrhea
  • Sleepiness
  • Dizziness
  • Increased liver enzymes

How to use Orthodex Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Orthodex Tablet should be taken with or after food.

How Orthodex Tablet works

Orthodex Tablet is a combination of three medicines: Nimesulide, Paracetamol and Dextropropoxyphene which relieve pain and relax the muscles. Nimesulide is a non-steroidal antiinflammatory drug (NSAID) and Paracetamol is an antipyretic (fever reducer). They work by blocking the release of certain chemical messengers in the brain that cause pain and fever. Dextropropoxyphene is a opioid analgesic (pain reliever). It works by decreasing the perception of pain by blocking the transmission of pain signals to the brain.

Quick tips

  • Orthodex Tablet is used to treat various painful conditions.
  • Take it with food to prevent stomach upset.
  • Stick to simple meals and avoid spicy rich food in order to avoid feeling sick (nausea).
  • Drink plenty of water while taking this medicine.
  • Do not take indigestion remedies (antacids) within two hours of taking Orthodex Tablet.
  • Do not take it with any other pain medicine without asking your doctor first.
  • Inform your doctor if you are planning to have an operation (even a minor one, such as tooth extraction) since Orthodex Tablet increases the risk of bleeding.

Safety advice

Alcohol

Alcohol

UNSAFE
It is unsafe to consume alcohol with Orthodex Tablet
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Information regarding the use of Orthodex Tablet during pregnancy is not available. Please consult your doctor.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Information regarding the use of Orthodex Tablet during breastfeeding is not available. Please consult your doctor.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Orthodex Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Kidney

Kidney

CONSULT YOUR DOCTOR
There is limited data available on the use of Orthodex Tablet in patients with kidney disease. Please consult your doctor.
Liver

Liver

CONSULT YOUR DOCTOR
There is limited data available on the use of Orthodex Tablet in patients with liver disease.

Fact Box

Habit Forming

Yes

Therapeutic Class

PAIN ANALGESICS
100% genuine products
100% genuine products
Safe & secure payments
Safe & secure payments
No contact delivery
No contact delivery
Fully sanitized facilities
Fully sanitized facilities

User feedback

Twice A Day
60%
Thrice A Day
20%
Once A Day
20%
Pain relief
100%
Excellent
100%
Sleepiness
100%
With or without food
100%
Not Expensive
50%
Expensive
50%
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Psychotropics India Ltd
Address: Plot No -17, Sector – 20A, Faridabad, Haryana – 121001, India

Vendor Details

Country of origin: India
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