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MBA, MD Pharmacology
Last updated
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Orgalutran 0.25mg Injection

Prescription Required
SALT COMPOSITION
Storage
Store below 30°C

Product introduction

Orgalutran 0.25mg Injection is an anti-gonadotropin-releasing hormone medicine. It is used in the treatment of infertility in females. It restricts eggs to release directly and prevents premature ovulation.

Orgalutran 0.25mg Injection is injecting directly into the skin under the supervision of a doctor. Do not self administer the injection. Your doctor or nurse may help you to know the best way to inject the medicine at home. The dose and how often you take it depends on what you are taking it for. Your doctor will decide how much you need to improve your symptoms. You should take this medicine for as long as it is prescribed for you.

The most common side effects of this medicine include injection site reaction (redness, itching, and irritation), vaginal bleeding, and nausea. To overcome irritation at the injection site, use a different injection site every day to inject the medicine. If you experience dizziness, faint, abdominal pain, and vomiting after getting the injection, inform your doctor immediately.

Before taking this medicine, tell your doctor if you have ever had liver or kidney disease or if you are breastfeeding to a baby. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works.

Uses of Orgalutran Injection

Benefits of Orgalutran Injection

In Female infertility

Orgalutran 0.25mg Injection prevents release of premature eggs during a process called ovulation in females. This helps in normal development of an egg in a woman's ovary (female reproductive organ), and stimulates the release of a healthy, matured egg. This helps to treat infertility in women and increases the chance of a successful pregnancy. It is given as an injection by a doctor or nurse and should not be self-administered. You should use the medicine as prescribed for it to be effective.

Side effects of Orgalutran Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Orgalutran

  • Injection site reaction
  • Headache
  • Nausea
  • Ovarian hyperstimulation syndrome
  • Abdominal pain
  • Vaginal bleeding

How to use Orgalutran Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Orgalutran Injection works

In females undergoing treatment for infertility, sometimes premature ovulation can lead to the release of those eggs which are not ready for fertilization. Orgalutran 0.25mg Injection blocks the action of a natural hormone and prevents premature release of the eggs from the ovary.

Safety advice

Alcohol
CAUTION
Caution is advised when consuming alcohol with Orgalutran 0.25mg Injection. Please consult your doctor.
Pregnancy
UNSAFE
Orgalutran 0.25mg Injection is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Breast feeding
UNSAFE
Orgalutran 0.25mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
CONSULT YOUR DOCTOR
It is not known whether Orgalutran 0.25mg Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
CAUTION
Orgalutran 0.25mg Injection should be used with caution in patients with kidney disease. Dose adjustment of Orgalutran 0.25mg Injection may be needed. Please consult your doctor.
Use of Orgalutran 0.25mg Injection is not advised in patients with moderate to severe kidney disease patients.
Liver
CAUTION
Orgalutran 0.25mg Injection should be used with caution in patients with liver disease. Dose adjustment of Orgalutran 0.25mg Injection may be needed. Please consult your doctor.
Use of Orgalutran 0.25mg Injection is not advised in patients with moderate to severe liver disease patients.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine

Quick tips

  • Orgalutran 0.25mg Injection helps prevent premature ovulation in women undergoing assisted reproduction treatments such as IVF.
  • It is injected under the skin (subcutaneously), preferably of the upper leg.
  • Inform your doctor immediately if you get very dizzy, faint, vomit, or have diarrhea while using this medicine. These could be symptoms of ovarian hyperstimulation syndrome (OHSS).
  • Do not use this medicine if you are already pregnant or breastfeeding.

Fact Box

Chemical Class
Polypeptides
Habit Forming
No
Therapeutic Class
HORMONES
Action Class
GNRH antagonists

Patient concerns

arrow
My infertility in 5min my dots Plz my infertility problem
Dr. Sonu Balhara Ahlawat
Obstetrics and Gynaecology
cant understand ur problem
Infertility problem. Taking treatment since may13. Did all test, iui, laparoscopy. said it's unexplained infertility.
Dr. Megha Tuli
Obstetrics and Gynaecology
Hi PATIENT to 1mgd0ctors. Dorry to hear about your problem. Unexplained infertility is rising rapidly these days due to the high stress levels in our lives. I would suggest you continue taking treatment and I'm sure you will get a good news soon. All the best. Let me know if i can assist you in any way.
arrow

User feedback


FAQs

Q. What is Orgalutran 0.25mg Injection and what it is used for?

Orgalutran 0.25mg Injection is an injectable preparation, which contains the active substance Ganirelix. It is used in women undergoing certain fertility treatments. It acts by blocking the release of luteinizing hormone (LH), thus preventing the early release of eggs and giving them the time to grow properly.

Q. How and in what dose can it be used?

It is given as an injection, only at a hospital or clinic by a medical healthcare professional. The patient may be monitored regularly for the follicular development. The treatment duration depends on the ovarian response of the patient.

Q. Does Orgalutran 0.25mg Injection stop follicle growth?

No, Orgalutran 0.25mg Injection does not slow or stop follicle growth

Q. Does Orgalutran 0.25mg Injection stop/ prevent ovulation?

No, Orgalutran 0.25mg Injection does not stop or prevent ovulation. It reduces luteinizing hormone (LH) surge in women suffering from premature ovulation or undergoing a controlled ovarian stimulation for assisted reproduction technique (like IVF).

Q. What are the possible side effects associated with it?

The most common side effect is local site reaction (redness of skin with or without swelling). You may also experience headache or nausea. However, these effects are temporary. If these persist consult your doctor. In addition, conditions like ovarian hyperstimulation syndrome (OHSS), and multiple births or birth defect may also be associated with the use of this medicine.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Masters SB. Hypothalmic & Pituitary Hormones. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 655.
  2. EMEA. Ganirelix. [Accessed 03 Apr. 2019] (online) Available from:External Link
  3. Ganirelix. Ravensburg, Germany: Vetter Pharma-Fertigung GmbH & Co. [Accessed 03 Apr. 2019] (online) Available from:External Link

Marketer details

Name: Organon (India) Ltd
Address: Gala No-1C, Bldg No. -B3, City Link Warehouse Com, Mumbai Nashik Highway,Vadapa, Tal Bhiwandi, Distt Thane 421 302
Country of origin: India

NOT FOR SALE
We do not facilitate sale of this product at present

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