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Orblicef 2.5g Injection is used to treat severe bacterial infections. It kills bacteria by disrupting their cell walls and blocks bacterial enzymes that can make them resistant. It helps control infection, reduce symptoms, and support faster recovery.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 24 Aug 2026 | 01:03 AM (IST)
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General Information

Contains

Cefepime (2gm)+ Enmetazobactam (0.5gm)

Marketer

Orchid Healthcare Solutions

Storage

Store in a refrigerator (2 - 8°C). Do not freeze.
The content is shown in English
Orblicef 2.5g Injection image
Orblicef 2.5g Injection image
Orblicef 2.5g Injection image
Orblicef 2.5g Injection image
Orblicef 2.5g Injection image
Orblicef 2.5g Injection image

Product introduction

Orblicef 2.5g Injection is administered as an injection, typically by a healthcare professional, ensuring the correct dose reaches your bloodstream for optimal effect. Completing the full prescribed course is important, even if symptoms improve, to fully clear the infection and prevent resistance.


Common side effects of Orblicef 2.5g Injection include injection site reactions, a positive Coombs’ test, low phosphorus levels, elevated liver enzymes, prolonged blood clotting times, and skin rashes. Inform your doctor if any of these occur or persist.


Orblicef 2.5g Injection should be avoided by those who are allergic to any of its ingredients or other beta-lactam antibiotics, as severe hypersensitivity reactions may occur. Patients with a history of seizures or other central nervous system disorders should use it carefully, as high levels may increase the risk of neurotoxicity.


Caution is advised in patients with kidney impairment, since dose adjustment is needed to avoid drug accumulation and toxicity. Liver function should be monitored in those with preexisting hepatic disorders, as increases in liver enzymes may occur. 

Uses of Orblicef Injection

  • Treatment of Severe bacterial infections

Benefits of Orblicef Injection

Treatment of Severe bacterial infections
Bacterial infections occur when harmful bacteria multiply and cause illness. Orblicef 2.5g Injection helps control and eliminate these bacteria, reducing infection and related symptoms like fever, pain, and inflammation. It supports faster recovery and helps prevent the infection from spreading, promoting overall health.

Side effects of Orblicef Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Orblicef
  • Injection site reactions (pain, swelling, redness)
  • Positive Coombs test
  • Abnormal phosphorous level in blood
  • Increased liver enzymes
  • Blood clotting disorder
  • Skin rash

How to use Orblicef Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Orblicef Injection works

Orblicef 2.5g Injection composed of cefepime and enmetazobactam. Cefepime is a broad-spectrum antibiotic that kills bacteria by interfering with the formation of their cell walls, causing them to rupture and die. Enmetazobactam is a beta-lactamase inhibitor that prevents certain bacterial enzymes from breaking down cefepime, making the antibiotic more effective against resistant bacteria. Together, they help fight a wide range of bacterial infections by both killing bacteria and overcoming resistance mechanisms.

All substitutes for Orblicef 2.5g Injection

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

  • Always inform your doctor if you have a history of allergy to penicillins, cephalosporins, or carbapenems.
  • Patients with kidney problems may need dose adjustments. Never miss follow-up tests.
  • Report unusual symptoms like confusion, seizures, or persistent diarrhea immediately.
  • Do not take Orblicef 2.5g Injection for viral illnesses such as the flu or a cold.
  • If you are on blood thinners, let your doctor know, as clotting times may be affected.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Orblicef 2.5g Injection. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Orblicef 2.5g Injection during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CAUTION
Orblicef 2.5g Injection should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Orblicef 2.5g Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Kidney

Kidney

CAUTION
Orblicef 2.5g Injection should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Liver

Liver

CONSULT YOUR DOCTOR
There is limited data available on the use of Orblicef 2.5g Injection in patients with liver disease.
All

Frequently asked questions

It is used to treat serious bacterial infections, especially when resistance to standard antibiotics is suspected or confirmed.
It is usually given into a vein (IV) by a doctor or a nurse in a hospital or clinical setting.
No, completing the full course is important to fully clear the infection and prevent antibiotic resistance.
Inform your doctor immediately, as this could be a sign of an allergic reaction.
Yes, your doctor may check kidney function, liver enzymes, and blood tests during treatment to ensure safety.

Fact Box

Habit Forming

No

Therapeutic Class

ANTI INFECTIVES

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Orchid Healthcare Solutions
Address: 18232 Northwest 27th Avenue, Miami Gardens, Florida 33056, United States

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Orblicef 2.5g Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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