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Onco Bcg 40mg Injection is a medicine used for treatment of early-stage bladder cancer. It is recommended for people with early bladder cancer that has not yet reached the bladder muscle. It kills the cancer cells and reduces the risk of cancer coming back again (recur).

Written By Dr. Anuj Saini, MMST, MBBS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 09 Aug 2026 | 01:09 AM (IST)
₹988 MRP ₹1040.285% off 
 
 
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General Information

Contains

Bacillus Calmette-Guerin strain (40mg)

Marketer

Cipla Ltd

Storage

Store in a refrigerator (2 - 8°C). Do not freeze.
The content is shown in English
Onco Bcg 40mg Injection image
Onco Bcg 40mg Injection image

Product introduction

Onco Bcg 40mg Injection is administered by a healthcare professional. It is instilled directly into the bladder through the urethra. For it to be effective, you should complete the course of the vaccine. You should not discontinue even if you get better until the course is completed.

Some common side effects of this medicines include difficulty in urination, urinary tract infection, and fever. These are usually mild and go away with time. However, if they persist or get worse, you should let your doctor know.

Before receiving the vaccine, you should let your doctor if you have ever had an allergic reaction to any vaccine. Also tell your doctor if you have any problems with your heart, kidneys, or liver. Some other medicines may react with this vaccine, so let your doctor know of all the medication you are taking. Pregnant or breastfeeding should consult their doctors first before receiving this vaccine.

Uses of Onco Bcg Injection

Benefits of Onco Bcg Injection

Treatment of Early-stage bladder cancer
Onco Bcg 40mg Injection helps to treat early stage bladder cancer. It kills the cancer cells by stimulating the immune system of our body. It prevents progression of the disease to advanced stages of cancer and also reduces the chances of recurrence of the cancer. It is given as an injection by a doctor or nurse directly into your bladder through a catheter. It should not be self-administered.

Side effects of Onco Bcg Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Onco Bcg
  • Limited data available

How to use Onco Bcg Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Onco Bcg Injection works

Onco Bcg 40mg Injection is a type of weakened bacteria. It works by activating the cells in the immune system which helps destroy cancer cells lining the bladder.

Quick tips

  • Onco Bcg 40mg Injection helps treat bladder cancer and also prevents cancer from coming back after bladder surgery.
  • It is put into your bladder through a tube by a doctor or nurse.
  • Do not drink any liquid 4 hours before or 2 hours after you get this medicine.
  • You will be asked to urinate immediately before and 2 hours after Onco Bcg 40mg Injection is given to you.
  • Inform your doctor if you are also taking medicines for tuberculosis, other medications such as antibiotics or those that affect the immune system.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Onco Bcg 40mg Injection. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Onco Bcg 40mg Injection during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CAUTION
Onco Bcg 40mg Injection should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.
Driving

Driving

SAFE
Onco Bcg 40mg Injection does not usually affect your ability to drive.
Kidney

Kidney

CONSULT YOUR DOCTOR
There is limited data available on the use of Onco Bcg 40mg Injection in patients with kidney disease. Please consult your doctor.
Liver

Liver

CONSULT YOUR DOCTOR
There is limited data available on the use of Onco Bcg 40mg Injection in patients with liver disease.
All

Frequently asked questions

Onco Bcg 40mg Injection is a medicine used to treat early stage bladder cancer. It is made from a weakened strain of Mycobacterium bovis, a vaccine for tuberculosis. Onco Bcg 40mg Injection stimulates the immune system to attack cancer cells and this stops the cancer from growing as well as spreading to other unaffected parts.
Onco Bcg 40mg Injection can cause side effects like difficulty in urination, urinary tract infection, and fever. It also commonly causes a burning feeling in the bladder, the need to urinate often, and even blood in the urine.
Usually, you may have a fever as one of the common side effects of Onco Bcg 40mg Injection. But if the fever is prolonged with a temperature of or above 101 degrees, or if you have chills, rash, prolonged cough, specific joint pain, or if any of these symptoms last longer than 48 hours, then you should contact your doctor immediately. Your doctor may prescribe some medications to relieve these side effects and may also suggest ways to cope up with them.
Yes, causes some irritation to the bladder and may cause bleeding that may give your urine a reddish color. Drink as much fluids as you can to keep your urine clear and to prevent blood clots from forming in the bladder. Usually, this bleeding resolves after sometime. But, if it does not or if it bothers you, consult your doctor.
No, one should refrain from having unprotected sexual intercourse while on treatment with Onco Bcg 40mg Injection. In fact, men must wear a condom for the entire six-week treatment and women must avoid any vaginal contact for an additional six weeks after treatment too. This is to ensure safety of the other partner, because Onco Bcg 40mg Injection does not contain dead but weakened bacteria. So, it may affect the unaffected individuals and therefore is advised not to indulge in sexual contact.
Onco Bcg 40mg Injection is a medicine used to treat early stage bladder cancer. It is made from a weakened strain of Mycobacterium bovis, a vaccine for tuberculosis. Onco Bcg 40mg Injection stimulates the immune system to attack cancer cells and this stops the cancer from growing as well as spreading to other unaffected parts.
Onco Bcg 40mg Injection can cause side effects like difficulty in urination, urinary tract infection, and fever. It also commonly causes a burning feeling in the bladder, the need to urinate often, and even blood in the urine.
Usually, you may have a fever as one of the common side effects of Onco Bcg 40mg Injection. But if the fever is prolonged with a temperature of or above 101 degrees, or if you have chills, rash, prolonged cough, specific joint pain, or if any of these symptoms last longer than 48 hours, then you should contact your doctor immediately. Your doctor may prescribe some medications to relieve these side effects and may also suggest ways to cope up with them.
Yes, causes some irritation to the bladder and may cause bleeding that may give your urine a reddish color. Drink as much fluids as you can to keep your urine clear and to prevent blood clots from forming in the bladder. Usually, this bleeding resolves after sometime. But, if it does not or if it bothers you, consult your doctor.
No, one should refrain from having unprotected sexual intercourse while on treatment with Onco Bcg 40mg Injection. In fact, men must wear a condom for the entire six-week treatment and women must avoid any vaginal contact for an additional six weeks after treatment too. This is to ensure safety of the other partner, because Onco Bcg 40mg Injection does not contain dead but weakened bacteria. So, it may affect the unaffected individuals and therefore is advised not to indulge in sexual contact.

Fact Box

Chemical Class

Biological extracts

Habit Forming

No

Therapeutic Class

VACCINES

Action Class

Live Attenuated Vaccines

References

  1. Sinha A, Singh S. Immunization and Immunodeficiency. In: Paul VK, Bagga A, editors. Ghai Essential Pediatrics. 8th ed. New Delhi: CBS Publisher's & Distributors Pvt Ltd.; 2013. pp. 190-91.
  2. Serum Institute of India. Bacillus Calmette-Guerin strain. [Accessed 04 Apr. 2019] (online) Available from:
  3. Serum Institute of India. ONCO-BCG (BCG Live) [Product Description]. [Accessed 19 Oct. 2023] (online) Available from:
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User feedback

Once A Week
43%
Once A Month
23%
Once A Day
20%
Twice A Month
10%
Twice A Week
3%
Others
75%
Tuberculosis (TB)
25%
Excellent
81%
Average
14%
Poor
6%
No Side Effect
62%
Fever
12%
Difficulty in urination
12%
Frequent urge to urinate
12%
With or without food
50%
Empty stomach
33%
With food
17%
Average
58%
Not Expensive
21%
Expensive
21%
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Cipla Ltd
Address: Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013

Vendor Details

Country of origin: India
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