ON-D-Rab Tablet

Written By Dr. Lipika Khurana, PGDHHM, BDS

Reviewed By Dr. Mekhala Chandra, MD, MBBS

Last updated on 22 Dec 2025 | 11:46 AM (IST)

ON-D-Rab Tablet is a combinational medicine commonly used to control nausea and vomiting due to certain medical conditions like stomach upset. It is also used to treat heartburn, acid reflux and problems in your food pipe.

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Renvorab-ON Tablet

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ON-D-Rab Tablet

strip of 10 tablets

₹95.2

~~₹107.81~~

Same composition

Renvorab-ON Tablet

strip of 10 tablets

Ondansetron (4mg) + Rabeprazole (20mg)

by Leeford Healthcare Ltd

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₹91.5

₹7.78 per tablet

₹77.8

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General Information

Contains

Ondansetron (4mg)+ Rabeprazole (20mg)

Marketer

Elliott Labs

Storage

Store below 30°C

The content is shown in English

Product introduction

ON-D-Rab Tablet can be taken with or without food. How much you need, and how often you take it, will depend on what you are being treated for. Follow the advice of your doctor. You should keep taking it regularly to prevent problems from happening in the future. You may be able to help improve your symptoms by eating smaller meals more often and avoiding spicy or fatty foods.

Most people who take it do not have any side effects, but the most common include headache, constipation and diarrhea. If you do get a side effect, it is usually mild and will go away when you stop taking this medicine or as you adjust to it. Consult your doctor if any of these side effects bother you or do not go away.

Before taking it, you should tell your doctor if you have any kidney or liver problems. This may affect the dose or suitability of this medicine. Also, tell your doctor what other medicines you are taking as some may affect, or be affected by, this medicine. If you are pregnant or breastfeeding, ask advice from your doctor.

Uses of ON-D-Rab Tablet

Benefits of ON-D-Rab Tablet

Nausea
ON-D-Rab Tablet blocks the action of chemicals in the body that can make you feel or be sick. This medicine helps you feel better and at ease. It is given as an injection by a doctor and you should follow the doctor’s instructions carefully to get the most benefit from this medicine.

Gastroesophageal reflux disease (Acid reflux)
Gastroesophageal reflux disease (GERD) is a chronic (long-term) condition which is like having heartburn consistently rather than just occasionally. It happens because a muscle above your stomach relaxes too much and allows stomach contents to come back up into your esophagus and mouth. ON-D-Rab Tablet reduces the amount of acid your stomach makes and relieves the pain associated with heartburn and acid reflux. You should take it exactly as it is prescribed for it to be effective.

Some simple lifestyle changes can help reduce the symptoms of GERD. Think about what foods trigger heartburn and try to avoid them; eat smaller, more frequent meals; try to lose weight if you are overweight and try to find ways to relax. Do not eat within 3-4 hours of going to bed.

Side effects of ON-D-Rab Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of ON-D-Rab

Nausea
Vomiting
Pain
Sore throat
Infection
Abdominal pain
Headache
Constipation
Fatigue
Diarrhea

How to use ON-D-Rab Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. ON-D-Rab Tablet may be taken with or without food.

How ON-D-Rab Tablet works

ON-D-Rab Tablet is a combination of two medicines: Ondansetron and Rabeprazole. Ondansetron is an antiemetic medication. It works by blocking the action of a chemical messenger (serotonin) in the brain that may cause nausea and vomiting. Rabeprazole is a proton pump inhibitor (PPI) which works by reducing the amount of acid in the stomach which helps in the relief of acid-related indigestion and heartburn.

All substitutes for ON-D-Rab Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

ON-D-Rab Tablet is used to give relief from nausea, vomiting as well as acidity, heartburn and other discomfort associated with acid reflux and peptic ulcer disease.
It is advisable to take your doses about half an hour before meals.
If you vomit within one hour of taking a dose, take another dose.
Avoid taking soft drinks, citrus fruits like orange and lemon, which can irritate the stomach and increase acid secretion.
Incorporate the following lifestyle changes in order to prevent acidity:
1. Make sure you eat regular meals and drink plenty of water.
2. Avoid spicy and fatty fried food.
3. Lose weight if you are obese.
4. If you are a smoker, consider giving up.
5. Don't drink too much alcohol.
6. Do not go to bed immediately after taking a meal. Sit in a relaxed position for sometimes for better digestion.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with ON-D-Rab Tablet

Pregnancy

CONSULT YOUR DOCTOR

Information regarding the use of ON-D-Rab Tablet during pregnancy is not available. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of ON-D-Rab Tablet during breastfeeding is not available. Please consult your doctor.

Driving

CONSULT YOUR DOCTOR

It is not known whether ON-D-Rab Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.

Kidney

CONSULT YOUR DOCTOR

There is limited data available on the use of ON-D-Rab Tablet in patients with kidney disease. Please consult your doctor.

Liver

CONSULT YOUR DOCTOR

There is limited data available on the use of ON-D-Rab Tablet in patients with liver disease.

Frequently asked questions

What is ON-D-Rab Tablet used for?

ON-D-Rab Tablet is used to relieve nausea and vomiting caused by conditions such as an upset stomach. It is also helpful in treating heartburn, acid reflux, and other problems related to the food pipe (esophagus).

Is ON-D-Rab Tablet used for GERD or ulcers when I also feel queasy or vomit?

Yes, ON-D-Rab Tablet supports reflux/ulcer care while also calming nausea, which can make it easier to keep food and medicines in stomach and not vomit out.

I get morning heartburn and feel sick after meals. Can ON-D-Rab Tablet help?

Many patients take ON-D-Rab Tablet when reflux‑related nausea is worst around meals. Your doctor will tailor the timing and duration of your routine.

Will ON-D-Rab Tablet help protect my stomach while I am on other treatments that upset it?

ON-D-Rab Tablet is commonly used when treatments irritate the stomach, combining nausea relief with acid reduction to improve comfort and adherence.

How soon might day‑to‑day symptoms start improving during ON-D-Rab Tablet treatment?

People often notice a calmer stomach and reduced queasiness within a day or two of using ON-D-Rab Tablet. Full benefit for reflux/ulcer symptoms builds over days to weeks as your plan continues.

Can I keep using my usual reflux lifestyle steps with ON-D-Rab Tablet?

Yes. Small regular meals, avoiding trigger foods, and elevating the head of the bed complement the ON-D-Rab Tablet and often improve results further.

What if my nausea or heartburn does not settle after a couple of weeks of using ON-D-Rab Tablet?

If your nausea or heartburn doesn’t improve after using ON-D-Rab Tablet for a couple of weeks, inform your doctor. Share details such as when the symptoms occur, what triggers them, and how severe they are. Your doctor may adjust the dose or timing of your medicine, or check for other possible causes like infection, bile reflux, or side effects from other medications.

Fact Box

Habit Forming

Therapeutic Class

GASTRO INTESTINAL

References

Sharkey KA, MacNaughton WK. Gastrointestinal Motility and Water Flux, Emesis, and Biliary and Pancreatic Disease. In: Brunton LL, Hilal-Dandan R, Knollmann BC (Editors). Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 13th ed. New York, NY: McGraw-Hill Education; 2018. pp. 922-944.
Hoogerwerf WA, Pasricha PJ. Pharmacotherapy of Gastric Acidity, Peptic Ulcers, and Gastroesophageal Reflux Disease. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. pp. 967-981.
McQuaid KR. Drugs Used in the Treatment of Gastrointestinal Diseases. In: Katzung BG, Masters SB, Trevor AJ (Editors). Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 1067-1101.
Rabeprazole and ondansetron. Pune, Maharashtra: Epione Pharmaceuticals Pvt. Ltd.; [Accessed 05/11/2025] (online) Available from:

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Elliott Labs
Address: Elliott Labs Pvt. Ltd. 596-597, Udyog Vihar, – 5, Gurugram -122016 (Haryana)a

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Provide right medicines

Prescriptions are complex documents. We proof read and recheck at various steps to provide you the right medication in the correct form and dose

In accordance with the law

Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945

ON-D-Rab Tablet

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General Information

Contains

Marketer

Storage

Product introduction

Uses of ON-D-Rab Tablet

Benefits of ON-D-Rab Tablet

Side effects of ON-D-Rab Tablet

How to use ON-D-Rab Tablet

How ON-D-Rab Tablet works

All substitutes for ON-D-Rab Tablet

Rebozen ON 4mg/20mg Tablet

Rafron Total Tablet

Renvorab-ON Tablet

Rabopep O Tablet

Rabnor O 4mg/20mg Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

What is ON-D-Rab Tablet used for?

Is ON-D-Rab Tablet used for GERD or ulcers when I also feel queasy or vomit?

I get morning heartburn and feel sick after meals. Can ON-D-Rab Tablet help?

Will ON-D-Rab Tablet help protect my stomach while I am on other treatments that upset it?

How soon might day‑to‑day symptoms start improving during ON-D-Rab Tablet treatment?

Can I keep using my usual reflux lifestyle steps with ON-D-Rab Tablet?

What if my nausea or heartburn does not settle after a couple of weeks of using ON-D-Rab Tablet?

Fact Box

Habit Forming

Therapeutic Class

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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