
Ofsmith M Syrup
Written By Dr. Swati Mishra, BDS
Reviewed By Dr. Rajeev Sharma, MBA, MBBS
Last updated on 25 Nov 2025 | 03:07 PM (IST)
Ofsmith M Syrup is given to children for the treatment of bacterial infections of the teeth, lungs, gastrointestinal tract, urinary tract, and genital tract. This medicine is also given as an empirical antibiotic for infected diarrhea mixed with blood and serious infections like peritonitis.
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General Information
The content is shown in English



Your child’s medicine at a glance
Give Ofsmith M Syrup to your child orally, preferably at a fixed time, either before or after meals. In case your child develops a stomach upset, prefer giving it with meals. Generally, this medicine is prescribed to be given two times a day, in the morning and evening. If your child vomits within 30 minutes of intake, repeat the same dose but do not double the dose if it is time for the next dose. Never change the dose, time, and way prescribed by the doctor since these depend upon the type and severity of the infection, your child’s age, and body weight.
In some cases, this medicine may cause some minor and temporary side effects, including nausea, vomiting, weight loss, metallic taste, headache, loss of appetite, abdominal cramps, and mild skin rash. These side effects are temporary and recede when your child gets used to the medicine. In case the side effects persist or start bothering your child, consult your child’s doctor without any delay.
Narrate your child’s complete medical history to your child’s doctor, including any previous episode of allergy, heart problem, liver impairment, and kidney malfunction. This information is critical for dose alterations and for planning your child’s overall treatment.
In some cases, this medicine may cause some minor and temporary side effects, including nausea, vomiting, weight loss, metallic taste, headache, loss of appetite, abdominal cramps, and mild skin rash. These side effects are temporary and recede when your child gets used to the medicine. In case the side effects persist or start bothering your child, consult your child’s doctor without any delay.
Narrate your child’s complete medical history to your child’s doctor, including any previous episode of allergy, heart problem, liver impairment, and kidney malfunction. This information is critical for dose alterations and for planning your child’s overall treatment.
Uses of Ofsmith M Syrup in children
Benefits of Ofsmith M Syrup for your child
Treatment of Bacterial infections
Ofsmith M Syrup is an antibiotic medicine given to children for the treatment of a wide range of bacterial infections such as tooth abscess, gum infection, pneumonia, diarrhea, dysentery, peritonitis, burning sensation while passing urine, and certain genital tract infections. This medicine inhibits the growth of infection-causing bacteria by stopping it from multiplying. You may start seeing an improvement in the infection within 3 to 5 days of regular dosing. But, you must still finish the full course of the medicine and never stop it abruptly by yourself as that may worsen your child’s condition or cause infection recurrence.
Ofsmith M Syrup is an antibiotic medicine given to children for the treatment of a wide range of bacterial infections such as tooth abscess, gum infection, pneumonia, diarrhea, dysentery, peritonitis, burning sensation while passing urine, and certain genital tract infections. This medicine inhibits the growth of infection-causing bacteria by stopping it from multiplying. You may start seeing an improvement in the infection within 3 to 5 days of regular dosing. But, you must still finish the full course of the medicine and never stop it abruptly by yourself as that may worsen your child’s condition or cause infection recurrence.
Side effects of Ofsmith M Syrup in children
Ofsmith M Syrup does not pose serious side effects and is well-tolerated by children. In case the side effects do occur, they’re likely to subside once the body adapts to the medicine. Consult your child’s doctor if these side effects persist or bother your child. The most common side effects include-
Common side effects of Ofsmith M
- Vomiting
- Nausea
- Weight loss
- Abdominal pain
- Headache
- Diarrhea
- Loss of appetite
- Dizziness
- Insomnia (difficulty in sleeping)
- Metallic taste
- Urine discoloration
How can I give Ofsmith M Syrup to my child?
Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Ofsmith M Syrup may be taken with or without food.
How Ofsmith M Syrup works
Ofsmith M Syrup is a combination of three active ingredients. While two of its ingredients, namely ofloxacin and metronidazole are antibiotics, simethicone is a gas-absorbing agent that improves gastric tolerability of the combination. The antibiotic ingredients interfere with the genetic material of bacteria by impairing its DNA. This kills the infection-causing bacteria, preventing its growth and stopping the infection. On the other hand, Simethicone binds with the gas bubbles produced as a result of the other two ingredients or as a result of some other problem. By doing so, it aids in the removal of gases and provides relief in stomach pain and bloating.
All substitutes for Ofsmith M Syrup
For information purposes only. Consult a doctor before taking any medicine.
Quick tips
- Diarrhea is a common side effect of this medicine. If it occurs, make sure your child drinks plenty of water.
- Your child may have an altered taste or furry tongue (coating of Ofsmith M Syrup on tongue) after taking Ofsmith M Syrup. Eating citrus fruit or sipping plenty of water or fruit juice may help.
- Do not give any calcium, magnesium, iron, vitamin, or antacid within 2 hours of taking Ofsmith M Syrup as these can affect the absorption of the medicine.
- Never use this medicine for the common cold and flu as they are caused by viruses and Ofsmith M Syrup treats only bacterial infections.
- Discontinue Ofsmith M Syrup and inform the doctor immediately if your child develops a rash, itchy skin, swelling of face and mouth, or has difficulty in breathing.
- Only give Ofsmith M Syrup to your child for their current infection. Never save medicine for future illnesses.
Safety advice

Kidney
CAUTION
Ofsmith M Syrup should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver
CAUTION
Ofsmith M Syrup should be used with caution in patients with severe liver disease. Dose adjustment may be needed.
Frequently asked questions
You must tell the doctor if your child is suffering from heart disease, seizures, psychiatric disorders, diabetes, photoallergy (allergy from sunlight), neuromuscular disorders, rheumatoid arthritis, or genetic disorders involving blood vessels. This is because there is a possibility that Ofsmith M Syrup may aggravate these conditions and result in complications.
No, do not give Ofsmith M Syrup with cough and cold medicines. The reason being, one of the ingredients present in Ofsmith M Syrup can interact with alcohol-containing medicines like cough syrups and can lead to disulfiram reaction, causing nausea, vomiting, flushing, dizziness, etc.
An extra dose of Ofsmith M Syrup is unlikely to harm. However, if you think you have given too much to your child, immediately speak to a doctor. Overdose may cause unwanted side effects such as seizures, tremors, severe headache, sudden weakness, blood cell abnormalities, and rapid and irregular heartbeat. Rush to your child’s doctor if you notice any of these symptoms.
It could mean that Ofsmith M Syrup is unable to kill the infection-causing bacteria. In such a case, visit your child’s doctor who may prescribe some other antibiotic that has a higher efficacy against the disease-causing bacteria. Remember, that sometimes, such antibiotics may have to be given by IV route (intravenous injection) in the hospital.
Ofsmith M Syrup can sometimes interact with other medicines or substances. Tell your doctor about any other medicines your child is taking before starting Ofsmith M Syrup. Also, check with your child’s doctor before giving any medicine to your child.
Store Ofsmith M Syrup at room temperature, in a dry place, away from direct heat and light. Children may accidentally consume medicines if they find them while playing around. So, make sure that all the medicines are kept away from their reach and sight.
Antibiotics usually do not interfere with the ingredients in vaccines or cause a bad reaction in a child who has just been vaccinated. However, children taking antibiotics should not get vaccinated until they recover from the illness. As soon as your child feels better, the vaccine can be given.
Ofsmith M Syrup contains active ingredient metronidazole, which causes red-brown urine. It is not pathogenic but a side effect. It subsides once the medicine is stopped after the completion of the treatment.
Fact Box
Habit Forming
No
Therapeutic Class
GASTRO INTESTINAL
Related lab tests
References
- Metronidazole [FDA Label]. Chicago, IL: G.D. Searle LLC; 2003. [Accessed 19 Jan. 2021] (online) Available from:
- University of Michigan: C.S. Mott Children’s Hospital. Metronidazole. [Accessed 20 Jan. 2020] (online) Available from:
- University of Michigan: C.S. Mott Children’s Hospital. Ofloxacin. [Accessed 20 Jan. 2020] (online) Available from
- Memorial Sloan Kettering Cancer Center. Ofloxacin (Systemic): Pediatric Medication. [Accessed 20 Jan. 2020] (online) Available from:
- University of Michigan: C.S. Mott Children’s Hospital. Simethicone. [Accessed 20 Jan. 2020] (online) Available from:
- Memorial Sloan Kettering Cancer Center. Simethicone. [Accessed 20 Jan. 2020] (online) Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
Marketer details
Name: Nusmith Pharma Pvt. Ltd
Address: 10, S.D.P.S. Complex, Kalka – 133302 ( Panchkula) HR
Address: 10, S.D.P.S. Complex, Kalka – 133302 ( Panchkula) HR
Vendor Details
Country of origin: India
Lab tests offered by us
- CBC (Complete Blood Count)
- FBS (Fasting Blood Sugar)
- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- PPBS (Postprandial Blood Sugar)
- Lipid Profile
- Vitamin D (25-Hydroxy)
- Urine R/M (Urine Routine & Microscopy)
- Coronavirus Covid -19 test- RT PCR
- LFT (Liver Function Test)
- KFT (Kidney Function Test)
- TSH (Thyroid Stimulating Hormone) Ultrasensitive
- ESR (Erythrocyte Sedimentation Rate)
- Uric Acid, Serum
- Vitamin B12
- CRP (C-Reactive Protein), Quantitative
- Urine C/S (Urine Culture and Sensitivity)
- Serum Electrolytes
- Serum Calcium
- Serum Creatinine
- Diabetes Screening (HbA1C & Fasting Sugar)
- KFT with Electrolytes (Kidney Function Test with Electrolytes)
- Cholesterol - Total
- Hb (Hemoglobin)
- Complete Hemogram (CBC & ESR)
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