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Nucoxia SP Tablet is a pain relieving medicine. It is used to reduce pain and inflammation in conditions like rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis. It may also be used to relieve muscle pain, back pain, toothache, or pain in the ear and throat.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 27 Sep 2025 | 12:45 PM (IST)
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General Information

Contains

Etoricoxib (60mg)+ Serratiopeptidase (10mg)

Marketer

Zydus Cadila

Storage

Store below 30°C
The content is shown in English
Nucoxia SP Tablet image
Nucoxia SP Tablet image
Nucoxia SP Tablet image
Nucoxia SP Tablet image
Nucoxia SP Tablet image

Product introduction

Nucoxia SP Tablet can be taken with or without food. You should take it regularly as advised by your doctor. Your doctor may change the dose and time between doses according to your pain level and your needs. Do not take more or use it for a longer duration than recommended by your doctor.

Some of the common side effects of this medicine include diarrhea, stomach pain, indigestion, flatulence, swelling of hands and feet, and flu-like symptoms. If any of these side effects bother you or do not go away with time, you should let your doctor know. Your doctor may help with ways to reduce or prevent these side effects by prescribing an alternative medicine or adjusting the dose.

The medicine may not be suitable for everybody. Before taking it, let your doctor know if you have any problems with your heart, kidneys, liver, or have stomach ulcers. To make sure it is safe for you, let your doctor know about all the other medicines you are taking. Pregnant and breastfeeding mothers should first consult their doctors before using this medicine.

Uses of Nucoxia SP Tablet

Benefits of Nucoxia SP Tablet

Pain relief
Nucoxia SP Tablet relieves pain, reduce swelling and ease inflammation in conditions like rheumatoid arthritis, osteoarthritis, ankylosing spondolytis and gout. It is also used for the short term treatment of moderate pain after dental surgery. This medicine also contains an active ingredient called Serratiopeptidase, which is an enzyme that promotes the overall healing process and speeds up recovery.

Side effects of Nucoxia SP Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Nucoxia SP
  • Diarrhea
  • Stomach pain
  • Indigestion
  • Flatulence
  • Swelling of hands
  • Feet swelling
  • Flu-like symptoms

How to use Nucoxia SP Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Nucoxia SP Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Nucoxia SP Tablet works

Nucoxia SP Tablet is a combination of two medicines: Etoricoxib and Serratiopeptidase. Etoricoxib is a non-steroidal anti-inflammatory drug (NSAID) which works by blocking the release of certain chemical messengers that cause pain and inflammation (redness and swelling). Serratiopeptidase is an enzyme which works by breaking down abnormal proteins at the site of inflammation, and promotes healing.

All substitutes for Nucoxia SP Tablet

For information purposes only. Consult a doctor before taking any medicine.

Xircox SP Tablet

by HBC Lifesciences Pvt Ltd
₹11.1/tablet
36% cheaper
<h3 class=bodySemiBold>Xircox SP Tablet</h3>

Quick tips

  • You have been prescribed Nucoxia SP Tablet to get relief from pain and inflammation.
  • You can take the tablet either with or without food, although the tablets may work more quickly if they are taken without food.
  • During long-term treatment, your doctor may want to take regular blood tests to monitor your liver function.
  • If you have asthma, symptoms such as wheeze or breathlessness can be made worse by Nucoxia SP Tablet. If this happens to you, see your doctor as soon as possible.

Safety advice

Alcohol

Alcohol

UNSAFE
It is unsafe to consume alcohol with Nucoxia SP Tablet.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Nucoxia SP Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Information regarding the use of Nucoxia SP Tablet during breastfeeding is not available. Please consult your doctor.
Driving

Driving

UNSAFE
Nucoxia SP Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

CAUTION
Nucoxia SP Tablet should be used with caution in patients with kidney disease. Dose adjustment of Nucoxia SP Tablet may be needed. Please consult your doctor.
Use of Nucoxia SP Tablet is not recommended in patients with severe kidney disease.
Liver

Liver

CAUTION
Nucoxia SP Tablet should be used with caution in patients with liver disease. Dose adjustment of Nucoxia SP Tablet may be needed. Please consult your doctor.
Use of Nucoxia SP Tablet is not recommended in patients with severe liver disease.

Frequently asked questions

Nucoxia SP Tablet is a pain-relieving medicine. It is used to reduce pain and inflammation in conditions like rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis. It may also be used to relieve muscle pain, back pain, toothache, or pain in the ear and throat.
Individuals should avoid taking Nucoxia SP Tablet if they have allergies to NSAIDs, active stomach ulcers or bleeding, severe liver or kidney problems, uncontrolled high blood pressure, heart failure, or a history of heart attack or stroke.
Nucoxia SP Tablet may increase the risk of heart attack, stroke, and high blood pressure, especially if taken long-term or if you have pre-existing heart conditions.
Nucoxia SP Tablet can affect liver and kidney function, so regular monitoring may be needed, especially in patients with existing liver or kidney disease.
The exact time Nucoxia SP Tablet takes to show its effect is not known. However, pain relief usually starts within a few hours, but full benefit may take several days. Follow your doctor’s advice and complete the prescribed course.

Fact Box

Habit Forming

No

Therapeutic Class

PAIN ANALGESICS

References

  1. Etoricoxib. Haarlem, The Netherlands: Merck Sharp & Dohme B.V.; 2018. [Accessed 23 Jan. 2019] (online) Available from:
  2. Bhagat S, Agarwal M, Roy V. Serratiopeptidase: A systematic review of the existing evidence. Int J Surg. 2013;11(3):209-17. [Accessed 02 Apr. 2019] (online) Available from:
  3. Etoricoxib. Hoddesdon, Hertfordshire: Merck Sharp & Dohme Limited; 2016. [Accessed 02 Apr. 2019] (online) Available from:
  4. PubChem. Serratiopeptidase. [Accessed 02 Apr. 2019] (online) Available from:
  5. ScienceDirect. Etoricoxib. [Accessed 02 Apr. 2019] (online) Available from:
  6. ScienceDirect. Serratiopeptidase. [Accessed 02 Apr. 2019] (online) Available from:
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User feedback

Twice A Day
100%
Pain relief
100%
Excellent
58%
Average
42%
No Side Effect
67%
Stomach pain
33%
With food
100%
Expensive
56%
Average
22%
Not Expensive
22%
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Zydus Cadila
Address: Zydus Tower, Satellite Cross Roads,Ahmedabad – 380015 Gujarat, India.

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Nucoxia SP Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's â„ž and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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