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Norflam Plus Tablet

Written By Dr. Syeda Aafia, MBA, BDS
Reviewed By Dr. Lalit Kanodia, MBA, MD Pharmacology
Last updated on 21 Sep 2025 | 05:41 PM (IST)
Norflam Plus Tablet is a pain-relieving medicine. It is used to reduce pain and inflammation in conditions like rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis. It may also be used to relieve muscle pain, back pain, toothache, or pain in the ear and throat.
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General Information

Contains

Ibuprofen (400mg)+ Paracetamol (325mg)+ Caffeine (30mg)

Marketer

Brussels Laboratories Pvt Ltd

Storage

Store below 30°C
The content is shown in English
Norflam Plus Tablet image
Norflam Plus Tablet image

Product introduction

Norflam Plus Tablet may be prescribed alone or in combination with another medicine. It should be taken with food. This will prevent you from getting an upset stomach. You should take it strictly as advised by your doctor. Do not take more or use it for a longer duration than recommended by your doctor.

This medicine may cause few common side effects such as nausea, indigestion, stomach pain, restlessness, and increased heart rate. If you experienced any such side effects that do not resolve with time or get worse, you should let your doctor know. Your doctor may help with ways to reduce or prevent them.

The medicine may not be suitable for everybody. Before taking it, let your doctor know if you have any medical conditions or disorders. Let your doctor also know all the other medicines you are taking. Pregnant and breastfeeding mothers should consult their doctors first before using the medicine.

Uses of Norflam Plus Tablet

Benefits of Norflam Plus Tablet

Pain relief
Norflam Plus Tablet is a combination of medicines used to treat aches and pains. It blocks chemical messengers in the brain that tell us we have pain. It is effective in relieving pain caused by headache, migraine, nerve pain, toothache, sore throat, period (menstrual) pains, arthritis and muscle aches.
Take it as it is prescribed to get the most benefit. Do not take more or for longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time.

Side effects of Norflam Plus Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Norflam Plus
  • Nausea
  • Indigestion
  • Stomach pain
  • Restlessness
  • Increased heart rate
  • Heartburn

How to use Norflam Plus Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Norflam Plus Tablet is to be taken with food.

How Norflam Plus Tablet works

Norflam Plus Tablet is a combination of two pain relievers (Ibuprofen, Paracetamol) and a stimulant (Caffeine). The pain relievers work by blocking the release of certain chemical messengers in the brain that cause pain and inflammation (redness and swelling). The presence of Caffeine increases the effectiveness of Paracetamol / Acetaminophen.

Quick tips

  • You have been prescribed this combination medicine to relieve pain, inflammation, and fever.
  • Take it with food to avoid getting an upset stomach.
  • It may cause dizziness and sleepiness. Don't drive or do anything that requires mental focus until you know how it affects you.
  • Avoid consuming alcohol when taking Norflam Plus Tablet as it may cause excessive drowsiness and increase the risk of liver damage.
  • Do not take it with any other medicine containing paracetamol (drugs for pain/fever or cough-and-cold) without asking your doctor first.
  • Take it as per the dose and duration prescribed by your doctor. Long term use may lead to stomach bleeding and kidney problems.

Safety advice

Alcohol

Alcohol

UNSAFE
It is unsafe to consume alcohol with Norflam Plus Tablet.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Norflam Plus Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding

Breast feeding

CAUTION
Norflam Plus Tablet should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.
Driving

Driving

UNSAFE
Norflam Plus Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

CAUTION
Norflam Plus Tablet should be used with caution in patients with kidney disease. Dose adjustment of Norflam Plus Tablet may be needed. Please consult your doctor.
Use of Norflam Plus Tablet is not recommended in patients with severe kidney disease. Long term use of this medicine can affect the kidney function.
Liver

Liver

CAUTION
Norflam Plus Tablet should be used with caution in patients with liver disease. Dose adjustment of Norflam Plus Tablet may be needed. Please consult your doctor.
However, the use of Norflam Plus Tablet is not recommended in patients with severe liver disease and active liver disease.

Frequently asked questions

Norflam Plus Tablet is a combination of three medicines: Ibuprofen, Paracetamol and caffeine. This medication helps to relieve pain and fever. It works by lowering the chemical substance in the body which causes pain, fever and inflammation. The presence of Caffeine increases the effectiveness of Paracetamol.
Norflam Plus Tablet is usually used for a short term and can be discontinued when symptoms are relieved. However, Norflam Plus Tablet should be continued if the doctor has advised to do so.
Yes, the use of Norflam Plus Tablet can cause nausea and vomiting. Taking it with milk, food or with antacids can prevent nausea. Avoid taking fatty or fried foods along with this medication. If you start to experience vomiting, drink plenty of water or other fluids by taking small frequent sips. Talk to your doctor if vomiting persists and you notice signs of dehydration, like dark colored and strong-smelling urine and a low frequency of urination. Do not take any other medicine without speaking to your doctor.
Yes, the use of Norflam Plus Tablet can cause dizziness (feeling faint, weak, unsteady or lightheaded) in some patients. If you feel dizzy or lightheaded, it is better to rest for some time and resume once you feel better.
The use of Norflam Plus Tablet is considered to be harmful for patients with known allergy to painkillers (NSAIDs) or any of the components or excipients of this medicine. The use of this medication should preferably be avoided in patients having a history of stomach ulcers or in patients who have active, recurrent stomach ulcer / bleeding. It should also be avoided in patients with a history of heart failure, high blood pressure or any underlying liver or kidney disease.
Yes, Norflam Plus Tablet can cause insomnia. Take Norflam Plus Tablet in the morning or afternoon to avoid insomnia. Consult the doctor if you are having persistent sleeping problem or insomnia (inability to sleep) while taking this medicine.
Yes, the long-term use of Norflam Plus Tablet can cause damage to the kidneys. Normal kidneys produce a chemical called prostaglandins that protects them from damage. Use of painkillers lower the levels of prostaglandins in the body which leads to kidney damage on long-term use. Use of painkillers is not recommended in patients with underlying kidney disease.
No, taking more of this medicine will not make it more effective, rather it can lead to increased side effects. If the symptoms are getting severe despite taking the medicine, please consult the doctor for re-evaluation.
Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Fact Box

Habit Forming

No

Therapeutic Class

PAIN ANALGESICS

References

  1. Derry CJ, Derry S, Moore RA. Single dose oral ibuprofen plus paracetamol (acetaminophen) for acute postoperative pain. Cochrane Database Syst Rev. 2013;(6):CD010210. [Accessed 22 Apr. 2019] (online) Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Brussels Laboratories Pvt Ltd
Address: 33 CHANGODAR INDUSTRIALESTATE SARKHEJ- BAVLA ROAD CHANGODAR DIST-AHMEDABAD GJ 382210 IN

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?
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Prescriptions are complex documents. We proof read and recheck at various steps to provide you the right medication in the correct form and dose
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In accordance with the law
Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945
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