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Composition for NISGIN


food interaction for NISGIN

alcohol interaction for NISGIN

pregnancy interaction for NISGIN

lactation interaction for NISGIN

There is no data available. Please consult doctor before consuming the drug.
Nisgin tablet may cause excessive drowsiness and calmness with alcohol.
Nisgin tablet is unsafe to use during pregnancy.
There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening situations. Please consult your doctor.
Unknown. Human and animal studies are not available. Please consult your doctor.




Nimesulide is used to treat acute pain, osteoarthritis (pain and swelling of joints due to degeneration) and pain during periods.

How it works

Nimesulide belongs to a class of medications called non-steroidal anti-inflammatory drugs (NSAIDs) which works by blocking the production of prostaglandins (a chemical associated with pain) thereby relieving pain and inflammation.

Common side effects

Nausea, Rash, Abnormal blood cell count, Anemia, Constipation, Diarrhoea, Dizziness, Shortness of breath, Gastritis, Hypersensitivity reaction, Increased blood pressure, Swelling, Increased sweating, Itching, Liver enzyme increased, Vomiting


Chlorzoxazone is used to relieve pain and stiffness caused by muscle strains and sprains. 

How it works

Chlorzoxazone is a centrally acting muscle relaxant that causes muscle relaxation and reduces muscle stiffness by blocking nerve impulses (or pain sensations) that are sent to the brain of the central nervous system.

Common side effects

Nervousness, Ovarian hyperstimulation syndrome, Body ache, Dark colored urine, Dizziness, Drowsiness, Liver toxicity, Lightheadedness, Nausea


No substitutes found

Expert advice for NISGIN

Do not take this medicine:
  • if you are allergic to Nimesulide, or any of the other ingredients of this medicine.
  • if you have or had gastric ulceration/bleeding in the past.
Do not consume more than one pain-relieving medication at a time.Caution is advised with the use of Nimesulide if you have bleeding disorder. Nimesulide may cause infertility in women, and should not be consumed by women planning to become pregnant This medicine should not be given to a child under 12 years of age.
Treatment with Nimesulide should be of short duration and discontinued if it is of no help.

Frequently asked questions for NISGIN


Q. Is Nimesulide an antibiotic?
No, Nimesulide is non-steroidal anti-inflammatory drug (NSAIDs; pain-relieving drug) which relieves acute pain in conditions like joint pain and period pain. However, it may be used with antibiotics to relieve pain associated with certain infections.
Q. Can I take Nimesulide with paracetamol or ibuprofen?
Nimesulide, paracetamol and ibuprofen are non-steroidal anti-inflammatory drugs (NSAIDs; pain-relieving drugs). Taking two NSAID drugs together is not advisable as it may increase the potential for gastric ulceration and bleeding.
Q. Does Nimesulide contain aspirin or sulphur?
No. Nimesulide is a non-steroidal anti-inflammatory drug (NSAIDs; pain-relieving drug) doesn’t contain aspirin or sulphur.
Q. Is Nimesulide safe?
Nimesulide is safe at prescribed dose and duration as advised by your doctor.


Q. Is chlorzoxazone an opiate/ narcotic/ steroid/ controlled substance/ addictive?
No. Chlorzoxazone is mephenesin like centrally acting muscle relaxant that is used to relieve muscle stiffness and pain. It is not a steroid, narcotic, addictive or controlled substance.
Q. Does chlorzoxazone be used for recreational purposes?
No, chlorzoxazone or any other drug should not be used for recreational purpose. Use only when prescribed by the doctor.
Q. Does chlorzoxazone have aspirin or codeine in it?
No. It does not contain aspirin or codeine.
Q. Does chlorzoxazone induce drowsiness/ weight gain?
It is not known to cause weight gain, but may cause drowsiness. If you experience any such side effects, consult your doctor.
Q. Is chlorzoxazone like Vicodin?
No. Vicodin, which contains acetaminophen and hydrocodone, is used to relieve general pain. Chlorzoxazone is a muscle relaxant and different drug altogether.
Q. Is chlorzoxazone the same as Soma?
No. Soma caontains carisoprodol, another mephenesin-like centrally acting muscle relaxant. However, it totally different from chlorzoxazone.
Q. Can I take chlorzoxazone with tramadol, naproxen or ibuprofen?
No known interaction data is available for these drugs. However, it doesn’t mean that the chlorzoxazone can be taken with tramadol, naproxen or ibuprofen. Always consult your doctor regarding the drug usage.
Q. Can I take chlorzoxazone with hydrocodone/ citalopram/ acetaminophen?
No. It is advisable not to take chlorzoxazone with hydrocodone/ citalopram/ acetaminophen since interactions have been reported for this combination.


Content on this page was last updated on 10 October, 2015, by Dr. Varun Gupta (MD Pharmacology)