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Nirhes Injection is used for short-term fluid replacement after trauma. It is used in the treatment of hypovolemia that can result due to any injury, surgery, or severely ill patients.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 22 Sep 2025 | 02:14 AM (IST)
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General Information

Contains

Hydroxyethyl Starch(HES) (6% w/v)

Marketer

Aculife Healthcare Private Limited
The content is shown in English
Nirhes Injection image
Nirhes Injection image

Product introduction

Nirhes Injection is a large weight molecular substance that remains restricted to the blood vessels and works by producing pressure in the blood which is known as oncotic pressure. This injection must be administered under the supervision of a healthcare professional.

You should not get this injection if you have any known allergies to this medicine. Before taking it, inform the doctor you are suffering from any severe heart disease. Your doctor may check your blood pressure and ask you to get regular blood tests done while you are using this injection.

The most common side effects include injection site reactions (pain, swelling, redness). To make sure it is safe for you, let your doctor know if you are pregnant or breastfeeding. Let your doctor also know if you have any kidney or liver diseases as a dose adjustment may be required.

Uses of Nirhes Injection

  • Short term fluid replacement after trauma

Benefits of Nirhes Injection

Short term fluid replacement after trauma
Trauma or major surgery can cause sudden blood or fluid loss, leading to low blood volume and blood pressure. Nirhes Injection is used as a plasma volume expander to quickly restore lost fluids in such cases. It helps stabilize circulation and maintain adequate blood flow to vital organs.

Side effects of Nirhes Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Nirhes
  • Injection site reactions (pain, swelling, redness)

How to use Nirhes Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Nirhes Injection works

Nirhes Injection is a large molecular weight substance that remains restricted to the blood vessels and generates oncotic pressure (pressure produced by proteins in the blood).

Quick tips

  • Nirhes Injection is used to replace fluid loss from the body after any surgery or trauma.
  • Nirhes Injection should be used with caution in patients with diabetes, hypokalemia (low potassium), kidney disease and edema.
     
  • Your blood pressure and heart rate will be monitored regularly while taking Nirhes Injection.
  • Your blood sugar level will be monitored regularly while taking Nirhes Injection.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Nirhes Injection. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Nirhes Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Information regarding the use of Nirhes Injection during breastfeeding is not available. Please consult your doctor.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Nirhes Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney

Kidney

CAUTION
Nirhes Injection should be used with caution in patients with kidney disease. Dose adjustment of Nirhes Injection may be needed. Please consult your doctor.
Liver

Liver

CAUTION
Nirhes Injection should be used with caution in patients with liver disease. Dose adjustment of Nirhes Injection may be needed. Please consult your doctor.

Fact Box

Chemical Class

Nonionic Starch Derivative

Habit Forming

No

Therapeutic Class

BLOOD RELATED

Action Class

Colloids (Plasma Substitutes)

References

  1. ScienceDirecct. Hydroxyethyl Starch. [Accessed 07 Apr. 2019] (online) Available from:
  2. Central Drugs Standard Control Organisation (CDSCO). [Accessed 07 Apr. 2019] (online) Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Aculife Healthcare Private Limited
Address: Commerce House-V, Besides Vodafone House, Prahlad Nagar Corporate Road, Ahmedabad, Gujarat 380051

Vendor Details

Country of origin: India

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