Nexluma Capsule

Lumateperone (42mg)

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Nexluma Capsule is an atypical antipsychotic used to treat depressive episodes associated with bipolar I and bipolar II disorder in adults. It may be used alone or in combination.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 06 Aug 2026 | 01:07 AM (IST)

₹295 MRP ₹328.1310% off

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Lumavibe 42mg Capsule

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Nexluma Capsule

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Lumateperone (42mg)

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General Information

Contains

Lumateperone (42mg)

Marketer

Sun Pharma Laboratories Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Take Nexluma Capsule exactly as prescribed by your doctor. It can be taken with or without food. Continue taking the medicine regularly, even if you start feeling better, unless your doctor advises you to stop. Do not change the dose or stop treatment without consulting your doctor.

Limited data available on the common side effects of Nexluma Capsule. However, some individuals may experience nausea, sleepiness (somnolence), dry mouth, and dizziness. Inform your doctor if they persist or become troublesome.

Do not take Nexluma Capsule if you are allergic to it or any of its ingredients. Tell your doctor about all medicines you are taking before starting treatment, especially medicines that strongly affect the liver enzymes or medicines that cause drowsiness, as they may interact with Nexluma Capsule. Use this medicine during pregnancy or breastfeeding only if your doctor determines that the benefits outweigh the risks. Until you know how the medicine affects you, avoid driving or operating machinery if you feel sleepy or dizzy.

Uses of Nexluma Capsule

Bipolar depression

Benefits of Nexluma Capsule

Bipolar depression
Nexluma Capsule helps treat depressive episodes associated with bipolar I and bipolar II disorder in adults. It can be used alone or together with other medicines used in bipolar depression to help improve symptoms of bipolar depression. It may improve mood, interest in daily activities, energy levels, and overall functioning. Regular treatment as prescribed can help individuals better manage episodes of bipolar depression.

Side effects of Nexluma Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Nexluma

Limited data available

How to use Nexluma Capsule

Take this medicine in the dose and duration as advised by your doctor. Nexluma Capsule may be taken with or without food.

How Nexluma Capsule works

Nexluma Capsule is an atypical antipsychotic. It works by helping restore the balance of certain natural chemicals in the brain that influence mood and behavior. It acts on serotonin and dopamine pathways, reduces the reuptake of serotonin, and also helps regulate glutamate activity. Together, these actions help improve symptoms of bipolar depression.

All substitutes for Nexluma Capsule

For information purposes only. Consult a doctor before taking any medicine.

Lumazyl Capsule

by Intas Pharmaceuticals Ltd

₹34.2/capsule

16% costlier

Lumavibe 42mg Capsule

by Torrent Pharmaceuticals Ltd

₹32.4/capsule

10% costlier

Quick tips

Take Nexluma Capsule exactly as prescribed and do not stop treatment without consulting your doctor, even if you begin to feel better.
Be cautious while taking alcohol during treatment, as it can increase drowsiness and dizziness caused by the medicine.
Tell your doctor about all prescription medicines, over-the-counter medicines, and herbal supplements you are taking.
If you feel sleepy or dizzy after taking Nexluma Capsule avoid driving or operating heavy machinery until you know how the medicine affects you.
Tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding before starting treatment so the benefits and risks can be assessed.

Safety advice

Alcohol

CAUTION

Alcohol should be used with caution while taking Nexluma Capsule.

Pregnancy

CONSULT YOUR DOCTOR

The safety of Nexluma Capsule during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

CONSULT YOUR DOCTOR

Nexluma Capsule may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

UNSAFE

Nexluma Capsule may cause side effects that could affect your ability to drive.

Kidney

CONSULT YOUR DOCTOR

There is limited data available on the use of Nexluma Capsule in patients with kidney disease. Please consult your doctor.

Liver

CONSULT YOUR DOCTOR

There is limited data available on the use of Nexluma Capsule in patients with liver disease.

Frequently asked questions

Can Nexluma Capsule be used alone, or do I need to take it with other medicines?

It can be used either on its own (monotherapy) or together with lithium or valproate (adjunctive therapy) to treat depressive episodes associated with bipolar I or bipolar II disorder. Your doctor will decide whether Nexluma Capsule alone is suitable for you or if combining it with another medicine is more appropriate based on your medical condition and treatment response.

What is the difference between bipolar I disorder and bipolar II disorder?

Both bipolar I and bipolar II are types of bipolar disorder that involve episodes of depression, but they differ in the type of mood elevation experienced. People with bipolar I disorder have had at least one manic episode, where they feel extremely energetic, unusually excited, or overly active, often affecting daily life and sometimes requiring medical care. People with bipolar II disorder experience hypomanic episodes, which are milder than mania and usually do not cause severe impairment or require hospitalization. Both conditions can cause depressive episodes, and your doctor will determine the most appropriate treatment based on your diagnosis.

Are there any medicines that may interact with this medicine?

Yes. Some medicines can affect the way Nexluma Capsule works. In particular, medicines that strongly affect the CYP3A4 enzyme may increase or decrease the amount of this medicine in your body. Medicines that cause drowsiness, such as certain sleeping pills, anxiety medicines, or opioid pain medicines, may also increase sleepiness when taken together. Always tell your doctor about all the medicines and supplements you are taking before starting treatment.

What should I do if I accidentally take more Nexluma Capsule than prescribed?

If you think you have taken more Nexluma Capsule than prescribed, seek medical attention immediately. Treatment mainly involves close medical monitoring and supportive care while doctors manage the symptoms and assess whether other medicines may also be involved.

Why should I be careful while driving after taking Nexluma Capsule?

Some people may experience sleepiness (somnolence) or dizziness while taking Nexluma Capsule, especially during the initial stages of treatment. Until you know how the medicine affects you, avoid driving, operating heavy machinery, or performing activities that require full attention. If these symptoms continue or become bothersome, speak with your doctor.

Should I inform my doctor before starting any new medicine?

Yes. Always inform your doctor before starting any new prescription medicine, over-the-counter medicine, or herbal supplement while taking Nexluma Capsule. Some medicines can interact with it and may affect how well it works or increase the risk of side effects.

Fact Box

Chemical Class

Alkyl-phenylketones

Habit Forming

Therapeutic Class

NEURO CNS

Action Class

Atypical Antipsychotics

References

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Sun Pharma Laboratories Ltd
Address: Vill: Kokjhar, Mirza Palashbari Road, P. O.: Palashbari, Dist: Kamrup. Assam-781128.

Vendor Details

Country of origin: India

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Home

Neuro Cns

Atypical Antipsychotics

Nexluma Capsule

Nexluma Capsule

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Nexluma Capsule

Benefits of Nexluma Capsule

Side effects of Nexluma Capsule

How to use Nexluma Capsule

How Nexluma Capsule works

All substitutes for Nexluma Capsule

Lumazyl Capsule

Lumavibe 42mg Capsule

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

Can Nexluma Capsule be used alone, or do I need to take it with other medicines?

What is the difference between bipolar I disorder and bipolar II disorder?

Are there any medicines that may interact with this medicine?

What should I do if I accidentally take more Nexluma Capsule than prescribed?

Why should I be careful while driving after taking Nexluma Capsule?

Should I inform my doctor before starting any new medicine?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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