Overview
Uses and benefits
Side effects
How to use
How drug works
Safety advice
Missed dose
All substitutes
Quick tips
Fact box
Patient concerns
FAQs

Author Details

Written By

Dr. Anuj Saini

MMST, MBBS

Reviewed By

Dr. Sachin Gupta

MD Pharmacology, MBBS

Last updated

12 Nov 2025 | 06:22 PM (IST)

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Neurolib Trio Gel

Prescription Required

Marketer

Libramed Pharmaceuticals Private Ltd

SALT COMPOSITION

Gabapentin (6% w/w) + Lidocaine (5% w/w) + Baclofen (2% w/w)

Storage

Store below 25°C

Preservative

Methylparaben, Propyl paraben

View available alternative with same salt composition

Click here to view all substitutes

Product introduction

Neurolib Trio Gel is a prescription medicine used for the treatment of neuropathic pain. It works by first cooling and then warming up the skin. Thus, it calms the damaged or overactive nerves by acting on the brain, thereby decreasing the sensation of pain.

Neurolib Trio Gel is for external use only. You should use this in the dose and duration advised by your doctor. Clean and dry the affected area before applying this medicine to the skin. You should always wash your hands after applying it unless hands are the affected area.

There are no major side effects associated with this medicine, but it can cause some application site burning, irritation, itching or redness. However, these side effects are temporary and usually resolve on their own. Please consult your doctor if these do not subside or bother you.

Uses of Neurolib Trio Gel

Neuropathic pain

Benefits of Neurolib Trio Gel

In Neuropathic pain

Neurolib Trio Gel is used to treat long-lasting (chronic) pain caused by nerve damage due to diabetes, shingles or spinal cord injury. It interferes with pain signals that travel through the damaged nerves and the brain. Using this medicine regularly will improve your physical and social functioning and overall quality of life.

Side effects of Neurolib Trio Gel

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Neurolib Trio

Application site reactions (burning, irritation, itching and redness)

How to use Neurolib Trio Gel

This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the gel. Wash your hands after applying, unless hands are the affected area.

How Neurolib Trio Gel works

Neurolib Trio Gel is composed of three medicines gabapentin, lidocaine and baclofen. Gabapentin works by binding to calcium channels in nerve cells, which reduces the release of pain signals and calms overactive nerves involved in neuropathic pain. Lidocaine is a local anesthetic that blocks sodium channels on nerve endings, preventing the transmission of pain signals from the affected area to the brain. Baclofen acts on GABA receptors in the spinal cord to reduce nerve excitability and relieve muscle spasms that may accompany nerve pain. Together, these three components target different mechanisms of pain, offering effective relief from the burning, tingling, and shooting sensations commonly seen in neuropathic conditions.

Safety advice

Alcohol

No interaction found/established

Pregnancy

CONSULT YOUR DOCTOR

The safety of Neurolib Trio Gel during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

SAFE IF PRESCRIBED

Neurolib Trio Gel may be safe to use during breastfeeding. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Driving

No interaction found/established

Kidney

No interaction found/established

Liver

No interaction found/established

What if you forget to take Neurolib Trio Gel?

If you miss a dose of Neurolib Trio Gel, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Neurolib Trio Gel

₹187/Gel

Gabipenta Gel

Leeford Healthcare Ltd

₹140/gel

32% cheaper

GABAgesic Gel

Linux Laboratories

₹411.5/gel

100% costlier

Gabanyl Gel

Leeford Healthcare Ltd

₹164/gel

20% cheaper

Gabalov Gel

Lovis Laboratories Private Limited

₹243.7/gel

19% costlier

Arigaba Gel

Pure and Cure Healthcare Private Limited

₹246.5/gel

20% costlier

Quick tips

Neurolib Trio Gel is used to treat certain types of long-lasting pain caused by damage to nerves.
Avoid contact with the eyes, mouth, nose and rinse thoroughly in case of accidental contact or seek medical help in case of swallowing.
Inform your doctor if you are taking any other pain-relieving medicines.
Along with taking Neurolib Trio Gel, your doctor might advise you to undergo physiotherapy to get relief from pain.

Fact Box

Habit Forming

Therapeutic Class

NEURO CNS

Patient concerns

Most of the times when I get excited or have orgasm I feel pain in my testis and around it .

Dr. Pranay Gandhi

Sexology

hi PATIENT neuropathic pain mostly. take tablet emanzen d 1 bd

Sir Plz suggest me effective pain killer with minimum side effects for back pain and arthritis, which can be taken on regular basis as and when required.

Dr. Vikas Sharma

Neurology

dpeneds on the type of pain - muscular or neuropathic; show tro nearby neuro

I m suffering due to pain in left testis, so I visited pgimer Chandigarh in urology deptt. There I had gone for dopler ultrasound testis and its reports are normal Now whenever I lay down at bed I felt a smaal lump in testis,when I touchdown it, the pain radiates in whole left testis Now I m feeling pain sometimes in both tastis Is it a sign of early vericoseal Or something else Pls. Suggest

Dr. Pranay Gandhi

Sexology

it is a neuropathic pain and it won't show any abnormality in USG. i am worried about the lump u r talking about. its better if u consult a surgeon, PGIMER UROLOGY is the best place to go for examination. if they say its normal, its normal. for pain take pregaba m 1 od

What is Neurolib Trio Gel used for?

Neurolib Trio Gel is used to treat neuropathic pain caused by nerve damage. A doctor may also prescribe this medicine to manage pain associated with joints or injury.

Can I use Neurolib Trio Gel for aching joints or sore muscles?

Yes, Neurolib Trio Gel can be used for local joint and muscle pain due to nerve problems, muscle tightness, or chronic pain conditions such as back pain, arthritis, etc.

What if I feel burning, redness, or irritation after using Neurolib Trio Gel?

Mild irritation may occur after applying Neurolib Trio Gel. However, if it persists or gets worse, stop using the medicine and contact your doctor.

Can Neurolib Trio Gel be used for diabetic nerve pain or post-surgical pain?

Yes, Neurolib Trio Gel is often prescribed for diabetic neuropathy and nerve pain after some surgeries to provide local relief.

What should I do if my pain does not improve or my skin worsens after using Neurolib Trio Gel?

If you see no benefit, or your pain or skin symptoms get worse, stop using Neurolib Trio Gel and see your doctor for further advice.

Can I use other creams, sunscreens, or cosmetics with Neurolib Trio Gel?

You should leave a 30-minute gap before or after using other skin products and Neurolib Trio Gel to avoid reactions or reduce effectiveness.

Should I cover the treated area with a bandage after applying Neurolib Trio Gel?

Do not use dressings or bandages after applying Neurolib Trio Gel unless your doctor specifically tells you. This may increase absorption and potential side effects.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Stahl SM, editor. Gabapentin. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 275-77.
McNamara JO. Pharmacotherapy of the Epilepsies. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 599.
Porters RJ, Meldrum BS. Antiseizure Drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 410.
White PF, Katzung BG. Skeletal Muscle Relaxants. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 463.
White PF, Katzung BG. Skeletal Muscle Relaxants. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 451-468.