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Nefodol Tablet is a combination of two pain-relieving medicines. It is used to relieve pain in various conditions. It works by blocking the transmission of pain signals to the brain, thereby decreasing pain perception.

Written By Dr. Syeda Aafia, MBA, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 15 Jan 2026 | 09:39 AM (IST)
₹125 MRP ₹135.948% off 
As per Ministry of Health and Family Welfare
 
 
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Nefodol Tablet image
Nefodol Tablet image
Nefodol Tablet image
Nefodol Tablet image

Product introduction

Nefodol Tablet may be taken with or without food. Take it in the exact dose and duration prescribed by your doctor. Do not take this medicine more than the recommended dose; high doses may have harmful effects on the body. Prolonged use of this medicine may harm your health. Do not take it for more than the prescribed duration unless your doctor advises you to do so.


Common side effects of Nefodol Tablet include drowsiness, nausea, vomiting, sweating, lightheadedness, and abdominal pain. If any of these side effects persist or worsen, discuss them with your doctor. They may be able to adjust your dosage.


Before using this medicine, let your doctor know if you have any medical conditions such as liver or kidney disease. Immediately consult your doctor if you experience any allergic reactions such as skin rashes, swelling, and itching. Let your doctor also know about all the medications you are taking, as some medicines may interact with Nefodol Tablet.

Uses of Nefodol Tablet

Benefits of Nefodol Tablet

Pain relief
Nefodol Tablet is used to relieve pain, inflammation, and swelling in conditions such as osteoarthritis, rheumatoid arthritis, muscle pain, gout, and fever. Also, it effectively relieves muscle stiffness or spasm, thereby improving muscle movement. Taking it will help you go about your daily life more easily. If the injury is severe or lasts a long time, you may also need to take painkillers or you can even consider physiotherapy. Consult a doctor if you are not sure.

Side effects of Nefodol Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Nefodol
  • Nausea
  • Dizziness
  • Drowsiness
  • Vomiting
  • Sweating
  • Lightheadedness
  • Tremors
  • Hypotension (low blood pressure)
  • Abdominal pain
  • Diarrhea
  • Urinary retention
  • Allergic reaction

How to use Nefodol Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Nefodol Tablet may be taken with or without food.

How Nefodol Tablet works

Nefodol Tablet is a combination of two medicines: nefopam and paracetamol. Nefopam is a non-opioid pain reliever. It works by blocking the transmission of pain signals to the brain, thereby decreasing pain perception. Paracetamol is an analgesic (pain reliever) and antipyretic (fever reducer). It works by blocking the release of certain chemical messengers that cause pain and fever.

Quick tips

  • Consider taking Nefodol Tablet with a glass of milk to prevent an upset stomach.
  • Stick to simple meals and avoid spicy food to avoid feeling sick (nausea).
  • Inform your doctor if you are planning to have an operation (even a minor one, such as tooth extraction) since Nefodol Tablet might increase the risk of bleeding.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Nefodol Tablet. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Information regarding the use of Nefodol Tablet during pregnancy is not available. Please consult your doctor.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Information regarding the use of Nefodol Tablet during breastfeeding is not available. Please consult your doctor.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Nefodol Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Kidney

Kidney

CONSULT YOUR DOCTOR
There is limited data available on the use of Nefodol Tablet in patients with kidney disease. Please consult your doctor.
Liver

Liver

CONSULT YOUR DOCTOR
There is limited data available on the use of Nefodol Tablet in patients with liver disease.

Frequently asked questions

The exact time Nefodol Tablet takes to relieve pain is not known. However, you may start noticing pain relief within an hour.
If you have chronic pain persisting for a long time without any improvement, consult your doctor to rule out the cause and tailor a treatment plan. Do not take Nefodol Tablet on your own.
No, taking other painkillers along with Nefodol Tablet without consulting a doctor may cause serious harm to the body. Inform your doctor beforehand if you are taking any medicine, including supplements and herbals, before starting Nefodol Tablet.
You should stop taking Nefodol Tablet if you experience any allergic reaction, such as shortness of breath, skin rashes, swelling of the face or lips, etc. Reach out to your prescribing doctor at the earliest.
Yes, Nefodol Tablet can make you sleepy and dizzy. You should avoid indulging in skilful tasks such as driving or operating machines until the symptoms reduce.
Individuals should avoid taking Nefodol Tablet if they are allergic to any ingredient present in Nefodol Tablet, have liver damage, anemia, a heart ailment, or a lung ailment. Inform your doctor before starting Nefodol Tablet treatment.

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User feedback

Pain relief
100%
Average
67%
Excellent
33%
Gastric irritation
50%
Nausea
50%
With food
100%
Average
50%
Expensive
50%
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Medley Pharmaceuticals
Address: Plot No. D2 Medley House,Street No. 6 M.I.D.C. Area, Andheri (East), Mumbai-400 093, INDIA

Vendor Details

Country of origin: India
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