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Migrafen Tablet is a prescription medicine used to treat migraine. It helps by narrowing the blood vessels, thereby relieving migraine headaches.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 02 Mar 2026 | 11:04 AM (IST)
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The content is shown in English
Migrafen Tablet image
Migrafen Tablet image
Migrafen Tablet image
Migrafen Tablet image
Migrafen Tablet image

Product introduction

Migrafen Tablet is taken by mouth with or without food, preferably at night. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Do not skip any doses and finish the full course of treatment even if you feel better. In case you miss a dose of this medicine, take it as soon as you remember. You should continue to take this medicine for as long as advised by the doctor. Do not stop taking it suddenly as this may worsen your headaches.

Some common side effects of this medicine include nausea, vomiting, diarrhea, muscle pain, and increased heart rate. It may also cause dizziness, so do not drive or operate machinery, until you know how this medicine affects you. It might cause dryness of mouth if it happens then drink plenty of water and avoid foods that are acidic (like lemons), spicy and salty.

Take caution while taking medicine if you are suffering from liver or kidney disease. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Uses of Migrafen Tablet

Benefits of Migrafen Tablet

Migraine
Migrafen Tablet is a combination of medicines that treat and prevent migraine headaches. It changes the electrical activity in the brain, and also blocks signals that cause nausea/vomiting associated with migraines. It also contains caffeine that stimulates your brain to uplift your mood and give you a feeling of well being by improving your energy levels. By preventing and reducing the frequency of migraine headaches, it can help you carry out your daily activities and have a better quality of life.

Side effects of Migrafen Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Migrafen
  • Nausea
  • Vomiting
  • Diarrhea
  • Muscle pain
  • Increased heart rate
  • Restlessness

How to use Migrafen Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Migrafen Tablet may be taken with or without food.

How Migrafen Tablet works

Migrafen Tablet is a combination of two medicines: Ergotamine and Caffeine, which treats migraine. Ergotamine is an ergot alkaloid which works by preventing blood vessels in the head from expanding and causing headaches. Caffeine increases the absorption of Ergotamine and further narrows the widened blood vessels.

Quick tips

  • Migrafen Tablet helps to ease the pain you feel during a migraine headache.
  • Stick to simple meals and avoid fatty or spicy foods to avoid nausea and vomiting due to migraines.
  • Inform your doctor if you are taking any pain relief medicine.
  • Migrafen Tablet can only decrease the number and severity of attacks but may not completely stop them.
  • Some tips that may help avoid a migraine attack:
    1. Have your meals at the same time every day.
    2. Avoid bright lights and extreme temperatures.
    3. Avoid loud music and noisy places.
    4. Avoid chocolates,  cheese, processed food, alcohol, and smoking.
    5. Get sufficient sleep and avoid stress.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Migrafen Tablet. Please consult your doctor.
Pregnancy

Pregnancy

UNSAFE
Migrafen Tablet is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.
Breast feeding

Breast feeding

UNSAFE
Migrafen Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving

Driving

UNSAFE
Migrafen Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

CAUTION
Migrafen Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Liver

Liver

UNSAFE
Migrafen Tablet is unsafe to use in patients with liver disease and should be avoided.

Frequently asked questions

Certain physical or environmental factors, such as foods, hormonal changes, weather, and stress, can lead to or “trigger” a migraine. However, it is important to remember that triggers are different for everyone. Thus, to prevent migraine attacks you need to figure out which triggers affect you and which ones do not. Keeping a headache diary is an effective way to track triggers. The diary will also help you talk to your doctor about your condition better.
Keep this medicine in the packet or the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
Migrafen Tablet is usually used to prevent and treat migraine attack. Migrafen Tablet should be continued as advised by the doctor.
Yes, the use of Migrafen Tablet can cause dry mouth. If you experience dry mouth, drink plenty of water. Take regular sips during the day and keep some water by your bed at night. You may use lip balm if your lips are also dry. Try to avoid foods that are acidic (like lemons), spicy and salty.

Fact Box

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Leeford Healthcare Ltd
Address: Plot No. 5, Apparel Park-cum-Industrial Area, Village Katha, Baddi, Distt. Solan (HP) – 173205, India.

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Migrafen Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
Why we need a prescription?
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Provide right medicines
Prescriptions are complex documents. We proof read and recheck at various steps to provide you the right medication in the correct form and dose
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In accordance with the law
Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945
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