Metosafe 50mg Tablet

Reviewed By Dr. Mekhala Chandra, MD, MBBS

Last updated on 14 Jan 2026 | 03:53 PM (IST)

Metosafe 50mg Tablet belongs to a group of medicines called beta-blockers. It is used to treat high blood pressure (hypertension), angina (heart-related chest pain), and irregular heart rhythms (arrhythmia). It also helps prevent future heart attacks, strokes, and migraines.

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General Information

Contains

Metoprolol Tartrate (50mg)

Marketer

Zinnia Life Sciences

Storage

Store below 30°C

The content is shown in English

Product introduction

Metosafe 50mg Tablet is also used to relieve the symptoms caused by an overactive thyroid gland. It may be prescribed alone or together with other medications. The dose and frequency depend on what you are taking it for and the severity of your condition. It may be taken on an empty stomach or with a meal, but take it regularly at the same time each day to get the most benefit. It may take several weeks before you get the full benefit of this medicine, and you may need to take it for the rest of your life. However, it is important to continue taking it even if you feel well. Most people with high blood pressure do not feel ill, and if you stop taking it, your condition may worsen.

Common side effects of Metosafe 50mg Tablet include low blood pressure (hypotension), slow heart rate, headache, dizziness, and nausea. These are usually mild and short-lived. It may also cause shortness of breath or rash in some people. To reduce the risk of side effects, your doctor may start the medicine at a low dose and gradually increase it. Consult your doctor if the side effects bother you or do not go away.

Before taking it, let your doctor know if you have any liver problems. It may also not be suitable for people who have a slow heart rate, severe circulation problems, severe heart failure, or low blood pressure. Pregnant or breastfeeding mothers should also consult their doctor before taking it. You must talk to your doctor to find out whether this medicine is suitable for you to use. You should have your blood pressure checked regularly to make sure that this medicine is working properly. Avoid drinking alcohol, as it may increase certain side effects.

Uses of Metosafe Tablet

Benefits of Metosafe Tablet

Treatment of Angina (heart-related chest pain)
Metosafe 50mg Tablet relaxes the blood vessels so that blood can flow more easily around your body and makes sure that your heart is getting a good supply of oxygen. This makes it less likely that you will suffer chest pain caused by angina. This medicine can help increase your ability to exercise and go about your daily life more easily by reducing the frequency of angina attacks. You should take it regularly and as long as it is prescribed for it to work effectively.

Treatment of Arrhythmia
Metosafe 50mg Tablet is used to stabilize heart rhythms (particularly atrial fibrillation). It helps in normalizing an abnormal heart rhythm, preventing it from occurring in the first place, or slowing down the heart rate during an episode.

Prevention of Heart attack
Metosafe 50mg Tablet helps lower your blood pressure and make it easier for your heart to pump blood around your body. This reduces the chances of you having a heart attack. It can also reduce the risk of dying if it is given immediately after a heart attack. This medicine needs to be taken regularly to be effective, so keep taking it even if you feel well. Do not stop without talking to your doctor.

Treatment of Hypertension (high blood pressure)
Metosafe 50mg Tablet belongs to a group of medicine called long-acting beta-blocker. It works by blocking the effects of some chemicals on your heart and blood vessels. It slows down your heart rate and helps the heartbeat with less force. This lowers your blood pressure and helps in reducing your risk of having a stroke, a heart attack, other heart problems, or kidney problems in the future. This medicine needs to be taken regularly to be effective, so keep taking it even if you feel well. Do not stop without talking to your doctor.

Prevention of Migraine
Metosafe 50mg Tablet helps change electrical activity in the brain, reduce the flow of blood in your brain, or increase activity in a region of the brain associated with migraines. By preventing and reducing the frequency of migraine attacks, the medicine can help you carry out your daily activities and improve your quality of life.

Side effects of Metosafe Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Metosafe

Hypotension (low blood pressure)
Slow heart rate
Dizziness
Tiredness
Breathlessness
Diarrhea
Depression
Itching
Rash

How to use Metosafe Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Metosafe 50mg Tablet may be taken with or without food.

How Metosafe Tablet works

Metosafe 50mg Tablet is a short-acting beta blocker that works specifically on the heart. It works by slowing down the heart rate and making the heart more efficient at pumping blood around the body.

All substitutes for Metosafe 50mg Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Metosafe 50mg Tablet may cause dizziness. If this happens to you, get up slowly when rising from a sitting or lying position.
It can hide symptoms of low blood sugar if you are diabetic. Monitor your blood sugar levels regularly.
Do not stop taking Metosafe 50mg Tablet suddenly, as it can cause your blood pressure to rise suddenly, thereby increasing the risk of heart attack and stroke.
Monitor blood pressure and heart rate regularly to ensure the medication is working effectively.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Metosafe 50mg Tablet

Pregnancy

CONSULT YOUR DOCTOR

The safety of Metosafe 50mg Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

CONSULT YOUR DOCTOR

Metosafe 50mg Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

CONSULT YOUR DOCTOR

It is not known whether Metosafe 50mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.

Kidney

SAFE IF PRESCRIBED

Metosafe 50mg Tablet is safe to use in patients with kidney disease. No dose adjustment is recommended.

Liver

CAUTION

Metosafe 50mg Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.

Frequently asked questions

What is the difference between metoprolol succinate and Metosafe 50mg Tablet?

Metoprolol succinate is an extended-release form of metoprolol. This means it is released into your body slowly and only needs to be taken once a day. Metosafe 50mg Tablet, on the other hand, is available as an immediate-release tablet. It doesn’t stay in your body as long as metoprolol succinate does. Hence, multiple doses in a day may be required.

Is Metosafe 50mg Tablet effective?

Metosafe 50mg Tablet is effective if used in the dose and duration advised by your doctor. Do not stop taking it even if you see improvement in your condition. If you stop using Metosafe 50mg Tablet too early, the symptoms may return or worsen.

Which is better, Metosafe 50mg Tablet or metoprolol succinate?

Metosafe 50mg Tablet and Metoprolol succinate are both effective, depending on the condition being treated. Metoprolol succinate is more effective for treating heart failure. Metoprolol succinate may also be less likely to cause some side effects as compared to Metosafe 50mg Tablet.

Can I take alcohol while on treatment with Metosafe 50mg Tablet?

No, you should not take alcohol while on treatment with Metosafe 50mg Tablet. Drinking alcohol while taking Metosafe 50mg Tablet may increase the risk of drowsiness and dizziness. Therefore, it is generally not recommended to use Metosafe 50mg Tablet with alcohol. However, you may consult your doctor if you have any concerns regarding the same.

Can you switch from Metosafe 50mg Tablet to Metoprolol Succinate?

Yes, in some cases, Metosafe 50mg Tablet may be switched to metoprolol succinate. Metoprolol succinate may be preferred for its once-daily dosing. Consult a doctor to determine your treatment options when switching medications to know what suits you best and to get maximum benefit.

When should you not take Metosafe 50mg Tablet?

Metosafe 50mg Tablet should not be taken if you experience very low heart rates, low blood pressure, or severe heart failure. It is important to discuss your medical history with a doctor to determine if you should be on Metosafe 50mg Tablet or not.

What should I avoid while taking Metosafe 50mg Tablet?

Alcohol and certain medications should be avoided while taking Metosafe 50mg Tablet. Some medications, including calcium channel blockers, certain antidepressants, and those processed in a similar way as Metosafe 50mg Tablet, may increase the risk of adverse effects with Metosafe 50mg Tablet.

Can I use Metosafe 50mg Tablet in pregnancy?

No, Metosafe 50mg Tablet should not be used in pregnancy. It may be used during pregnancy if the benefits outweigh the risks. Not enough studies have been done to show that this medication is safe during pregnancy. Consult a doctor if you are planning a baby, pregnant, or breastfeeding, to avoid any harmful effects on the baby.

Can Metosafe 50mg Tablet cause low blood potassium levels (hypokalemia)?

As per a recent alert issued by the government, Metosafe 50mg Tablet may cause low blood potassium levels (hypokalemia), but the intensity of this effect has not been established so far.

Fact Box

Chemical Class

Tyrosol derivative

Habit Forming

Therapeutic Class

CARDIAC

Action Class

Beta blocker- Cardioselective

Related lab tests

Kidney Function Test

References

Benowitz NL. Antihypertensive Agents. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 182.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 904-905.
Metoprolol tartrate [Prescribing Information]. East Hanover, New Jersey: Novartis Pharmaceuticals Corporation; 2008. [Accessed 20 Feb. 2025] (online) Available from:
Metoprolol tartrate [Prescribing Information]. Sun Pharmaceutical Industries Limited; 2024. [Accessed 04 Feb. 2025] (online) Available from:

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Zinnia Life Sciences
Address: No : 122 VINAYAKA LAYOUT, MARANAHALLI, VIJAYA NAGAR, BANGALORE 560 040.

Vendor Details

Country of origin: India

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Why we need a prescription?

Provide right medicines

Prescriptions are complex documents. We proof read and recheck at various steps to provide you the right medication in the correct form and dose

In accordance with the law

Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945

Metosafe 50mg Tablet

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Metosafe Tablet

Benefits of Metosafe Tablet

Side effects of Metosafe Tablet

How to use Metosafe Tablet

How Metosafe Tablet works

All substitutes for Metosafe 50mg Tablet

Metopole 50 Tablet

betalOC 50mg Tablet

MetoLAR 50 Tablet

Metapro 50 Tablet

Xmbeta 50mg Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

What is the difference between metoprolol succinate and Metosafe 50mg Tablet?

Is Metosafe 50mg Tablet effective?

Which is better, Metosafe 50mg Tablet or metoprolol succinate?

Can I take alcohol while on treatment with Metosafe 50mg Tablet?

Can you switch from Metosafe 50mg Tablet to Metoprolol Succinate?

When should you not take Metosafe 50mg Tablet?

What should I avoid while taking Metosafe 50mg Tablet?

Can I use Metosafe 50mg Tablet in pregnancy?

Can Metosafe 50mg Tablet cause low blood potassium levels (hypokalemia)?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Kidney Function Test

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

Related/Popular tests