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Metalactone 5mg/50mg Tablet

Metolazone (5mg)+ Spironolactone (50mg)

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Metalactone 5mg/50mg Tablet is a combination of two medicines used to treat hypertension (high blood pressure). It reduces the excess fluid levels in your body while maintaining potassium balance.

Written By Dr. Swati Mishra, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 12 Oct 2026 | 01:03 AM (IST)

₹46.6 MRP ₹51.249% off

(Inclusive of applicable taxes)

Gurgaon

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General Information

Contains

Metolazone (5mg)+ Spironolactone (50mg)

Marketer

Centaur Pharmaceuticals Pvt Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

It is best to take Metalactone 5mg/50mg Tablet in the morning along with food in order to avoid frequent urination at night time. For better results, it is suggested to take it at the same time every day. The dose and how often you take it depends on what you are taking it for. Your doctor will decide how much you need to improve your symptoms. You should take this medicine for as long as it is prescribed for you.

Diarrhea, stomach upset, and glucose intolerance are very common side effect of this medicine. It might lower down the electrolytes level like sodium, potassium, and magnesium in the blood. Hence, regular monitoring of kidney function, blood pressure, and electrolytes are important while using this medicine. It might cause dizziness or tiredness if happens rise slowly from sitting position or avoid driving.

Before taking this medicine, tell your doctor if you have any liver or kidney disease. Inform your doctor if you are pregnant. You should also let your healthcare team know all other medicines you are taking as they may affect, or be affected by this medicine.

Uses of Metalactone Tablet

Hypertension (high blood pressure)

Benefits of Metalactone Tablet

Hypertension (high blood pressure)
Metalactone 5mg/50mg Tablet relaxes the blood vessels so that blood can flow more easily around your body. It also eliminates excess water from the body and increases urine output. This maintains balance of electrolytes (like potassium), lowers your blood pressure and reduces your risk of having a stroke, a heart attack, or kidney problems in the future. You do not usually feel any direct benefit from taking this medicine, but it works in the long term to keep you well. You should take it regularly as prescribed for this medicine to be most effective, even if you feel better.

Side effects of Metalactone Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Metalactone

Diarrhea
Upset stomach
Glucose intolerance
Breast enlargement in male
Irregular menstrual cycle
Increased blood lipid level
Increased uric acid level in blood
Electrolyte imbalance
Impotence

How to use Metalactone Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Metalactone 5mg/50mg Tablet should be taken with or after food.

How Metalactone Tablet works

Metalactone 5mg/50mg Tablet is a combination of two diuretics: Metolazone and Spironolactone.

Quick tips

You have been prescribed Metalactone 5mg/50mg Tablet for the treatment of high blood pressure.
Monitor your blood pressure after starting Metalactone 5mg/50mg Tablet and notify your doctor if it does not lower down.
Your doctor may get regular tests done to monitor the level of urea and lipid in your blood.
Metalactone 5mg/50mg Tablet helps you to lose water via urination. If, however, you lose too much fluid, you may become dehydrated. This will make you feel thirsty and make your skin look and feel dry. Let your doctor know if this happens, as your dose may need to be adjusted.
Avoid taking anti-inflammatory medicines such as Ibuprofen along with this medicine without consulting your doctor.
Lifestyle changes like a low-sodium diet, exercise, and not smoking may help this medicine work better.

Safety advice

Alcohol

CAUTION

Alcohol should be used with caution while taking Metalactone 5mg/50mg Tablet.

Pregnancy

CONSULT YOUR DOCTOR

Metalactone 5mg/50mg Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

CONSULT YOUR DOCTOR

Metalactone 5mg/50mg Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

UNSAFE

Metalactone 5mg/50mg Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
As Metalactone 5mg/50mg Tablet may cause drowsiness, dizziness, blurred vision, or lightheadedness and this may affect your ability to drive.

Kidney

CAUTION

Metalactone 5mg/50mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Use of Metalactone 5mg/50mg Tablet is not recommended in patients with severe kidney disease.

Liver

CAUTION

Metalactone 5mg/50mg Tablet should be used with caution in patients with severe liver disease. Dose adjustment may be needed.

Fact Box

Habit Forming

Therapeutic Class

CARDIAC

Related lab tests

Kidney Function Test

References

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Centaur Pharmaceuticals Pvt Ltd
Address: CENTAUR HOUSE, Near Grand Hyatt, Vakola ,Santacruz – East, Mumbai – 400 055, India.

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Home

Cardiac

Combination Of Two Diuretics

Metalactone 5mg/50mg Tablet

Metalactone 5mg/50mg Tablet

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Metalactone Tablet

Benefits of Metalactone Tablet

Side effects of Metalactone Tablet

How to use Metalactone Tablet

How Metalactone Tablet works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Fact Box

Habit Forming

Therapeutic Class

Related lab tests

Kidney Function Test

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

Related/Popular tests