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Melalite Plus Cream is a prescription medicine used to treat melasma. It helps in quick skin renewal. This provides relief from redness, swelling, and itching associated with the condition.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 07 Jan 2026 | 03:31 PM (IST)
₹110 MRP ₹121.139% off 
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Melalite Plus Cream image
Melalite Plus Cream image

Product introduction

Melalite Plus Cream is for external use only. Use it in the dose and duration as advised by your doctor. Wash your hands before using this medicine. It is advised to check the label for directions before use.


There is limited data on the side effects of Melalite Plus Cream. Let your doctor know if you experience any symptoms while applying Melalite Plus Cream, like application site irritation or any other allergic reaction. They may be able to suggest ways to treat or manage the side effects.


Before using Melalite Plus Cream, inform your doctor about any skin conditions, allergies, or ongoing treatments. Avoid applying Melalite Plus Cream to broken, infected, or severely damaged skin unless directed by a doctor. Do not use it if you are allergic to any of its ingredients. Keep it away from the eyes, mouth, and sensitive areas.

Uses of Melalite Plus Cream

  • Melasma

Benefits of Melalite Plus Cream

Melasma
Melasma is a common skin problem that causes dark, discolored patches on your skin primarily on the face. It frequently occurs during pregnancy and menopause. Melalite Plus Cream helps to lighten these dark patches by reducing the production of melanin (natural skin pigment). It lightens skin color and gives a smoother-looking skin. Melalite Plus Cream also reduces any swelling, redness and itchiness especially if you have a sensitive skin. This helps boost your self-esteem and confidence as your appearance changes. Keep using it for as long as it is prescribed to get the full benefits.

Side effects of Melalite Plus Cream

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Melalite Plus
  • Limited data available

How to use Melalite Plus Cream

This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the cream. Wash your hands after applying, unless hands are the affected area.

How Melalite Plus Cream works

Melalite Plus Cream is a combination of three medicines: Hydroquinone, Tretinoin, and Hydrocortisone, which treat melasma (dark spots on skin). Hydroquinone is a skin-lightening medicine. It reduces the amount of skin pigment (melanin) that causes the darkening of the skin. Tretinoin is a form of vitamin A that helps the skin to renew itself more quickly. Hydrocortisone is a steroid that blocks the production of certain chemical messengers (prostaglandins) that make the skin red, swollen, and itchy.

All substitutes for Melalite Plus Cream

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

  • Along with applying Melalite Plus Cream, wear long-sleeved clothing, sunglasses, and a hat whenever you step outside in the hot sun for better protection.
  • Do not cover the area being treated with airtight dressings such as bandages unless directed by a doctor.
  • Use moisturizer regularly to overcome skin dryness during treatment.
  • You may also use certain safe cosmetics (after consulting with your doctor) to lighten pigmentation.
  • Before using Melalite Plus Cream, inform your doctor if you have any skin problems or are applying any other medicines to your skin.

Safety advice

Alcohol

Alcohol

No interaction found/established
Pregnancy

Pregnancy

UNSAFE
Melalite Plus Cream is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.
Breast feeding

Breast feeding

SAFE IF PRESCRIBED
Melalite Plus Cream may be safe to use during breastfeeding. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Driving

Driving

No interaction found/established
Kidney

Kidney

No interaction found/established
Liver

Liver

No interaction found/established

Frequently asked questions

The exact time Melalite Plus Cream takes to show results is not known. However, you may expect improvement in your skin condition in a few weeks to months. The full benefit may take up to several months. Always follow your doctor's advice for safer and faster results.
You can use moisturizer to manage skin dryness. You should wait at least 20 minutes after applying Melalite Plus Cream. It is better and safer to choose fragrance-free, non-comedogenic formulas in moisturizer. You can also ask your doctor for a recommendation for moisturizer.
Use Melalite Plus Cream as often as prescribed by your doctor, who may recommend applying it at night. Take a small amount and gently spread it over the affected area. Avoid contact with the eyes, mouth, and broken skin. To prevent skin darkening, apply sunscreen with SPF 30 or higher during the day.
You may stop the Melalite Plus Cream treatment after achieving desired results or if unusual reactions occur, such as mild redness, irritation, and other difficulties. You should follow and use Melalite Plus Cream as directed by your dermatologist/doctor.
You should include antioxidant foods like berries, leafy greens, and nuts in your daily diet to support skin health. You should keep a check on your water intake to maintain skin elasticity. Also, do not expose your skin to excessive heat/sun. Try to limit exfoliation to stop excessive peeling.

Fact Box

Habit Forming

No

Therapeutic Class

DERMA
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User feedback

Melasma
50%
Others
50%
Average
100%
No Side Effect
100%
With or without food
100%
Expensive
67%
Average
33%
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Abbott
Address: 16th Floor, Godrej BKC, Plot – C, “G” Block, Bandra-Kurla Complex, Bandra (East), Mumbai – 400 051, India

Vendor Details

Country of origin: India
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