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MAHAGESIC PLUS TABLET

Tablet
Rs.23.50for 1 strip(s) (10 tablets each)
1
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Composition FOR MAHAGESIC PLUS

Diclofenac(500mg),Paracetamol(325mg),Famotidine(20mg)

food interaction for MAHAGESIC PLUS

alcohol interaction for MAHAGESIC PLUS

pregnancy interaction for MAHAGESIC PLUS

lactation interaction for MAHAGESIC PLUS

food
alcohol
pregnancy
lactation
There is no data available. Please consult doctor before consuming the drug.
Mahagesic plus tablet may cause excessive drowsiness and calmness with alcohol.
Taking diclofenac with alcohol can increase your risk of stomach bleeding.
Taking a large amount of alcohol can increase acidity and cause acid reflux in the food pipe causing heartburn. This would decrease the effect of this drug and can aggravate your underlying condition.
UNSAFE
Mahagesic plus tablet is unsafe to use during pregnancy.
There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening situations. Please consult your doctor.
WEIGH RISKS VS. BENEFITS
Unknown. Human and animal studies are not available. Please consult your doctor.

SALT INFORMATION FOR MAHAGESIC PLUS

Diclofenac(500mg)

Uses

Diclofenac is used in fever, headache, arthralgia, myalgia, dental pain, post operative pain, pain during menstruation, osteoarthritis, rheumatoid arthritis, ankylosing spondylitis and gout.

How it works

Diclofenac is a non-steroidal anti-inflammatory drug (NSAID). It works by blocking the release of certain chemical messengers that cause fever, pain and inflammation (redness and swelling).

Common side effects

Paracetamol(325mg)

Uses

Paracetamol is used in fever, headache, pain during menstruation, arthralgia, myalgia, dental pain and post operative pain.

How it works

Paracetamol blocks the release of certain chemical messengers in the brain that is responsible for pain and fever.

Common side effects

Allergic reaction, Liver damage
Famotidine(20mg)

Uses

Famotidine is used in the treatment of acidity, heartburn, intestinal ulcers and stomach ulcers.

How it works

Famotidine lowers the acid production in the stomach.

Common side effects

Headache, Muscle pain, Fatigue, Diarrhoea, Drowsiness, Constipation

SUBSTITUTES FOR MAHAGESIC PLUS

No substitutes found

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Expert advice FOR MAHAGESIC PLUS

  • Diclofenac should be taken with food or immediately after meals.
  • Take the medicine with food to avoid stomach upset.
  • Do not take antacids withh magnesium as they can interact with the drug.
  • Do not take diclofenac, If  you are allergic to diclofenac.
  • Do not drink alcohol while takig this drug.
  • Do not drive or use any tools or machines, if you feel dizzy, tired, have a headache or get blurred vision after taking diclofenac.

Frequently asked questions FOR MAHAGESIC PLUS

Diclofenac

Q. Is diclofenac a painkiller?
Yes, diclofenac is a painkiller. It is a nonsteroidal anti-inflammatory drug (NSAID) which is used for conditions like rheumatoid arthritis, osteoarthritis, low back pain, migraine attacks, acute gout, ankylosing spondylitis, Control of pain and inflammation in orthopedic, dental and other minor surgery and other painful conditions of bone and muscles. However, it is a prescription drug and should only be taken as per the advice of the doctor.
Q. Is diclofenac safe in asthma?
Diclofenac may worsen the symptoms of asthma in some patients already suffering from asthma. Talk to your doctor before taking diclofenac if you are suffering from asthma or you have a history of asthma.
Q. Is diclofenac banned in India?
No, diclofenac is not banned in India. However, it is a prescription drug and should be taken only when advised by your doctor.
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Q. Is diclofenac a controlled substance?
Diclofenac is not a controlled substance as it does not have the potential for abuse or addiction.
Q. Does diclofenac increase blood pressure?
Diclofenac does not have any effect on blood pressure in normal individuals. However, it can decrease the effect of medicines which are being given for treatment of high blood pressure (antihypertensives). Please consult your doctor before taking diclofenac if you are already suffering from high blood pressure and you are taking medicines for its treatment.
Q. Is diclofenac nephrotoxic (harmful to kidney)?
Diclofenac can interfere with normal kidney function can cause kidney damage when taken at larger doses for a longer duration. Patients should follow the advice of the doctor regarding the dose and duration for which diclofenac should be taken.
Q. Can I take diclofenac for sore throat?
No, diclofenac is not indicated for sore throat. It is a pain-killer.
Q. Can I take diclofenac for period pain?
No, diclofenac is not indicated for dysmenorrhea (pain during menstruation). It is a pain-killer given to reduce pain associated with muscles and bone.
Q. Can I take diclofenac for a toothache?
Diclofenac can be taken for dental pain (toothache). However, please consult your doctor as there could be an underlying infection or other problem which needs to be diagnosed before starting the treatment.
Q. Can I take diclofenac for a headache?
Diclofenac can be taken for headache. However, it is important to know the cause of headache before starting the treatment especially if the frequency is very high. Please consult your doctor.
Q. Can I take diclofenac for back pain?
Diclofenac can be taken for back pain as it can be used for pain involving muscles and bone. However, it is important to know the cause of back pain before starting the treatment. Please consult your doctor.
Q. Can I take diclofenac for neck pain?
Diclofenac can be taken for neck pain if it is related to muscle and bones. However, it should be taken only when advised by your doctor.
Q. Can I take diclofenac for stomach pain?
Diclofenac is not indicated for stomach pain. It is mainly indicated for relieving musculoskeletal pain, consult a doctor if you have stomach pain, as it could be due to some underlying condition which needs to be diagnosed, before taking any medicine, including a painkiller.
Q. Can I take diclofenac for gout?
Diclofenac can be taken to reduce pain in gout, especially when there is acute gout (sudden painful condition). However, its usefulness in chronic gout is limited. Consult your doctor for the right treatment of gout as the medicines should be taken only after it is diagnosed by a doctor.
Q. Can I take diclofenac for sciatica?
Diclofenac is indicated for the relief of pain in low back pain and sciatica. However, you should consult a doctor before taking the drug.
Q. Can I take diclofenac for muscle pain?
Diclofenac can be taken for muscle pain as it helps in reducing pain. It is a prescription drug and should only be taken if when advised by a doctor.
Q. Is diclofenac safe in pregnancy?
Diclofenac can cause harmful effects during pregnancy and to the growth of the fetus (unborn child). It is not recommended to be used during pregnancy. Consult your doctor regarding the use of the drug during pregnancy as you may need to discontinue the medicine or stop breastfeeding.
Q. Is diclofenac safe?
Diclofenac is safe to use if taken in prescribed doses for a prescribed duration as advised by your doctor.
Q. Is diclofenac a sulfa drug?
No, diclofenac is not a sulfa drug. It a non-steroidal anti-inflammatory drug (NSAID).
Q. Is diclofenac safe during breastfeeding?
Diclofenac is known to be passed in the breast milk in small amounts. So, it should not be taken during breastfeeding. Consult your doctor if you are breastfeeding and you have to take this medicine.
Q. Is diclofenac safe in diabetes?
Diclofenac is not known to affect blood sugar levels. However, in diabetics, the drug should be taken carefully as it can increase the risk of cardiovascular diseases also. Consult your doctor before taking diclofenac if you are a diabetic and you have to take it for a long time.
Q. Does diclofenac reduce menstrual flow?
Diclofenac is not known to reduce menstrual flow. If you are experiencing any change in the menstrual flow after taking diclofenac, please consult your doctor.
Q. Does diclofenac reduce fever?
Yes, diclofenac can reduce fever. However, diclofenac in its analgesic (pain-relieving) dose is not indicated for fever. Please consult your doctor for the proper diagnosis and right treatment for your fever.
Q. Does diclofenac induce sleep?
Diclofenac in rare cases can cause somnolence (increased desire to sleep). If you experience any disturbance in your sleep pattern while taking diclofenac, please consult your doctor.
Q. Does diclofenac expire?
Yes, diclofenac like any other medicine expires. It is not recommended to use the drug after its expiry date. Please check the pack before using the medicine.
Q. Does diclofenac cause weight gain?
Diclofenac is not seen to cause weight gain. It can, however, rarely cause edema (swelling) due to fluid retention. If you experience any noticeable change in weight while taking the drug, consult your doctor.
Q. Does diclofenac have aspirin in it?
No, diclofenac does not contain aspirin. They are different medicines belonging to the same class of nonsteroidal anti-inflammatory drugs (NSAIDs).
Q. Does diclofenac contain paracetamol?
No, diclofenac does not contain paracetamol. They are different medicines belonging to the same class of nonsteroidal anti-inflammatory drugs (NSAIDs).
Q. Does diclofenac contain ibuprofen?
No, diclofenac does not contain ibuprofen. They are different medicines belonging to the same class of nonsteroidal anti-inflammatory drugs (NSAIDs).
Q. Does diclofenac cause constipation?
Constipation is a very rare side effect with diclofenac. If you experience constipation while taking diclofenac, please consult your doctor.
Q. Can I take diclofenac with etoricoxib?
Both diclofenac and etoricoxib are the non-steroidal anti-inflammatory drug (NSAIDs) and can be given together. No interactions have been reported between the two. However, there are interactions reported between diclofenac and other NSAIDs. Please consult your doctor before taking the two medicines together.
Q. Can I take diclofenac with paracetamol?
Diclofenac is a non-steroidal anti-inflammatory drug (NSAID), and when given along with other NSAIDs like paracetamol, it can increase the risk of stomach bleeding and ulceration. Consult your doctor before taking the two medicines together.
Q. Can I take diclofenac with naproxen?
Diclofenac is a non-steroidal anti-inflammatory drug (NSAID), and when given along with other NSAIDs like naproxen, it can increase the risk of stomach bleeding and ulceration. Consult your doctor before taking the two medicines together.
Q. Can I take diclofenac with ibuprofen?
Diclofenac is a non-steroidal anti-inflammatory drug (NSAID), and when given along with other NSAIDs like ibuprofen, it can increase the risk of stomach bleeding and ulceration. Consult your doctor before taking both the drugs together.
Q. Can I take diclofenac with hydrocodone?
No interactions have been clinically observed between diclofenac and hydrocodone. However, interactions may occur. Please consult your doctor before taking both the medications together.
Q. Can I take diclofenac with amoxicillin?
Diclofenac and amoxicillin are not known to have any clinically meaningful interactions when taken together. However, interactions may occur. Please consult your doctor before taking both the medications together.
Q. Can I take diclofenac with meloxicam?
Diclofenac is a non-steroidal anti-inflammatory drug (NSAID), and when given along with other NSAIDs like meloxicam, it can increase the risk of stomach bleeding and ulceration. Consult your doctor before taking both the drugs together.

Paracetamol

Q. Is paracetamol a non-steroidal anti-inflammatory drug (NSAID)?
Paracetamol is a non-steroidal anti-inflammatory drug (NSAID) with analgesic (pain-killer) and anti-pyretic (anti-fever) properties. It is useful in relieving mild to moderate pain and febrile (fever) conditions.
Q. Is paracetamol available in India?
Paracetamol (also known as acetaminophen) is available in India.
Q. Can I take paracetamol for headache?
Paracetamol is a pain killer and can help in the relief of mild to a moderate headache. For a severe headache and headache not getting relieved with paracetamol, talk to your doctor.
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Q. Is paracetamol a painkiller?
Paracetamol is a non-steroidal anti-inflammatory drug (NSAID), a painkiller used to relieve mild to moderate pain.
Q. Does paracetamol make you drowsy (sleepy)?
Paracetamol does not make you drowsy (sleepy).
Q. Can I take paracetamol with ibuprofen?
No side effects have been reported when paracetamol is used with ibuprofen. However, paracetamol is a non-steroidal anti-inflammatory drug (NSAID), and when given along with other NSAIDs like ibuprofen, it can increase the risk of gastritis, stomach bleeding, and ulceration when used for a long time. Talk to your doctor before taking the two medicines together.
Q. Does paracetamol cause death?
Paracetamol on overdose can severely damage the liver and cause death. Always consult your doctor before using paracetamol and it should be consumed in the dose as advised by your doctor.
Q. Can paracetamol make babies/ toddlers sleep when used for teething pain?
Paracetamol can help to relieve pain in infants and children, it does not make them sleep.
Q. Can I take paracetamol for cold?
Paracetamol can help in the relief of mild to moderate headache and fever associated with a cold. Talk to your doctor if you have a high fever and for the relief of other associated sign and symptoms with cold.
Q. Can I take paracetamol for stomach ache?
Paracetamol should not be taken for stomach ache. You must consult your physician for the relief of stomach pain as the relief of pain can mask the underlying disease problem.
Q. Can I take paracetamol for toothache?
Paracetamol is a pain killer and can help in the relief of mild to moderate toothache.
Q. Can I take paracetamol for period pains?
Paracetamol is a pain killer and can help in the relief of mild to moderate pain associated with periods also known as dysmenorrhoea (painful menstruation).
Q. Can I take paracetamol for headache during pregnancy?
Ideally, you should avoid taking any type of medicine during pregnancy. Mild pains generally do not need any treatment, still if there is a need for a pain killer, take the lowest possible dose after consultation with your physician or gynecologist. Studies in human pregnancy have shown no effects due to paracetamol used in the recommended dosage.
Q. Can I take paracetamol for fever?
Yes, paracetamol is an anti-pyretic drug (drug for relieving fever) and can be used for relieving mild to moderate fever. However, it is advisable that you talk to your doctor before taking any medicine for your fever.
Q. Can I take paracetamol with cetirizine?
Yes, paracetamol can be taken with cetirizine as there are no interactions seen when both are used together, but it is always safe to consult your doctor before taking any two drugs together.
Q. Can I take paracetamol with food or milk?
It is safe to take paracetamol with food or milk.
Q. Can I take paracetamol with high blood pressure?
Paracetamol can be taken if you have high blood pressure. However, it is advised to take it only after consulting your doctor as it belongs to the group of non-steroidal anti-inflammatory drugs (NSAIDs) and these medicines can cause decrease the effect of drugs used for the treatment of hypertension (high blood pressure). Talk to your doctor before taking it if you are also taking any treatment for high blood pressure.
Q. Can I take paracetamol with azithromycin?
Paracetamol and azithromycin are not known to have any clinically meaningful interactions when taken together. However, interactions may occur. Please consult your doctor before taking both the medications together.
Q. Can I take paracetamol with metronidazole?
Paracetamol and Metronidazole are not known to have any clinically meaningful interactions when taken together. However, interactions may occur. Please consult your doctor before taking both the medications together.
Q. Can I take paracetamol with homeopathic medicine?
Ask your doctor before taking paracetamol with homeopathic medicine as there is no data available on this.
Q. Is paracetamol safe to use?
Paracetamol is safe to use in the dose as recommended by the physicians. Use more than recommended doses can do serious harm.
Q. Is paracetamol an antibiotic?
Paracetamol is not an antibiotic. It's an analgesic (pain-killer) and anti-pyretic (for the relief of fever).
Q. Can I take paracetamol with naproxen?
Paracetamol and naproxen are not known to have any clinically meaningful interactions when taken together. However, interactions may occur. Please consult your doctor before taking both the medications together.
Q. Can I take paracetamol with tramadol?
Paracetamol and tramadol are not known to have any clinically meaningful interactions when taken together. However, interactions may occur. Please consult your doctor before taking both the medications together.
Q. Can I take paracetamol with erythromycin?
Paracetamol and erythromycin are not known to have any clinically meaningful interactions when taken together. However, interactions may occur. Please consult your doctor before taking both the medications together.
Q. Is paracetamol banned?
Paracetamol (acetaminophen) is not a banned drug. It is available without a prescription.
Q. Is paracetamol an analgesic?
Yes, paracetamol is an analgesic (painkiller) medicine and can be used for the relief of pain, for example, toothache, headache, and sprain.
Q. Can I take paracetamol with codeine?
Paracetamol and codeine are not known to have any clinically meaningful interactions when taken together. However, interactions may occur. Please consult your doctor before taking both the medications together.
Q. Does paracetamol have side effects?
Paracetamol is quite safe for short term use. It has side effects if taken in more than the prescribed dose. Immediately consult a doctor if there is nausea, stomach pain, loss of appetite, dark colored urine, clay colored stools or jaundice as it could be due to an overdose of paracetamol.
Q. Does paracetamol affect the liver?
Use of paracetamol above the recommended doses can cause serious liver damage. If you are taking paracetamol from a long time and you have nausea, stomach pain, loss of appetite, dark colored urine, clay colored stools or jaundice, immediately consult your doctor as this could be due to an underlying liver damage from paracetamol.
Q. Does paracetamol cure sore-throat?
Paracetamol does not cure sore-throat but it can help in relieving fever associated with cold, flu or sore-throat.
Q. Does paracetamol help a cough?
No, paracetamol does not help in the relief of cough.
Q. Does paracetamol contain alcohol?
No, paracetamol does not contain alcohol.
Q. Can I take paracetamol with warfarin?
Effect of warfarin and other coumarins (anticoagulants) may be increased with a long and regular use of paracetamol with increased risk of bleeding. Occasional doses have no significant effect. Talk to your doctor before taking both the medicines together.
Q. Can I take paracetamol with aceclofenac?
Paracetamol and aceclofenac are not known to have any clinically meaningful interactions when taken together. However, interactions may occur. Please consult your doctor before taking both the medications together.
Q. Can I take paracetamol with amoxicillin?
Paracetamol and amoxicillin are not known to have any clinically meaningful interactions when taken together. However, interactions may occur. Please consult your doctor before taking both the medications together.

Famotidine

Q. What is the difference between famotidine and pantoprazole?
Famotidine is an H2 histamine receptor blocker whereas pantoprazole is a proton pump inhibitor. Pantoprazole is more potent at inhibiting gastric acid production compared to famotidine and also its effect lasts for a long time.
Q. How is famotidine different from cimetidine?
Both famotidine and cimetidine lower gastric acid secretion by blocking the H2 receptor in the stomach. However, famotidine is longer acting, more efficacious, and has very fewer side effects when compared to cimetidine.
Q. Can I take famotidine with ibuprofen?
Famotidine can be taken with ibuprofen as no harmul effects have been seen when they are used together. Ibuprofen is a pain killer and belongs to the group of NSAIDs (non-steroidal anti-inflammatory agents) and you should be careful while taking NSAIDs as they are strong gastric acid stimulators and would increase the gastric acid secretion and further worsen your underlying condition.
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Q. Would there be a change in the dose of famotidine in patients undergoing dialysis?
In patients with severe renal failure, a lowering of a dose of famotidine to one-third is recommended, however, patients who undergo dialysis do not need to add a dose even if there is a considerable variation in the clearance of the drug from the body in these patients.
Q. Can I take famotidine with aspirin?
Famotidine can be taken with aspirin as no harmful effects have been seen when they are used together. However, aspirin is a pain killer and belongs to the group of NSAIDs (non-steroidal anti-inflammatory agents) which are strong gastric acid stimulators and can worsen your underlying condition by increasing gastric acid secretion.
Q. Why does famotidine cause dizziness?
Dizziness is seen in >1% pf patients who use famotidine. The exact mechanism of how famotidine causes dizziness is not known. However, the suggested mechanism is through blockade of H2 receptor located in the brain (cerebral cortex and corpus striatum). Do not drive or use any machinery in case you feel dizzy while taking famotidine.
Q. What is the role of famotidine before surgery?
Famotidine is given as a part of pre-anesthetic medication before surgery to decrease the gastric acid secretion so that gastric acid is not aspirated into the lungs during surgery.
Q. What are the side effects of intravenous famotidine?
Headache, dizziness, diarrhea, dry mouth, nausea, vomiting, constipation, abdominal discomfort, fatigue, and urticaria are some of the side effects reported with the use of intravenous famotidine.
Q. When does famotidine start working?
When taken orally, famotidine is rapidly and incompletely absorbed and it starts working in approximately 1-3 hours and when given intravenous, it starts working in 30 minutes and the effect stays for 10-12 hours.
Q. Can I take famotidine with ranitidine?
Both famotidine and ranitidine lower gastric acid secretion by blocking the H2 receptor in the stomach. They are not used together as they have a similar action and use and when used together, there could be an increased risk of side effects.
Q. What is the role of famotidine in critically ill patients?
Famotidine may be used in critically ill patients to reduce the risk of acute gastrointestinal bleeding, ulceration and gastric acid secretion, so as to further prevent the risk of acid aspiration.
Q. What is the best time to take famotidine?
The best time to take famotidine when given once a day is before going to bed, as it is very effective in reducing the night time acid secretion. If you are asked to take this medicine twice daily, then it can be taken once in the morning and other in the evening.
Q. What is the difference between famotidine and esomeprazole?
Famotidine is an H2 histamine receptor blocker whereas esomeprazole is a proton pump inhibitor. Esomeprazole is more potent at inhibiting gastric acid production compared to famotidine and also its effect lasts for a long time.
Q. What are the side effects of famotidine in elderly?
Headache and dizziness are common side effects reported with famotidine use. Dry mouth, nausea, vomiting, constipation, abdominal discomfort, fatigue, and urticaria are some of the other adverse effects reported.
Q. Is famotidine an over the counter product?
Famotidine is not available as an over the counter (OTC) product. It is a prescription medicine and is available when prescribed by a doctor.
Q. Are there any withdrawal symptoms associated with the use of famotidine?
Famotidine is not seen to be associated with any withdrawal symptoms. In treatment-withdrawal studies of famotidine, no significant withdrawal symptoms were observed after discontinuing the medication.
Q. Why is famotidine added to total parenteral nutrition?
Patients on total parenteral nutrition are prone to increased secretion of gastric acid in the absence of food. H2 receptor blockers like famotidine is given in these patients to reduce acid secretion and to prevent gastric ulcers.
Q. Where and how is famotidine absorbed and metabolized?
Famotidine is absorbed from the intestine and is metabolized in the liver where it gets degraded to an inactive sulfoxide metabolite.
Q. What are the side effects of famotidine seen in infants?
Irritability, lethargy, diarrhea, dry mouth, vomiting, constipation, abdominal discomfort, fatigue, and urticaria are some of the side effects reported with the use of famotidine in infants (children less than 1 year of age).
Q. Why is famotidine used in cancer patients?
Famotidine may be used for multiple reasons in cancer patients. It can be used to reduce gastric ulceration, bleeding and gastric acid volume in patients undergoing chemotherapy to prevent aspiration. Some studies also show evidence that famotidine can potentiate white blood cell against cancer cells and can be helpful in the treatment of cancer.
Q. When does famotidine expire?
Yes, famotidine does expire. Please check the expiry date written on the pack and it refers to the last day of that month. Do not use omeprazole after the expiry date.

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Content on this page was last updated on 08 March, 2017, by Dr. Varun Gupta (MD Pharmacology)