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Mahagesic Plus Tablet

Written By Dr. Subita Alagh, BDS
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS
Last updated on 02 Feb 2026 | 01:08 PM (IST)
Mahagesic Plus Tablet is a pain-relieving medicine. It is used to treat pain and inflammation in conditions like rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis. It is also used to relieve muscle pain, back pain, toothache, or pain in the ear and throat.
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₹20.1 MRP ₹22.039% off 
As per Ministry of Health and Family Welfare
 
 
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General Information

Contains

Diclofenac (500mg)+ Paracetamol (325mg)+ Famotidine (20mg)

Marketer

Mankind Pharma Ltd

Storage

Store below 30°C
The content is shown in English
Mahagesic Plus Tablet image
Mahagesic Plus Tablet image

Product introduction

Mahagesic Plus Tablet should be taken with food. This will prevent you from getting an upset stomach. The dose will depend on what you are taking it for and how well it helps your symptoms. You should take it as advised by your doctor. Do not take more or use it for a longer duration than recommended by the doctor.

The most common side effects of this medicine include nausea, vomiting, heartburn, stomach pain, diarrhea, and loss of appetite. If any of these side effects bother you or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the side effects.

Before taking it, you should let your doctor know if you have a history of ulcer or bleeding in your stomach, high blood pressure, or have any trouble with your heart, kidneys, or liver. Let your doctor also know about all the other medicines you are taking because they may affect, or be affected by, this medicine.

Pregnant or breastfeeding women should consult their doctor before starting treatment. You should also avoid drinking alcohol while you are taking this medicine, as alcohol can cause excessive drowsiness.

Uses of Mahagesic Plus Tablet

Benefits of Mahagesic Plus Tablet

Pain relief
Mahagesic Plus Tablet relieves pain, reduce swelling and ease inflammation in conditions like rheumatoid arthritis, osteoarthritis and ankylosing spondolytis. It also gives relief from muscle and back pain, toothache, or pain in the ear and throat. It works by reducing substances in the body that causes pain and swelling. Mahagesic Plus Tablet contains an antacid that prevents acidity that may occur due to this medicine. Take it as prescribed to get the most benefit. This will help you to go about your daily activities more easily and have a better, more active, quality of life.

Side effects of Mahagesic Plus Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Mahagesic Plus
  • Nausea
  • Vomiting
  • Diarrhea
  • Constipation
  • Loss of appetite

How to use Mahagesic Plus Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Mahagesic Plus Tablet should be taken with or after food.

How Mahagesic Plus Tablet works

Mahagesic Plus Tablet is a combination of three medicines: Diclofenac, Paracetamol, and Famotidine which relieve pain and fever. Diclofenac and Paracetamol work by blocking the release of certain chemical messengers in the brain that are responsible for pain and fever. Famotidine is an H2 blocker (type of antacid). It works by reducing the amount of acid in the stomach which helps to get relief of acid-related indigestion and heartburn.

Quick tips

  • Mahagesic Plus Tablet is used to treat various painful conditions.
  • Do not take any other medicines containing Paracetamol in it without consulting your doctor.
  • Stick to simple meals and avoid spicy rich food in order to avoid feeling sick (nausea).
  • Drink plenty of water while taking Mahagesic Plus Tablet.
  • If you have asthma, symptoms such as wheeze or breathlessness might become worse by Mahagesic Plus Tablet. If this happens to you, consult your doctor immediately.

Safety advice

Alcohol

Alcohol

UNSAFE
Do not drink alcohol while you are taking this medicine. Mahagesic Plus Tablet may cause excessive drowsiness when taken with alcohol.
Pregnancy

Pregnancy

UNSAFE
Mahagesic Plus Tablet is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Mahagesic Plus Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving

Driving

UNSAFE
Mahagesic Plus Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

CAUTION
Mahagesic Plus Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Liver

Liver

UNSAFE
Mahagesic Plus Tablet is unsafe to use in patients with liver disease and should be avoided.

Frequently asked questions

Mahagesic Plus Tablet is a pain-relieving medicine used for the short-term management of moderate to severe pain, especially when it is associated with inflammation. It is often prescribed for conditions like post-operative pain, pain from injuries, arthritis, or severe musculoskeletal pain that is not relieved by simpler painkillers.<br>
Yes. The dextropropoxyphene component of Mahagesic Plus Tablet is an opioid, which can cause significant drowsiness, dizziness, and a feeling of sedation. It is very important that you do not drive, operate heavy machinery, or do anything that requires full mental alertness until you know how this medicine affects you.<br>
Mahagesic Plus Tablet is an oral medicine that you should swallow whole with a full glass of water. It is generally recommended to take this medicine with food, or just after a meal, to help reduce the risk of stomach upset and irritation.<br>
You can expect to start feeling relief from your pain within about 30 to 60 minutes of taking Mahagesic Plus Tablet. The analgesic effects of the medicine will become more noticeable with continued use.<br>
Yes. The dextropropoxyphene in Mahagesic Plus Tablet is an opioid and has the potential to be habit-forming, leading to physical and psychological dependence, especially with prolonged use. It is very important to take it only as prescribed, and for the shortest duration possible.<br>

Fact Box

Habit Forming

No

Therapeutic Class

PAIN ANALGESICS

References

  1. Diclofenac. Rouse Boulevard, Philadelphia: Iroko Pharmaceuticals; 1998 [revised Oct. 2013]. [Accessed 02 Apr. 2019] (online) Available from:
  2. Famotidine. South Granville, New South Wales: Merck Sharp & Dohme Pty., Ltd.; 1996. [Accessed 11 Mar. 2019] (online) Available from:
  3. ScienceDirect. Paracetamol. [Accessed 02 Apr. 2019] (online) Available from:
  4. ScienceDirect. Famotidine. [Accessed 02 Apr. 2019] (online) Available from:
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User feedback

Pain relief
50%
Others
33%
Fever
17%
Average
100%
Vomiting
33%
Nausea
33%
Diarrhea
33%
With food
100%
Expensive
67%
Average
33%
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Mankind Pharma Ltd
Address: 208, Okhla Industrial Estate, Phase III, New Delhi - 110020

Vendor Details

Country of origin: India

Lab tests offered by us

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