Author Details
Written By
Pharm.D
Reviewed By
MBA, MD Pharmacology
Last updated
26 Sep 2025 | 02:27 PM (IST)

We provide you with authentic, trustworthy and relevant information

Want to know more

Have issue with the content?

Report Problem

Luporal Capsule

rx_imgPrescription Required

Product introduction

Luporal Capsule is a prescription medicine which is a combination of two anticancer medicines that is used in the treatment of cancer of the colon and rectum. It prevents the growth and multiplication of cancer cells, thus helps in destroying the tumor.

Luporal Capsule may be taken with or without food. It should be used in the dose and duration as prescribed by your doctor. It is advised to take this medicine at a fixed time.

This medicine should not be taken more than the recommended dose. If you miss any dose, please consult your doctor. It is advised to complete the treatment without any interruption. This medicine is usually well tolerated by patients.

The common side effects of this medicine include nausea, vomiting, hair loss, low number of blood cells (anemia) and a decrease in white blood cell count. The doctor may ask you to undergo a few blood tests before or during the treatment.

Your doctor may prescribe you to undergo blood tests before or during the treatment. You may be given supplements to overcome the deficiency caused by this medicine. It is advised to add more vegetables and fruits in your diet to overcome any such deficiency.

This medicine is not safe to use in pregnancy. Inform your doctor if you are taking any other medicines or if you are breastfeeding. Inform your doctor if you are suffering from any disease. It is strictly advised not to drive or operate heavy machinery while you are on the treatment.


Uses of Luporal Capsule

Benefits of Luporal Capsule

In Cancer of colon and rectum

Luporal Capsule treats cancer of the colon and rectum as well as lowers the risk of developing further cancerous growths. Using this medicine helps you recover more comfortably from chemotherapy. It is usually taken for 28 days (four weeks), followed by a seven day break. The cycle is then repeated. Follow your doctor's advice strictly during the entire treatment. Avoid drinking alcohol or smoking while having this treatment and drink plenty of water to stay hydrated.

Side effects of Luporal Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Luporal

  • Nausea
  • Vomiting
  • Tiredness
  • Mouth sore
  • Sore tongue
  • Stomach pain
  • Diarrhea
  • Loss of appetite
  • Decreased blood cells (red cells, white cells, and platelets)

How to use Luporal Capsule

Take this medicine in the dose and duration as advised by your doctor. Luporal Capsule may be taken with or without food, but it is better to take it at a fixed time.

How Luporal Capsule works

Luporal Capsule is a combination of two medicines: Tegafur and Uracil which treat cancer. They work by interfering with the growth of DNA and RNA of cancer cells by substituting their building blocks. This prevents the cancer cells from growing and multiplying.

Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Luporal Capsule. Please consult your doctor.
Pregnancy
UNSAFE
Luporal Capsule is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Luporal Capsule during breastfeeding is not available. Please consult your doctor.
Driving
UNSAFE
Luporal Capsule may cause side effects which could affect your ability to drive.
Luporal Capsule may make you tired, nauseous or have blurred vision and this may affect your ability to drive.
Kidney
CONSULT YOUR DOCTOR
There is limited information available on the use of Luporal Capsule in patients with kidney disease. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Luporal Capsule in patients with liver disease. Please consult your doctor.

What if you forget to take Luporal Capsule?

If you miss a dose of Luporal Capsule, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Luporal Capsule
₹123.7/Capsule
Tegafi 100mg/224mg Capsule
Intas Pharmaceuticals Ltd
₹120.71/capsule
2% cheaper
Tegasted Capsule
Halsted Pharma Private Limited
₹131.5/capsule
6% costlier

Quick tips

  • Luporal Capsule is used for the treatment of cancer of the colon and rectum.
  • Avoid the use of antacids within 2 hours of taking this medicine.
  • Drink plenty of water every 24 hours after the start of the treatment.
  • You may be at risk of infection so try to avoid crowds or people with colds, and report fever or any other signs of infection immediately to your doctor.
  • To help treat/prevent mouth sores, use a soft toothbrush and rinse your mouth at least 3 times a day with saline water.
  • To reduce nausea, take anti-nausea medications as prescribed by your doctor, and eat small, frequent meals.
  • Eat foods that may help reduce diarrhea and take adequate rest.

Fact Box

Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS

Patient concerns

Is ulcers curable G2 stage of cancer in rectum area
Dr.
Gastroenterology
Needs evaluation Please meet a Gastro surgeon
Colon cancer What treat many I have to give
Dr. Aanchal Maheshwari
Ayurveda
Complete reports along with the patient is need to be seen before starting the treatment

User feedback


FAQs

Who should not take Luporal Capsule?

Individuals should not take Luporal Capsule if they are allergic to tegafur, uracil, 5-fluorouracil (5-FU), or any ingredient in the medicine. It is also not safe for children, teenagers, pregnant women, or breastfeeding mothers.

Can Luporal Capsule cause liver damage?

Yes, Luporal Capsule may cause serious liver problems, including hepatitis and, in rare cases, liver failure. Your doctor may run regular blood tests to check your liver function while you are taking this cancer treatment. If you notice yellowing of the skin or eyes, dark urine, or severe fatigue, seek medical help immediately.

Is diarrhea from Luporal Capsule dangerous?

Diarrhea is a common side effect of Luporal Capsule, but it can become dangerous if severe. If you develop persistent or watery diarrhea, you should stop the medication and contact your doctor right away, as it can lead to dehydration and require medical care.

Can Luporal Capsule affect the heart?

Yes, Luporal Capsule may cause heart problems in some patients, such as chest pain, irregular heartbeat, heart failure, or heart attack. If you already have a heart condition, your doctor will monitor you more closely during treatment.

Is Luporal Capsule safe for elderly patients?

Elderly patients may be at higher risk of side effects from Luporal Capsule because of weaker liver, kidney, or heart function. Doctors usually start older patients on the medicine with extra caution and frequent monitoring.

What are the serious side effects of Luporal Capsule?

Serious side effects of Luporal Capsule include unexplained bleeding or bruising, severe infection, chest pain, breathing problems, confusion, or sudden weakness. Rarely, it can cause life-threatening conditions like liver failure, severe skin reactions, or kidney failure. Contact your doctor immediately if you notice any of these.

Can Luporal Capsule affect my blood counts?

Yes, Luporal Capsule can lower your white blood cells, red blood cells, and platelets, which can make you more prone to infections, anemia, or bleeding. Your doctor will check your blood counts regularly during treatment.

Can I take Luporal Capsule if I have kidney problems?

There is limited experience with Luporal Capsule in patients with kidney problems. Your doctor may prescribe it with caution and monitor your kidney function closely. Report any swelling, decreased urine output, or unusual tiredness to your doctor.

Can Luporal Capsule cause nervous system problems?

In rare cases, Luporal Capsule may affect the nervous system, leading to confusion, memory loss, speech problems, unsteady walking, or nerve pain. Report these symptoms to your doctor right away.

How can Luporal Capsule affect the skin?

Luporal Capsule may sometimes cause skin problems like rashes, itching, eczema, or more serious reactions such as Stevens-Johnson syndrome (a rare but severe skin condition). If you develop blistering, peeling skin, or painful sores, stop the medication and seek emergency care.
Related lab tests

Want to share the information?

Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Central Drugs Standard Control Organisation (CDSCO). [Accessed 23 Apr. 2019] (online) Available from:External Link
  2. Uracil-Tegafur. Bedfordview, South Africa: Bristol-Myers Squibb (Pty) Ltd; 2001. [Accessed 24 Apr. 2019] (online) Available from:External Link

Marketer details

Name: Lupin Ltd
Address: 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India
Country of origin: Taiwan
Expires on or after: April, 2027

A licensed vendor partner from your nearest location will deliver Luporal Capsule. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

MRP1457  15% OFF
1237
Inclusive of all taxes
10.0 capsules in 1 strip
New GST benefit included in this MRP, may differ from label
Get by Wednesday, 8 October
Delivering to:

INDIA’S LARGEST HEALTHCARE PLATFORM

  • 260m+
    Visitors
  • 31m+
    Orders Delivered
  • 1800+
    Cities
Get the link to download App
  • Reliable

    All products displayed on Tata 1mg are procured from verified and licensed pharmacies. All labs listed on the platform are accredited

  • Secure

    Tata 1mg uses Secure Sockets Layer (SSL) 128-bit encryption and is Payment Card Industry Data Security Standard (PCI DSS) compliant

  • Affordable

    Find affordable medicine substitutes, save up to 50% on health products, up to 80% off on lab tests and free doctor consultations.

LegitScript approved
India's only LegitScript and ISO/ IEC 27001:2022 certified online healthcare platform

Access medical and health information

Tata 1mg provides you with medical information which is curated, written and verified by experts, accurate and trustworthy. Our experts create high-quality content about medicines, diseases, lab investigations, Over-The-Counter (OTC) health products, Ayurvedic herbs/ingredients, and alternative remedies.

Order medicines online

Get free medicine home delivery in over 1800 cities across India. You can also order Ayurvedic, Homeopathic and other Over-The-Counter (OTC) health products. Your safety is our top priority. All products displayed on Tata 1mg are procured from verified and licensed pharmacies.

Book lab tests

Book any lab tests and preventive health packages from certified labs and get tested from the comfort of your home. Enjoy free home sample collection, view reports online and consult a doctor online for free.

Consult a doctor online

Got a health query? Consult doctors online from the comfort of your home for free. Chat privately with our registered medical specialists to connect directly with verified doctors. Your privacy is guaranteed.

visamastercardamerican expressrupaynet bankingcash on delivery