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14 Dec 2018 | 04:37 PM (IST)
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Lupizep Plus 25 mg/0.5 mg Tablet


Overview

Uses of Lupizep Plus Tablet

Lupizep Plus Tablet side effects

Common
  • Nausea
  • Vomiting
  • Diarrhea
  • Confusion
  • Memory impairement
  • Uncoordinated body movements
  • Drowsiness
  • Tiredness
  • Anorgasmia (decreased orgasm)
  • Low sexual desire
  • Delayed ejaculation

How to use Lupizep Plus Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Lupizep Plus 25 mg/0.5 mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Lupizep Plus Tablet works

Lupizep Plus 25 mg/0.5 mg Tablet is a combination of two medicines: Paroxetine and Clonazepam which has mood-enhancing and anxiety-lowering effects. Paroxetine is selective serotonin reuptake inhibitor (SSRI) which increases the levels of serotonin, a chemical messenger that improves mood. Clonazepam is a benzodiazepine (BZD) which increases the action of GABA, a chemical messenger that suppresses the abnormal activity of the nerve cells in the brain.

Lupizep Plus Tablet related warnings

Alcohol
CAUTION
Lupizep Plus 25 mg/0.5 mg Tablet may cause excessive drowsiness and calmness with alcohol.
Pregnancy
CAUTION
Lupizep Plus 25 mg/0.5 mg Tablet is highly unsafe to use during pregnancy.
Human and animal studies have shown significant adverse effects on the fetus. Please consult your doctor.
Lactation
CAUTION
Lupizep Plus 25 mg/0.5 mg Tablet is probably unsafe to use during lactation. Limited human data suggest that the drug could represent a significant risk to the baby.
Driving
Lupizep Plus 25 mg/0.5 mg Tablet may cause side effects which could affect your ability to drive.
Kidney
Lupizep Plus 25 mg/0.5 mg Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Lupizep Plus 25 mg/0.5 mg Tablet may not be needed in these patients. Please consult your doctor.
Use of Lupizep Plus 25 mg/0.5 mg Tablet can cause excessive sleepiness in patients with end stage kidney disease.
Liver
CAUTION
Lupizep Plus 25 mg/0.5 mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Lupizep Plus 25 mg/0.5 mg Tablet may be needed. Please consult your doctor.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
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Patient Concerns

Questions Related to Lupizep Plus

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Sir i have taken the medicine of depression tablet ventab 25 mg prponol 10 mg nixodre plus i am feeling very tired and i wanted to concieved as soon as possoble is it write please give advice aboit this. When i have to try to conceive does any side effect on baby please suggest me i have taken these medicine from 3 to 4 month but there is no any improment y health how to overcome from this problem please reply me
Dr. Jyoti Kapoor Madan
Psychiatrist
You shouldn't plan pregnancy while you are on psychotropics, they can harm the foetus, especially during the first three months of conception. Pregnancy can also increase the risk to increasing depression. A reasonable solution is to get adequate treatment and go for psychotherapy, after you have recovered from depression, gradually withdraw medicines and continue therapy before planning conception. For further guidance, visit your psychiatrist.
I am suffering depression from 20 year I am consuming depsonil 25 mg and Trinicalm plus 10 mg but now days there is not good sleep is there any side effect on my health due to consuming medicine for long period
Dr. Jyoti Kapoor Madan
Psychiatrist
All long term medicines need regular monitoring to identify if there are any side effects. The effects and sude effects have to be rationally balanced. Don't continue medicines without follow up with the prescribing psychiatrist for proper monitoring. If you are having trouble sleeping, you may need a change of medication.
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FAQs

Q. Are there any important warnings associated with the use of Lupizep Plus?

Lupizep Plus may increase the suicidal thoughts or actions in some patients, in the first few months of the treatment. Patients having mood or behavioral disorder have a high risk of suicidal thoughts and actions. You should pay close attention and report your doctor of any changes in behavior or mood. Make sure that you visit the doctor for the follow-up appointments as scheduled.

Q. Can I stop taking Lupizep Plus when my symptoms are relieved?

No, you should continue taking Lupizep Plus even if you feel well. If you stop Lupizep Plus suddenly, serious withdrawal symptoms may occur. Your doctor will probably decrease your dose gradually.

Q. How to manage weight gain associated with the use of Lupizep Plus?

There are reports that suggest that the use of Lupizep Plus can cause weight gain. If you keep good eating habits and exercise regularly, you might not gain any weight. It is important to remember that it is easier to stop weight gain than losing increased weight.

Q. Can the use of Lupizep Plus cause sleepiness?

Yes, Lupizep Plus can make you feel sleepy. Avoid driving, operating machinery, working at heights or participating in potentially dangerous activities till you know how this medicine affects you.

Q. Can the use of Lupizep Plus affect my sex life?

The use of Lupizep Plus can affect the sexual life of both men and women. Different sexual problems can occur due to Lupizep Plus like decreased sexual desire, erectile dysfunction (inability to develop or maintain erection during the sexual activity) and inability to reach orgasm. It can also cause a decrease in satisfaction and cause discomfort during intercourse. If you experience these problems, discuss with your doctor.

Q. Can I drink alcohol while taking Lupizep Plus?

No, do not drink alcohol while taking Lupizep Plus. Drinking alcohol can increase the severity of drowsiness or sleepiness caused by Lupizep Plus.

Q. How long does Lupizep Plus take to work?

Everybody responds differently to treatment. In general, it can take several weeks to feel the full benefits of Lupizep Plus, although some people may start to feel better sooner. When taking Lupizep Plus, it is important to give it time to work.

Q. What are the instructions for the storage and disposal of Lupizep Plus?

Keep this medicine in the packet or the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

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Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Paroxetine. Miami, Florida:Noven Therapeutics; 2003 [revised 06-2013]. [Accessed 23 Apr. 2019] (online) Available from:External Link
  2. Clonazepam. Boucherville, Québec: Sandoz Canada Inc.; 2018. [Accessed 23 Apr. 2019] (online) Available from:External Link
  3. Paroxetine. South Ruislip, Middlesex: Aurobindo Pharma - Milpharm Ltd.; 2008 [revised 25 Nov. 2018]. [Accessed 23 Apr. 2019] (online) Available from:External Link
  4. Clonazepam. Boucherville, Québec: Sandoz Canada Inc.; 2018. [Accessed 23 Apr. 2019] (online) Available from:External Link
Manufacturer/Marketer Address
Lupin Ltd, 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India
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