Lupizep Plus 25 mg/0.5 mg Tablet

Prescription Required
Manufacturer
Storage
Store below 30°C

Introduction

Lupizep Plus 25 mg/0.5 mg Tablet is a prescription medicine used to treat depression. It is a combination medicine which works by increasing the level of chemical messengers in the brain that improves mood. It also calms the brain by decreasing the abnormal and excessive activity of the nerve cells.

Lupizep Plus 25 mg/0.5 mg Tablet can be taken with or without food. It is advised to take it at a fixed time each day to maintain a consistent level of medicine in the blood. Take this medicine in the dose and duration advised by your doctor as it has habit-forming potential. Try to never skip any doses, but if you miss a dose of this medicine, take it as soon as you remember. Finish the full course of treatment even if you feel better. It is important not to stop taking this medicine suddenly as it may result in withdrawal symptoms.

Some common side effects of this medicine include nausea, vomiting, confusion, memory impairment, low sexual desire, confusion, and delayed ejaculation. It may cause dizziness and sleepiness. So, do not drive or do anything that requires mental focus until you know how this medicine affects you.  It is important to inform your doctor if you develop any unusual changes in mood or depression as this medicine may cause suicidal thoughts.

Take caution while taking medicine if you are suffering from liver disease. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Uses of Lupizep Plus Tablet

Benefits of Lupizep Plus Tablet

In Depression

Lupizep Plus 25 mg/0.5 mg Tablet works by affecting the balance of certain chemicals (such as serotonin) in the brain. It helps improve mood and feelings of wellbeing, relieve anxiety and tension, helps you sleep better, and increase your energy level. It is an effective antidepressant but may cause drowsiness. You need to take it regularly as it is prescribed for it to be most effective and should not stop taking it suddenly.

Side effects of Lupizep Plus Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Lupizep Plus

  • Nausea
  • Vomiting
  • Diarrhea
  • Confusion
  • Memory impairment
  • Uncoordinated body movements
  • Drowsiness
  • Tiredness
  • Anorgasmia (decreased orgasm)
  • Low sexual desire
  • Delayed ejaculation

How to use Lupizep Plus Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Lupizep Plus 25 mg/0.5 mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Lupizep Plus Tablet works

Lupizep Plus 25 mg/0.5 mg Tablet is a combination of two medicines: Paroxetine and Clonazepam which has mood-enhancing and anxiety-lowering effects. Paroxetine is selective serotonin reuptake inhibitor (SSRI) which increases the levels of serotonin, a chemical messenger that improves mood. Clonazepam is a benzodiazepine (BZD) which increases the action of GABA, a chemical messenger that suppresses the abnormal activity of the nerve cells in the brain.

Safety advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Lupizep Plus 25 mg/0.5 mg Tablet.
Pregnancy
UNSAFE
Lupizep Plus 25 mg/0.5 mg Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Breast feeding
CONSULT YOUR DOCTOR
Lupizep Plus 25 mg/0.5 mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Lupizep Plus 25 mg/0.5 mg Tablet may cause side effects which could affect your ability to drive.
Kidney
SAFE IF PRESCRIBED
Lupizep Plus 25 mg/0.5 mg Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Lupizep Plus 25 mg/0.5 mg Tablet may not be needed in these patients. Please consult your doctor.
Use of Lupizep Plus 25 mg/0.5 mg Tablet can cause excessive sleepiness in patients with end stage kidney disease.
Liver
CAUTION
Lupizep Plus 25 mg/0.5 mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Lupizep Plus 25 mg/0.5 mg Tablet may be needed. Please consult your doctor.

What if you forget to take Lupizep Plus Tablet?

If you miss a dose of Lupizep Plus 25 mg/0.5 mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Lupizep Plus 25 mg/0.5 mg Tablet
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Parozep 25mg/0.5mg Tablet
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Fordep Forte 25mg/0.5mg Tablet
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₹15.75/tablet
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Quick tips

  • Lupizep Plus 25 mg/0.5 mg Tablet is prescribed for the treatment of depression.
  • It is better to take it with a snack or just after eating breakfast, as this will help to reduce the likelihood of you feeling sick as a side-effect.
  • It can take a week or two after starting this treatment before the effect begins to build up, and 4-6 weeks before you feel the full benefit. Do not stop taking it after a week or two, feeling it is not helping.
  • Avoid taking antacids 2 hours before or after taking Lupizep Plus 25 mg/0.5 mg Tablet as they make it harder for your body to absorb the medicine.
  • Inform your doctor immediately if you get thoughts about harming yourself or ending your life.
  • If you have diabetes, you will be asked to monitor your blood glucose level regularly as this medicine may affect the levels of sugar in your blood.
  • Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress.

Fact Box

Habit Forming
Yes
Therapeutic Class
NEURO CNS

Patient concerns

arrow
DEPRESSION SUFFERING FROM DEPRESSION
Dr. Jyoti Kapoor Madan
Psychiatry
Depression is a persistent state of sadness that is the result of interaction between one's inner biological and psychological state and gets triggered of with environmental stressors. Reactive depression is in response to a situation like loss, sickness, trauma etc. Endogenous depression occurs without any noticeable environmental stressors. Psychological symptoms include lack of interest, negative thinking, irritability, frustration, feeling demotivated etc. Somatic symptoms like fatigue/ weakness/ lack of sleep/ lack of appetite and other physical symptoms are common. Anxiety is common. In severe cases one may feel helpless and hopeless enough to wish for death or attempt suicide. Treatment includes physical and psychiatric work up following which medicines can be prescribed. In milder cases, psychotherapy or counselling is recommended.
Depression,anexity,body. Laziness Depression anxiety,f ear,body laziness
Dr. Ankur Kumar Tanwar
Ayurveda
Ok since how many months you are suffer from
arrow

FAQs

Q. Are there any important warnings associated with the use of Lupizep Plus 25 mg/0.5 mg Tablet?

Lupizep Plus 25 mg/0.5 mg Tablet may increase the suicidal thoughts or actions in some patients, in the first few months of the treatment. Patients having mood or behavioral disorder have a high risk of suicidal thoughts and actions. You should pay close attention and report your doctor of any changes in behavior or mood. Make sure that you visit the doctor for the follow-up appointments as scheduled.

Q. Can I stop taking Lupizep Plus 25 mg/0.5 mg Tablet when my symptoms are relieved?

No, you should continue taking Lupizep Plus 25 mg/0.5 mg Tablet even if you feel well. If you stop Lupizep Plus 25 mg/0.5 mg Tablet suddenly, serious withdrawal symptoms may occur. Your doctor will probably decrease your dose gradually.

Q. How to manage weight gain associated with the use of Lupizep Plus 25 mg/0.5 mg Tablet?

There are reports that suggest that the use of Lupizep Plus 25 mg/0.5 mg Tablet can cause weight gain. If you keep good eating habits and exercise regularly, you might not gain any weight. It is important to remember that it is easier to stop weight gain than losing increased weight.

Q. Can the use of Lupizep Plus 25 mg/0.5 mg Tablet cause sleepiness?

Yes, Lupizep Plus 25 mg/0.5 mg Tablet can make you feel sleepy. Avoid driving, operating machinery, working at heights or participating in potentially dangerous activities till you know how this medicine affects you.

Q. Can the use of Lupizep Plus 25 mg/0.5 mg Tablet affect my sex life?

The use of Lupizep Plus 25 mg/0.5 mg Tablet can affect the sexual life of both men and women. Different sexual problems can occur due to Lupizep Plus 25 mg/0.5 mg Tablet like decreased sexual desire, erectile dysfunction (inability to develop or maintain erection during the sexual activity) and inability to reach orgasm. It can also cause a decrease in satisfaction and cause discomfort during intercourse. If you experience these problems, discuss with your doctor.

Q. Can I drink alcohol while taking Lupizep Plus 25 mg/0.5 mg Tablet?

No, do not drink alcohol while taking Lupizep Plus 25 mg/0.5 mg Tablet. Drinking alcohol can increase the severity of drowsiness or sleepiness caused by Lupizep Plus 25 mg/0.5 mg Tablet.

Q. How long does Lupizep Plus 25 mg/0.5 mg Tablet take to work?

Everybody responds differently to treatment. In general, it can take several weeks to feel the full benefits of Lupizep Plus 25 mg/0.5 mg Tablet, although some people may start to feel better sooner. When taking Lupizep Plus 25 mg/0.5 mg Tablet, it is important to give it time to work.

Q. What are the instructions for the storage and disposal of Lupizep Plus 25 mg/0.5 mg Tablet?

Keep this medicine in the packet or the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

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1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Paroxetine. Miami, Florida:Noven Therapeutics; 2003 [revised 06-2013]. [Accessed 23 Apr. 2019] (online) Available from:External Link
  2. Clonazepam. Boucherville, Québec: Sandoz Canada Inc.; 2018. [Accessed 23 Apr. 2019] (online) Available from:External Link
  3. Paroxetine. South Ruislip, Middlesex: Aurobindo Pharma - Milpharm Ltd.; 2008 [revised 25 Nov. 2018]. [Accessed 23 Apr. 2019] (online) Available from:External Link
  4. Clonazepam. Boucherville, Québec: Sandoz Canada Inc.; 2018. [Accessed 23 Apr. 2019] (online) Available from:External Link

Manufacturer/Marketer address

Lupin Ltd, 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India
Country of origin: India

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We do not facilitate sale of this product at present

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