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Lotebra Eye Drops is a combination medicine used in the treatment of eye infections with inflammation. It kills and stops the growth of bacteria that cause the infection. This way it helps in relieving redness, itching, and swelling caused by the bacteria.

Written By Dr. Lipika Khurana, PGDHHM, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 25 Nov 2025 | 03:07 PM (IST)
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5 ml Ophthalmic Suspension
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General Information

Contains

Loteprednol etabonate (0.5% w/v)+ Tobramycin (0.3% w/v)

Marketer

Entod Pharmaceuticals Ltd

Storage

Store below 25°C
The content is shown in English
Lotebra Eye Drops image
Lotebra Eye Drops image
Lotebra Eye Drops image
Lotebra Eye Drops image
Lotebra Eye Drops image
Lotebra Eye Drops image
Lotebra Eye Drops image

Product introduction

Lotebra Eye Drops is to be used only in the affected eye. Use it in the dose and duration as advised by the doctor. Wash your hands before and after using the medicine. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping the medicine too early may lead to the infection returning or worsening.


The most common side effects include a burning and stinging sensation immediately after instilling, increased intraocular pressure, and redness in the eye. If the symptoms persist for a longer duration, inform your doctor. In case of accidental contact with your ears, nose, or mouth, immediately rinse it off with water.


Inform your doctor if you have a known allergy to any of the ingredients in Lotebra Eye Drops. Let your doctor also know if you are using any other medicine for the same condition. It is advised not to drive or operate heavy machinery immediately after using this medicine, as it may cause blurring of vision.

Uses of Lotebra Ophthalmic Suspension

  • Treatment of Eye infection with inflammation

Benefits of Lotebra Ophthalmic Suspension

Treatment of Eye infection with inflammation
Lotebra Eye Drops stops the growth of bacteria and helps relieve symptoms such as pain, swelling, redness, itching or irritation. It is also used to reduce swelling after an eye surgery. Use it 2-3 times a day for atleast a week or as prescribed by the doctor. Your symptoms might improve after using Lotebra Eye Drops. However, make sure to complete the full course of treatment. This will ensure that the infection is completely cured and prevent it from returning.

Side effects of Lotebra Ophthalmic Suspension

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Lotebra
  • Superficial punctate keratitis
  • Increased intraocular pressure
  • Burning sensation in eye
  • Stinging in the eyes
  • Headache

How to use Lotebra Ophthalmic Suspension

This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Hold the dropper close to the eye without touching it. Gently squeeze the dropper and place the medicine inside the lower eyelid. Wipe off the extra liquid.

How Lotebra Ophthalmic Suspension works

Lotebra Eye Drops is a combination of two medicines: Loteprednol etabonate and Tobramycin. Loteprednol etabonate is a steroid that blocks the production of certain chemical messengers (prostaglandins) that make the eye red, swollen, and itchy. Tobramycin is an antibiotic. It stops bacterial growth in the eye by preventing the synthesis of essential proteins required by bacteria to carry out vital functions.

Quick tips

  • Do not use Lotebra Eye Drops for any condition other than what it was prescribed for, as improper use may lead to resistance or complications.
  • Store Lotebra Eye Drops as directed, usually in a cool, dry place, and keep it out of reach of children.
  • Apply the Lotebra Eye Drops as instructed, ensuring even coverage while avoiding overuse to prevent potential side effects.
  • Lotebra Eye Drops is sterile when packaged. Do not allow the tip of the dropper to touch any surface, as this may contaminate the suspension.

Safety advice

Alcohol

Alcohol

No interaction found/established
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Lotebra Eye Drops during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CAUTION
Lotebra Eye Drops should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.
Driving

Driving

UNSAFE
Lotebra Eye Drops may cause temporary visual disturbances. Do not drive until your vision is clear.
Kidney

Kidney

No interaction found/established
Liver

Liver

No interaction found/established

Frequently asked questions

Wash your hands before use. Tilt your head back, pull down the lower eyelid, and apply the prescribed number of Lotebra Eye Drops. Avoid touching the dropper tip to any surface to prevent contamination. Wait 5-10 minutes before using other eye medications if prescribed.
You should not use Lotebra Eye Drops if you have viral eye infections such as those caused by herpes simplex or chickenpox or if you have fungal eye infections. It is also important to avoid using Lotebra Eye Drops if you are allergic to steroids, tobramycin, or any of the other ingredients in the formulation.
The usual dosing for Lotebra Eye Drops is one to two drops in the affected eye or eyes every four to six hours. However, you should always follow your doctor's specific instructions, as they may recommend more frequent use at the beginning of treatment and a gradual reduction as your symptoms improve.
The serious side effects of Lotebra Eye Drops are high eye pressure (can cause glaucoma), cataracts (cloudy vision), worsening infections (if steroids mask symptoms), and eye pain, vision changes, or severe redness (could signal a serious problem). Reach out to your prescribing doctor immediately if you experience any of these side effects.
The exact time Lotebra Eye Drops takes to show results is not known. However, you may notice improvement in symptoms like redness and discomfort within a few days of Lotebra Eye Drops use. However, full resolution of infection and inflammation may take several weeks. It’s important to continue using the medication for the full prescribed duration, even if your symptoms improve sooner.
Yes, using Lotebra Eye Drops for a prolonged period without medical supervision can increase the risk of serious eye issues like raised intraocular pressure (glaucoma), cataracts, and delayed wound healing. This is why it should only be used for the duration prescribed by your doctor.
While using Lotebra Eye Drops, avoid touching or rubbing your eyes unnecessarily. Do not share your eye drops with anyone else to prevent spreading infections. If you notice new symptoms or your current condition worsens within two days of starting treatment, contact your doctor promptly. Make sure to attend all scheduled follow-up visits to monitor your progress and eye health.
No, you should not wear soft contact lenses while using Lotebra Eye Drops, as it contains a preservative called benzalkonium chloride that can bind to the lenses and cause irritation or damage to the eyes. Wait until your treatment is complete and your doctor confirms it's safe before resuming contact lens use. If necessary, wait at least 15 minutes after using Lotebra Eye Drops before wearing them again.

Fact Box

Habit Forming

No

Therapeutic Class

OPHTHAL

References

  1. CiplaMed. Loteprednol etabonate + Tobramycin [Prescribing Infromation]. [Accessed 01 Feb. 2025] (online) Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Entod Pharmaceuticals Ltd
Address: Ashirwad building, S.V.Road, Opp. Badi Masjid, Bandra(W), Mumbai-400050, INDIA

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Lotebra Eye Drops. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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