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Losartan (50mg)+ Chlorthalidone (12.5mg)
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Losar-CH 12.5 Tablet is a combination of two medicines. It helps to control high blood pressure in different ways. If high blood pressure is not treated it can lead to heart attacks, strokes and kidney failure.
Written By Dr. Swati Mishra, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 25 Aug 2026 | 01:01 AM (IST)
Written By Dr. Swati Mishra, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 25 Aug 2026 | 01:01 AM (IST)
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General Information
Contains
Losartan (50mg)+ Chlorthalidone (12.5mg)
Marketer
Torrent Pharmaceuticals Ltd
Storage
Store below 25°C
The content is shown in English







Product introduction
You can take Losar-CH 12.5 Tablet with or without food. The dose will depend on your condition and how you respond to the medicine. Try to take it at the same time each day. It is important to keep taking this medicine until your doctor tells you not to. It contains a diuretic (water pill) and will make you urinate more so, it is best to avoid taking this medicine within four hours of going to bed. Use this medicine regularly to get the most benefit from it even if you feel well. High blood pressure does not usually have symptoms and if you stop taking it your risk of heart attack or stroke may increase.
The most common side effect is dizziness. Other side effects include feeling tired, nausea, diarrhea, headache, and decreased blood pressure. Frequent urination is not a side effect of this medicine. It is the purpose of chlorthalidone and helps control your blood pressure. You may experience other possible side effects, but most are rare. Make sure you read the leaflet that comes with your medicines and tell your doctor if you are bothered by side effects or they do not go away. It may be possible to adjust your dose or try a different medicine.
This medicine is not recommended during pregnancy and you should ask your doctor before taking it if you have kidney or liver disease, heart trouble or diabetes. Drinking alcohol can further lower your blood pressure and may cause side effects.
The most common side effect is dizziness. Other side effects include feeling tired, nausea, diarrhea, headache, and decreased blood pressure. Frequent urination is not a side effect of this medicine. It is the purpose of chlorthalidone and helps control your blood pressure. You may experience other possible side effects, but most are rare. Make sure you read the leaflet that comes with your medicines and tell your doctor if you are bothered by side effects or they do not go away. It may be possible to adjust your dose or try a different medicine.
This medicine is not recommended during pregnancy and you should ask your doctor before taking it if you have kidney or liver disease, heart trouble or diabetes. Drinking alcohol can further lower your blood pressure and may cause side effects.
Uses of Losar-CH Tablet
Benefits of Losar-CH Tablet
Hypertension (high blood pressure)
Losar-CH 12.5 Tablet is a combination of two medicines namely Losartan and chlorthalidone. It is generally used when one medicine alone is not controlling your blood pressure effectively. Losartan works by relaxing and widening your blood vessels so your blood can flow more easily. This will lower your blood pressure. Chlorthalidone is known as a diuretic (water pill) which increases urine output thereby lowering blood pressure. If your blood pressure is controlled you are less at risk of having a heart attack, stroke, or kidney problems. The medicine must be taken regularly as prescribed to be effective. You do not usually feel any direct benefit from taking this medicine, but it works in the long term to keep you well.
Losar-CH 12.5 Tablet is a combination of two medicines namely Losartan and chlorthalidone. It is generally used when one medicine alone is not controlling your blood pressure effectively. Losartan works by relaxing and widening your blood vessels so your blood can flow more easily. This will lower your blood pressure. Chlorthalidone is known as a diuretic (water pill) which increases urine output thereby lowering blood pressure. If your blood pressure is controlled you are less at risk of having a heart attack, stroke, or kidney problems. The medicine must be taken regularly as prescribed to be effective. You do not usually feel any direct benefit from taking this medicine, but it works in the long term to keep you well.
Side effects of Losar-CH Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Losar-CH
- Limited data available
How to use Losar-CH Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Losar-CH 12.5 Tablet may be taken with or without food.
How Losar-CH Tablet works
Losar-CH 12.5 Tablet is a combination of two medicines:
All substitutes for Losar-CH 12.5 Tablet
For information purposes only. Consult a doctor before taking any medicine.
Quick tips
- You have been prescribed Losar-CH 12.5 Tablet for the treatment of high blood pressure.
- It can be taken with or without food.
- Losar-CH 12.5 Tablet may cause dehydration. Drink plenty of fluids and inform your doctor if you develop extreme thirst, very dry mouth or muscle weakness.
- It may cause dizziness. Get up slowly when rising from a sitting or lying position.
- Use of Losar-CH 12.5 Tablet during pregnancy or breastfeeding is unsafe.
- It may also decrease the risk of stroke and heart attacks.
Safety advice

Alcohol
CAUTION
Alcohol should be used with caution while taking Losar-CH 12.5 Tablet.

Pregnancy
UNSAFE
Losar-CH 12.5 Tablet is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.

Breast feeding
UNSAFE
Losar-CH 12.5 Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving
CONSULT YOUR DOCTOR
It is not known whether Losar-CH 12.5 Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.

Kidney
CAUTION
Losar-CH 12.5 Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Use of Losar-CH 12.5 Tablet is not recommended in these patients.
Use of Losar-CH 12.5 Tablet is not recommended in these patients.

Liver
UNSAFE
Losar-CH 12.5 Tablet is unsafe to use in patients with liver disease and should be avoided.
Use of Losar-CH 12.5 Tablet is not recommended in patients with severe liver disease.
Use of Losar-CH 12.5 Tablet is not recommended in patients with severe liver disease.
Frequently asked questions
Losar-CH 12.5 Tablet is used by many people for lowering blood pressure. This medicine generally has very few side effects. In addition to lowering blood pressure, it also protects kidney function in high blood pressure patients having diabetes and impaired kidney function (diabetic nephropathy). It is also used to treat chronic heart failure when treatment with other medicines fails to prove effective. It also decreases the risk of stroke in patients who are hypertensive and have thicker left ventricle (heart chamber).
Take Losar-CH 12.5 Tablet exactly as per your doctor’s advice. Losar-CH 12.5 Tablet tablets are meant for oral intake. Swallow the tablet with water; do not crush or chew. You can take it with or without food. The dose will depend on the condition you are being treated for. It is recommended that you take your first dose before bedtime, as it can make you dizzy. After taking the first dose, you can take it at any time of the day but try to take it at the same time each day.
The blood pressure lowering effect of Losar-CH 12.5 Tablet can be seen after about 6 hours of taking it. The effect of the medicine lasts for 24 hours. You may take about 3-6 weeks to see the full benefits of this medicine
Yes, the use of Losar-CH 12.5 Tablet can make you feel dizzy. This may occur when you suddenly get up from a lying or sitting position. To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
Lifestyle changes play a major role in keeping you healthy if you are taking Losar-CH 12.5 Tablet. Avoid taking excess salt in your diet and find ways to reduce or manage stress in your life. Practice yoga or meditation or take up a hobby. Ensure that you have a sound sleep every night as this also helps to reduce stress levels and helps to keep your blood pressure normal. Stop smoking and alcohol consumption as this helps in lowering your blood pressure and preventing heart problems. Exercise regularly and take a balanced diet that includes whole grains, fresh fruits, vegetables and fat-free products. Consult your doctor if you need any further guidance to get the maximum benefit of Losar-CH 12.5 Tablet and to keep yourself healthy.
Losar-CH 12.5 Tablet may impair kidney function in patients having severe heart failure, chronic kidney disease or narrow or blocked blood vessels that lead to kidney damage (renal artery stenosis). Its use may affect the kidney function in patients who have experienced severe fluid loss or dehydration due to vomiting, diarrhea or excessive use of diuretics. Therefore, Losar-CH 12.5 Tablet should be used cautiously in these patients and their kidney function should be regularly monitored.
No, Losar-CH 12.5 Tablet does not cause weight gain. However, if your kidney function deteriorates then your body may swell due to accumulation of water, causing weight gain. Call your doctor if you experience unexplained weight gain or swelling in your feet, ankles or hands.
Taking Losar-CH 12.5 Tablet during the last 6 months of pregnancy can cause serious harm or even death of the unborn baby. Tell your doctor if you are pregnant or plan to become pregnant. Do not take Losar-CH 12.5 Tablet if you are pregnant. If you become pregnant while taking Losar-CH 12.5 Tablet, stop taking Losar-CH 12.5 Tablet and call your doctor immediately.
You may have to take Losar-CH 12.5 Tablet for a long term, even life long. Losar-CH 12.5 Tablet controls blood pressure but does not cure it. Talk to your doctor in case you have any concerns regarding Losar-CH 12.5 Tablet, but do not stop taking it without consulting the doctor.
Long-term use of Losar-CH 12.5 Tablet is generally considered to be safe. However, in some cases, long-term use of Losar-CH 12.5 Tablet may adversely affect the functioning of the kidneys. Therefore, the doctor may prescribe regular blood tests to keep a track of how well the kidneys are working.
Fact Box
Habit Forming
No
Therapeutic Class
CARDIAC
Related lab tests
References
- Losartan potassium. Hoddesdon, Hertfordshire: Merck Sharp & Dohme Limited; 2009 [revised 22 Mar. 2018]. [Accessed 11 Apr. 2019] (online) Available from:
- Drugs.com. Losartan Pregnancy and Breastfeeding Warnings. [Accessed 11 Apr. 2019] (online) Available from:
- Drugs.com. Chlortalidone. [Accessed 11 Apr. 2019] (online) Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
Marketer details
Name: Torrent Pharmaceuticals Ltd
Address: Off. Ashram Road, Ahmedabad - 380 009., Gujarat, India
Address: Off. Ashram Road, Ahmedabad - 380 009., Gujarat, India
Vendor Details
Country of origin: India
Lab tests offered by us
- CBC (Complete Blood Count)
- FBS (Fasting Blood Sugar)
- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- PPBS (Postprandial Blood Sugar)
- Lipid Profile
- Vitamin D (25-Hydroxy)
- Urine R/M (Urine Routine & Microscopy)
- Coronavirus Covid -19 test- RT PCR
- LFT (Liver Function Test)
- KFT (Kidney Function Test)
- TSH (Thyroid Stimulating Hormone) Ultrasensitive
- ESR (Erythrocyte Sedimentation Rate)
- Uric Acid, Serum
- Vitamin B12
- CRP (C-Reactive Protein), Quantitative
- Urine C/S (Urine Culture and Sensitivity)
- Serum Electrolytes
- Serum Calcium
- Serum Creatinine
- Diabetes Screening (HbA1C & Fasting Sugar)
- KFT with Electrolytes (Kidney Function Test with Electrolytes)
- Cholesterol - Total
- Hb (Hemoglobin)
- Complete Hemogram (CBC & ESR)
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