Leofenac-MR Tablet

Aceclofenac (100mg)+ Paracetamol (500mg)+ Tizanidine (2mg)

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Leofenac-MR Tablet is a combination of three medicines used in the treatment of muscular pain. It works by blocking the release of certain chemical messengers in the brain that cause pain and inflammation (redness and swelling). It also relaxes the muscles and provides relief from stiffness or spasm.

Written By Dr. Anuj Saini, MMST, MBBS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 25 Nov 2025 | 03:07 PM (IST)

₹42 MRP ₹46.4110% off

Gurgaon

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General Information

Contains

Aceclofenac (100mg)+ Paracetamol (500mg)+ Tizanidine (2mg)

Marketer

Emar HealthCare

Storage

Store below 30°C

The content is shown in English

Product introduction

Leofenac-MR Tablet should be taken with food. This will prevent you from getting an upset stomach. The dose will depend on what you are taking it for and how well it helps your symptoms. You should take it as advised by your doctor. Do not take more or use it for a longer duration than recommended by the doctor.

The most common side effects of this medicine include vomiting, nausea, heartburn, stomach pain, diarrhea, loss of appetite, and weakness. If any of these side effects bother you or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the side effects.

Before taking it, you should let your doctor know if you have a history of ulcer or bleeding in your stomach, high blood pressure, or have any trouble with your heart, kidneys, or liver. Let your doctor also know about all the other medicines you are taking because they may affect, or be affected by, this medicine.

Pregnant or breastfeeding women should consult their doctor before starting treatment. You should also avoid drinking alcohol while you are taking this medicine, as alcohol can cause excessive drowsiness.

Uses of Leofenac-MR Tablet

Treatment of Muscular pain

Benefits of Leofenac-MR Tablet

Treatment of Muscular pain
Leofenac-MR Tablet treats muscle pain by relaxing stiff muscles. It also reduces swelling in the muscles. Altogether, it helps in easy movement and reduces discomfort. Once you see some improvement, you can start doing therapy exercises (such as walking or breathing exercises) that will help you get your strength back more quickly. It is advisable to continue taking Leofenac-MR Tablet until your doctor advises you to stop.

Side effects of Leofenac-MR Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Leofenac-MR

Vomiting
Nausea
Heartburn
Stomach pain
Diarrhea
Loss of appetite
Weakness
Sleepiness
Dryness in mouth

How to use Leofenac-MR Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Leofenac-MR Tablet should be taken with or after food.

How Leofenac-MR Tablet works

Leofenac-MR Tablet is a combination of three medicines: Paracetamol, Aceclofenac, and Tizanidine. Paracetamol is an antipyretic (fever reducer) and Aceclofenac is a non-steroidal antiinflammatory drug (NSAID). They work by blocking the release of certain chemical messengers in the brain that cause fever and pain respectively. Tizanidine is a muscle relaxant. It works on the centers in the brain and spinal cord to relieve muscle stiffness or spasm and to improve pain and movement of muscles.

All substitutes for Leofenac-MR Tablet

For information purposes only. Consult a doctor before taking any medicine.

Leemoflam-MR 100mg/500mg/2mg Tablet

by LeeMed Pharmaceuticals

₹5.68/tablet

35% costlier

Kinectine MR 100mg/500mg/2mg Tablet

by Anglo-French Drugs & Industries Ltd

₹4.74/tablet

13% costlier

Quick tips

This medicine is most effective when taken along with proper rest and physical therapy.
Avoid consuming alcohol when taking Leofenac-MR Tablet as it may cause excessive drowsiness and increase the risk of liver damage.
Older adults may have increased drowsiness, confusion, and higher risk of falling as a result of taking Leofenac-MR Tablet.
Do not take it with any other medicine containing acetaminophen (drugs for pain/fever or cough-and-cold) without asking your doctor first.

Safety advice

Alcohol

UNSAFE

Do not drink alcohol while you are taking this medicine. Leofenac-MR Tablet may cause excessive drowsiness when taken with alcohol.

Pregnancy

CONSULT YOUR DOCTOR

Information regarding the use of Leofenac-MR Tablet during pregnancy is not available. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Leofenac-MR Tablet during breastfeeding is not available. Please consult your doctor.

Driving

CONSULT YOUR DOCTOR

It is not known whether Leofenac-MR Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.

Kidney

CONSULT YOUR DOCTOR

There is limited data available on the use of Leofenac-MR Tablet in patients with kidney disease. Please consult your doctor.

Liver

CONSULT YOUR DOCTOR

There is limited data available on the use of Leofenac-MR Tablet in patients with liver disease.

Frequently asked questions

What is Leofenac-MR Tablet used for?

Leofenac-MR Tablet is used for quick and effective relief of pain, muscle spasm, and inflammation caused by conditions such as lower back pain, neck pain, sprains, strains, injury-related pain, joint pain, post-surgical pain, or even severe headaches.

Who should not use Leofenac-MR Tablet?

Individuals should not use Leofenac-MR Tablet if they have severe heart failure, uncontrolled high blood pressure, serious liver or kidney disease, ongoing gastrointestinal bleeding or ulcers, a history of asthma or allergic reactions to painkillers (NSAIDs), or if they are allergic to any ingredient in this medicine.

Does Leofenac-MR Tablet cause drowsiness?

Leofenac-MR Tablet may make you feel sleepy, dizzy, or lightheaded. Do not drive or operate heavy machinery until you know how the medicine affects you. Get enough rest, and avoid important activities requiring alertness if you are feeling drowsy.

Can I use Leofenac-MR Tablet for a long time?

Long-term or repeated use of Leofenac-MR Tablet should be done only under a doctor’s supervision, as it may affect your liver or kidneys. Chronic use may also increase the risk of stomach ulcers or bleeding. Regular monitoring and check-ups are important if you need ongoing pain relief.

What are the serious side effects of Leofenac-MR Tablet?

The serious side effects of Leofenac-MR Tablet include black or bloody stools, severe stomach pain, vomiting blood, jaundice (yellowing of the skin or eyes), persistent drowsiness, swelling, rash, trouble breathing, or confusion. Contact your doctor immediately. These may be signs of severe side effects requiring urgent attention.

Fact Box

Habit Forming

Therapeutic Class

PAIN ANALGESICS

Related lab tests

Creatinine Kinase

References

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Emar HealthCare
Address: b-112 2nd floor, patpat gung, jp extension, patparganj-mayur vihar phase 1, delhi - 110091

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Leofenac-MR Tablet

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Leofenac-MR Tablet

Benefits of Leofenac-MR Tablet

Side effects of Leofenac-MR Tablet

How to use Leofenac-MR Tablet

How Leofenac-MR Tablet works

All substitutes for Leofenac-MR Tablet

Leemoflam-MR 100mg/500mg/2mg Tablet

Kinectine MR 100mg/500mg/2mg Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

What is Leofenac-MR Tablet used for?

Who should not use Leofenac-MR Tablet?

Does Leofenac-MR Tablet cause drowsiness?

Can I use Leofenac-MR Tablet for a long time?

What are the serious side effects of Leofenac-MR Tablet?

Fact Box

Habit Forming

Therapeutic Class

Related lab tests

Creatinine Kinase

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

Related/Popular tests