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Lemtrada 12mg Infusion

Prescription Required
SALT COMPOSITION

Product introduction

Lemtrada 12mg Infusion is used in the treatment of blood cancer (chronic lymphocytic leukemia) and multiple sclerosis (MS). It marks the cancer cells for destruction by the body's immune system. It also modulates the immune system to limit its attacks on the nervous system.

Lemtrada 12mg Infusion is given under the supervision of a doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Rash, headache, and insomnia are some common side effects of this medicine. This medicine may reduce the number of blood cells (white blood cells) in your blood, thereby, increasing the susceptibility to infections or bleeding. Thus, inform your doctor immediately if you develop fever, chills, cough, mouth sores, or trouble breathing, and unusual bruising or bleeding, or blood in the urine. You will be checked regularly after giving the medication as it may cause fatal reactions such as chest pain, breathlessness, slow or irregular heartbeat.

Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Benefits of Lemtrada Infusion

In Blood cancer (Chronic lymphocytic leukemia)

Blood cancer, also called leukemia, is a cancer of the blood-forming tissues, that decreases the body's ability to fight infection. Lemtrada 12mg Infusion kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is an effective medicine but you should discuss the side effects and benefits of this medicine with your doctor. Let your doctor know if any of the side effects bothers you.

In Multiple sclerosis (MS)

Multiple sclerosis (MS) is a disease of the brain and spinal cord in which a person’s own immune system attacks the protective sheath (called myelin) of the nerves. This leads to symptoms such as vision loss, pain, fatigue and improper coordination. Lemtrada 12mg Infusion helps to suppress the body’s immune system, thereby reducing the progression of the disease. It reduces the inflammation of the damaged nerves, prevents further damage and stabilises your immune system. It improves muscle strength and helps the patients to walk better. This makes the patients more confident and enhances their quality of life.

Side effects of Lemtrada Infusion

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Lemtrada

  • Rash
  • Headache
  • Insomnia (difficulty in sleeping)
  • Nausea
  • Upper respiratory tract infection
  • Decreased white blood cell count
  • Fatigue
  • Fever
  • Itching
  • Flushing (sense of warmth in the face, ears, neck and trunk)
  • Hives
  • Decreased white blood cell count (lymphocytes)

How to use Lemtrada Infusion

Your doctor or nurse will give you this medicine. Kindly do not self-administer.

How Lemtrada Infusion works

Lemtrada 12mg Infusion is a monoclonal antibody. It flags the cancer cells for destruction by the body's immune system. It also modulates the immune system to limit its attacks on the nervous system.

Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Lemtrada 12mg Infusion. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Lemtrada 12mg Infusion may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Lemtrada 12mg Infusion is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Lemtrada 12mg Infusion may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CONSULT YOUR DOCTOR
There is limited information available on the use of Lemtrada 12mg Infusion in patients with kidney disease. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Lemtrada 12mg Infusion in patients with liver disease. Please consult your doctor.

What if you forget to take Lemtrada Infusion?

If you miss a dose of Lemtrada 12mg Infusion, please consult your doctor.\n

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine

Quick tips

  • Lemtrada 12mg Infusion is given as an injection into the veins under the supervision of a doctor.

Fact Box

Chemical Class
Monoclonal antibody (mAb)
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
CD52 Inhibitors

Patient concerns

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FAQs

Q. How will you know that Lemtrada 12mg Infusion is working?

Keep taking this medicine exactly as directed until your doctor tells you to stop. Regular scans will reveal whether your tumor is responding to the treatment. Your doctor will determine when those scans should be scheduled.

Q. What precautions should I take to reduce the chances of getting infected during treatment with Lemtrada 12mg Infusion?

Since Lemtrada 12mg Infusion lowers the number of white blood cells and platelets in your blood, it puts you at a risk of getting an infection or bleeding. In order to prevent, avoid people who have infections. Check with your doctor immediately if you think you may be getting an infection, or if you get a fever, chills, cough; be careful not to cut yourself when you are using sharp objects such as a razor or nail cutters; and use a toothbrush with soft bristles to prevent bleeding from gums.

Q. How to get relief from feelings of nausea during the treatment?

Eat smaller, more frequent meals to reduce the feeling of nausea. Avoid food that is salty, spicy, fried, or fatty. Sucking on lozenges and chewing gums may also help.Your doctor might prescribe you some anti-nausea medications to get immediate relief.

Q. I have noticed some changes in my skin, and hair after taking Lemtrada 12mg Infusion. What should I do?

Use a moisturizer to get relief from rashes, dry and itchy skin. While taking this medicine, the hair on your head may become brittle. You may also experience patchy hair loss or thinning. This tends to resolve once treatment is stopped.

Q. Are there any precaution for tingling sensation and numbness in my arms and legs?

This medicine causes tingling, numbness, pain, or burning sensation in your arms or legs. Be careful when moving around, as the numbness may make it harder to walk, feel your hands or feet, or increase your risk of falls. Talk to your doctor if you feel these symptoms. You may need to change your dose or schedule.

Q. What are some of the tests conducted before and during the treatment with Lemtrada 12mg Infusion?

Your doctor will prescribe blood tests to check your levels of blood cells and how well your liver and kidneys are working.

Q. Can Lemtrada 12mg Infusion be taken during pregnancy?

This treatment may harm a baby developing in the womb. It is important not to become pregnant or father a child while you are having treatment and for at least 6 months afterward. Talk to your doctor about effective contraception before starting the treatment.

Q. Is Lemtrada 12mg Infusion safe during breastfeeding?

Do not breastfeed while taking this medicine and for 4 months after the last dose. This is because Lemtrada 12mg Infusion might pass into breast milk and could therefore harm your baby.

Q. Can I take vaccination while on treatment with Lemtrada 12mg Infusion?

It is advisable not to receive any kind of immunization with live vaccine while taking this medicine and for up to 12 months afterward. The length of time depends on the treatment you are having. Ask your doctor how long you should avoid live vaccinations.

Q. When should I call my doctor right away?

Get medical help right away if you have swelling in your mouth or throat, trouble breathing, severe weakness, fast, slow, or irregular heartbeat, chest pain, and severe rash.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Krensky AM, Bennett WM, Vincenti F. Immunosuppressants, Tolerogens, and Immunostimulants. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1018.
  2. Lake DF, Briggs AD, Akporiaye ET. Immunopharmacology. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 977.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 35.
  4. Alemtuzumab. Oxford, Oxfordshire: Genzyme Therapeutics; 2013 [revised 22 Nov. 2018]. [Accessed 26 Mar. 2019] (online) Available from:External Link
  5. Alemtuzumab. Kendall Street Cambridge, MA: Genzyme Corporation; 2001. [Accessed 26 Mar. 2019] (online) Available from:External Link
  6. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Alemtuzumab. [Updated 2019 Feb 28]. [Accessed 18 Feb. 2020] (online) Available from:External Link

Marketer details

Name: Sanofi India Ltd
Address: Sanofi House, CTS No.117-B, L&T Business Park, Saki Vihar Road, Powai, Mumbai 400072
Country of origin: India
Expires on or after: August, 2024

A licensed vendor partner from your nearest location will deliver Lemtrada 12mg Infusion. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

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