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Koftrodex Syrup is a combination medicine used in the treatment of cough with mucus. It thins mucus in the nose, windpipe and lungs making it easier to cough out. It also relieves allergic symptoms like runny nose, watery eyes and sneezing and also relieves minor throat irritation.

Written By Dr. Lipika Khurana, PGDHHM, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 27 Nov 2025 | 02:48 PM (IST)
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General Information

Contains

Ambroxol (30mg)+ Desloratadine (2.5mg)+ Guaifenesin (50mg)+ Menthol (1mg)

Marketer

Leeford Healthcare Ltd

Storage

Store below 30°C
The content is shown in English
Koftrodex Syrup image
Koftrodex Syrup image

Product introduction

Koftrodex Syrup is taken with or without food in a dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your doctor know about all other medications you are taking as some may affect, or be affected by this medicine.

The most common side effects are nausea, dryness in mouth, diarrhea, stomach discomfort, vomiting, fatigue, headache, and rash. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects. This medicine can also cause sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can make sleepiness worse.

Never support self-medication or recommend your medicine to another person. It is beneficial to have plenty of fluids while taking this medication. Before taking this medicine, you should tell your doctor if you are pregnant, planning pregnancy or breastfeeding.

Uses of Koftrodex Syrup

Benefits of Koftrodex Syrup

Cough with mucus
Koftrodex Syrup gives relief from cough with mucus. It helps to loosen thick mucus, making it easier to cough out. This makes breathing easy and reduces the frequency of coughing. Koftrodex Syrup also relieves allergy symptoms like itchy or watery eyes, sneezing and runny nose. Apart from this, it produces a sensation of coolness and relieves minor throat irritation. Koftrodex Syrup usually starts to work within a few minutes and the effects can last up to several hours. Along with medications, drink enough luke warm water and gargle with warm salt water to ease the symptoms.

Side effects of Koftrodex Syrup

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Koftrodex
  • Nausea
  • Dryness in mouth
  • Diarrhea
  • Stomach discomfort
  • Vomiting
  • Allergic reaction
  • Fatigue
  • Headache
  • Dizziness
  • Rash
  • Hives

How to use Koftrodex Syrup

Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Koftrodex Syrup may be taken with or without food.

How Koftrodex Syrup works

Koftrodex Syrup is a combination of four medicines: Ambroxol, Desloratadine, Guaifenesin and Menthol which relieve cough with mucus.

All substitutes for Koftrodex Syrup

For information purposes only. Consult a doctor before taking any medicine.

Koftrodex Syrup

by Leeford Healthcare Ltd
₹65/syrup
30% cheaper
<h3 class=bodySemiBold>Koftrodex Syrup</h3>

Quick tips

  • Koftrodex Syrup is prescribed to get relief from cough with mucus.
  • Drink warm water to help loosen the congestion and lubricate your throat while you are taking this medication.
  • Take exactly as directed by your doctor or on the label. Do not increase the dosage or take for longer than is recommended. Use a proper measuring cup or spoon to measure the dosage.
  • If you are drowsy after taking Koftrodex Syrup, you should not drive or operate any machinery.
  • In general, most coughs do not last more than 2 weeks. If your cough does last longer than this then it's better to see your doctor.
  • Inform your doctor if you have a history of stomach ulcers or asthma.
  • Inform your doctor if you are taking any other medications, e.g., anti-depressants.
  • Koftrodex Syrup should not be given to kids.

Safety advice

Alcohol

Alcohol

UNSAFE
Do not drink alcohol while you are taking this medicine. Koftrodex Syrup may cause excessive drowsiness when taken with alcohol.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Koftrodex Syrup during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Information regarding the use of Koftrodex Syrup during breastfeeding is not available. Please consult your doctor.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Koftrodex Syrup alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Kidney

Kidney

SAFE IF PRESCRIBED
Koftrodex Syrup is probably safe to use in patients with kidney disease. Limited data suggest dose adjustment may not be needed.
Liver

Liver

SAFE IF PRESCRIBED
Koftrodex Syrup is probably safe to use in patients with liver disease. Limited data suggest dose adjustment may not be needed.

Fact Box

Habit Forming

No

Therapeutic Class

RESPIRATORY

Related lab tests

Complete Blood Count

References

  1. Desloratadine. Whitehouse Station, New Jersey: Merck & Co., Inc.; 2001 [revised Apr. 2014]. [Accessed 26 Apr. 2019] (online) Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Leeford Healthcare Ltd
Address: 203, Mangalam, Keshav Road, Sion, Mumbai-400 022, India

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Koftrodex Syrup. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's â„ž and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

Lab tests offered by us

Why we need a prescription?
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Prescriptions are complex documents. We proof read and recheck at various steps to provide you the right medication in the correct form and dose
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Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945
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