Overview
Uses and benefits
Side effects
How to use
How drug works
Safety advice
Missed dose
All substitutes
Quick tips
Fact box
Patient concerns
FAQs

Author Details

Written By

Dr. Anuj Saini

MMST, MBBS

Reviewed By

Dr. Mekhala Chandra

MD, MBBS

Last updated

19 Nov 2025 | 09:36 PM (IST)

We provide you with authentic, trustworthy and relevant information

Want to know more

Have issue with the content?

Report Problem

Kocitaf 50mg/200mg/25mg Tablet

Prescription Required

Marketer

Mylan Pharmaceuticals Pvt Ltd

SALT COMPOSITION

Dolutegravir (50mg) + Emtricitabine (200mg) + Tenofovir Alafenamide (25mg)

Storage

Store below 30°C

View available alternative with same salt composition

Click here to view all substitutes

Product introduction

Kocitaf 50mg/200mg/25mg Tablet is a combination of antiretrovirals medicines. It is prescribed to treat HIV (human immunodeficiency virus) infection. It boosts up the immunity to fight against HIV to manage or treat AIDS (acquired immunodeficiency syndrome).

Kocitaf 50mg/200mg/25mg Tablet restricts the growth of HIV in the body and reduces the risk of getting HIV-related complications to improve the lifespan of an individual. The medicine can be taken with or without food. Taking these medicines regularly at the same time increases their effectiveness. A dose of this medicine should not be missed as it can affect your recovery. It is important to complete the full course of the treatment until your doctor advises you to stop it. Sudden discontinuation of the treatment may affect the potency of the medicine.

The most common side effects of this medicine are insomnia, fatigue, headache, nausea, adn diarrhea. These side effects are generally temporary, but if they persist or become serious inform your doctor. This medicine can also make you feel lazy or weak, so it is advised to avoid driving. Drinking plenty of fluid can help you to cope up with the side effects, so stay hydrated.

Before starting with the treatment, you should consult your doctor if you are pregnant or breastfeeding, or have any health condition. Your doctor may suggest regular blood tests to check your blood counts, kidney and liver functions, and other health conditions. If you are HIV positive, you should not breastfeed or share personal belongings like razors or toothbrushes. Consult your doctor to know about safe sex methods in order to prevent transmission of HIV during intercourse.

Uses of Kocitaf Tablet

HIV infection

Benefits of Kocitaf Tablet

In HIV infection

Kocitaf 50mg/200mg/25mg Tablet prevents HIV from multiplying in the body. It helps control the infection and make the immune system work better. This lowers the chances of getting complications, such as new infections, and improves the quality of life. This medicine is always taken in combination with other antiretroviral medicines.

It is not a cure of HIV or AIDS and should not be used to prevent HIV after accidental exposure to a risk. It is important to take this medicine as prescribed by the doctor. Taking all doses in the right amount at the right times greatly increases the effectiveness of this combination of medicines and reduces the chances of HIV infection becoming resistant to antiretroviral medicines. Although taking this medicine does not prevent the passing of HIV to other people.

Side effects of Kocitaf Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Kocitaf

Insomnia (difficulty in sleeping)
Diarrhea
Headache
Nausea
Fatigue

How to use Kocitaf Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Kocitaf 50mg/200mg/25mg Tablet may be taken with or without food.

How Kocitaf Tablet works

Kocitaf 50mg/200mg/25mg Tablet is a combination of three medicines: Dolutegravir, Emtricitabine and Tenofovir Alafenamide. It is an anti-HIV medication and works by preventing the action of reverse transcriptase enzyme. This enzyme is responsible for production of HIV.

Safety advice

Alcohol

CAUTION

Alcohol should be used with caution while taking Kocitaf 50mg/200mg/25mg Tablet.

Pregnancy

SAFE IF PRESCRIBED

$med_name is generally considered safe to use during pregnancy. Animal studies do not indicate harmful effects. However, there are limited human studies.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Kocitaf 50mg/200mg/25mg Tablet during breastfeeding is not available. Please consult your doctor.

Driving

CONSULT YOUR DOCTOR

It is not known whether Kocitaf 50mg/200mg/25mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.

Kidney

UNSAFE

Kocitaf 50mg/200mg/25mg Tablet is unsafe to use in patients with kidney disease and should be avoided.

Liver

UNSAFE

Kocitaf 50mg/200mg/25mg Tablet is unsafe to use in patients with liver disease and should be avoided.

What if you forget to take Kocitaf Tablet?

If you miss a dose of Kocitaf 50mg/200mg/25mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Kocitaf 50mg/200mg/25mg Tablet

₹123.6/Tablet

Spegra Tablet

Emcure Pharmaceuticals Ltd

₹134.27/tablet

9% costlier

Quick tips

Kocitaf 50mg/200mg/25mg Tablet is given to slow the progress of HIV infection.
Although treatment with Kocitaf 50mg/200mg/25mg Tablet can reduce the risk of you passing HIV to others through sexual contact, it does not stop it. It is therefore important to use condoms.
If you develop any infection soon after taking Kocitaf 50mg/200mg/25mg Tablet, inform your doctor. As a result of taking Kocitaf 50mg/200mg/25mg Tablet, your immune system may start fighting an infection that was present before you started the treatment, but you might not be aware of.
It may cause weakening of your bones. Exercise regularly and take calcium and vitamin D supplements as suggested by your doctor.
It is common for people with HIV to feel low or even depressed, especially soon after the diagnosis has been made. If you have any feelings of depression it is advisable to speak with your doctor.

Fact Box

Habit Forming

Therapeutic Class

ANTI INFECTIVES

Patient concerns

i have unprotected sex with my friend. Can I take any drugs now to prevent any STD/HIV infection

Dr. Shyam Gupta

Obstetrics and Gynaecology

Hello PATIENT to 1mg. There is some medicine for prophylactic but you need to see physician for prescription and better you check HIV status of both partner

hello, one of my frnd suffering with hiv infection from last 2yrs her cd4 is more than 470 and viral load is zero undetectable now she is using art medicines i have doubt that can we have to use art medicine in the whole life or can we stop it once we get viral load zero

Dr. Atula Gupta

Dermatology

You still need to be on ART even if the viral load is undetectable

What is Kocitaf 50mg/200mg/25mg Tablet used for?

Kocitaf 50mg/200mg/25mg Tablet is used to treat HIV-1 infection as a complete regimen to help keep the virus under control and protect your immune system. It may be started in people with no known resistance to these medicines, as advised by your doctor.

Who should not take Kocitaf 50mg/200mg/25mg Tablet?

An individual should not take Kocitaf 50mg/200mg/25mg Tablet if they have ever had a severe allergic reaction to dolutegravir, emtricitabine, or tenofovir alafenamide, or any ingredient of the medicine. Also, Kocitaf 50mg/200mg/25mg Tablet should be avoided if taking dofetilide (a heart rhythm medicine), because of dangerous interactions with dolutegravir.

Why do I need hepatitis B (HBV) testing before starting Kocitaf 50mg/200mg/25mg Tablet?

Emtricitabine and tenofovir alafenamide present in Kocitaf 50mg/200mg/25mg Tablet also act against hepatitis B. If you have HBV and later stop this medicine suddenly, your hepatitis B can flare up and become serious. That’s why doctors test for HBV first and monitor closely if treatment stops.

What are the serious side effects of Kocitaf 50mg/200mg/25mg Tablet?

Serious side effects of Kocitaf 50mg/200mg/25mg Tablet include severe allergic reaction (rash with fever, mouth sores, swelling, trouble breathing), severe liver problems (yellow skin/eyes, dark urine, stomach pain, extreme tiredness), and lactic acidosis symptoms (deep/fast breathing, severe fatigue, nausea, belly pain). Get medical care immediately if these occur.

Can Kocitaf 50mg/200mg/25mg Tablet affect my kidneys or bones?

$ame may affect kidneys and bones. Your doctor may check kidney function and bone health if you are at risk. Tell your doctor if you have a history of kidney disease, bone problems, or if you take other kidney-impacting medicines.

Can stopping Kocitaf 50mg/200mg/25mg Tablet suddenly if I am feeling good be risky?

Yes. If you also have hepatitis B, stopping Kocitaf 50mg/200mg/25mg Tablet can cause a serious flare of hepatitis. Even without HBV, stopping HIV medicines can let the virus rebound and risk resistance. Always talk to your doctor before stopping or changing doses.

Will Kocitaf 50mg/200mg/25mg Tablet affect my mood or sleep?

Some people taking Kocitaf 50mg/200mg/25mg Tablet report sleep problems, anxiety, or low mood. Tell your doctor if you notice worsening sleep, depression, or unusual thoughts. Your doctor may review your treatment plan.

Does Kocitaf 50mg/200mg/25mg Tablet raise the chances of infections?

Getting HIV under control by Kocitaf 50mg/200mg/25mg Tablet lowers infection risk overall. However, when your immune system starts to recover, it can cause an inflammatory “immune reconstitution” response to old, hidden infections. Report new or worsening symptoms (fever, cough, eye changes, swollen glands) promptly.

Show less

Related lab tests

HIV 1 & 2, Ab Western Blot

HIV 1 And 2 Antibody - Chromatography

HIV 1 And 2 Antibody - ELISA

Want to share the information?

Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Flexner CW. Antiretroviral Agents and Treatment of HIV Infection. In: Brunton LL, Hilal-Dandan R, Knollmann BC (Editors). Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 13th ed. New York, NY: McGraw-Hill Education; 2018. pp. 1138-1157.
Safrin S. Antiviral Agents. In: Katzung BG, Masters SB, Trevor AJ (Editors). Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 861-890.
Dolutegravir, emtricitabine and tenofovir alafenamide [FDA Label]. Hyderabad, India: Mylan Laboratories Limited; 2018. [Accessed 16 Apr. 2021] (online) Available from:
Dolutegravir, emtricitabine and tenofovir alafenamide [Prescribing Information]. Anakapalli, India: Laurus Labs Limited; 2023. [Accessed 22 Aug. 2024] (online) Available from: