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Isocaldin 300 mg/10 mg Tablet


Overview

Introduction

Isocaldin 300 mg/10 mg Tablet is a combination medicine used in the treatment of tuberculosis. It prevents the growth of the microorganisms that cause the infection. It also protects the nerves from the side effects that may occur during the course of the treatment.

Isocaldin 300 mg/10 mg Tablet is a prescription medicine and it is to be taken it as suggested by the doctor. It should be taken in an empty stomach and take it at a fixed time to ensure better efficacy. Do not consume more than the recommended dose, as this may have harmful effects on your body. If you miss a dose, take it as soon as you remember. The course of the treatment must be completed even if you feel better. Sudden discontinuation of the treatment may affect the potency of the medicine. The medicine may take some to show its effects on the symptoms. However, it is advised to consult the doctor if you feel an aggravation of the condition or if your condition does not improve.

Some common side effects of this medicine are nausea, vomiting, fever, dark-colored urine, sweating, increased saliva, etc. To cope up with the side effects, you should drink plenty of water. If any of the side effects get aggravated, you must consult your doctor immediately. Generally, serious side effects are rare. If you experience any allergic reaction (rashes, itching, swelling, shortness of breath, etc.), you must seek immediate medical help.

Before taking this medicine, you should tell your doctor if you are taking any medicines for any health condition. Patients with liver and kidney ailments must take this medicine with proper consultation and caution. Pregnant or breastfeeding women should also consult with the doctor before taking it. Avoid drinking alcohol as it can cause excessive drowsiness with this medicine. It usually does not impair your ability to drive, but you should not drive if it makes you feel sleepy or dizzy. During the treatment, you must take adequate rest and eat a healthy diet for a faster recovery. While on the medication, your doctor may ask for a few laboratory and diagnostic tests to know the effects of the medicine on your body.

Uses of Isocaldin Tablet

Side effects of Isocaldin Tablet

Common
  • Rash
  • Fever
  • Peripheral neuropathy (tingling and numbness of feet and hand)
  • Increased liver enzymes
  • Jaundice

How to use Isocaldin Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Isocaldin 300 mg/10 mg Tablet is to be taken empty stomach.
Avoid Isocaldin 300 mg/10 mg Tablet with tyramine-rich food such as cheese, smoked fish, meats and some types of beer.

How Isocaldin Tablet works

Isocaldin 300 mg/10 mg Tablet is a combination of two medicines: Isoniazid and vitamin B6 (pyridoxine). Isoniazid is an antibiotic which prevents the TB bacteria from forming their own protective covering. This kills the bacteria and eradicates the infection. Vitamin B6 (pyridoxine) is added to prevent nerve damage which may be a side effect of isoniazid.

Safety Advice

Alcohol
UNSAFE
Consuming alcohol while taking Isocaldin 300 mg/10 mg Tablet may cause symptoms such as flushing, increased heart beat, nausea, thirst, chest pain and low blood pressure (Disulfiram reaction).
Pregnancy
CONSULT YOUR DOCTOR
Isocaldin 300 mg/10 mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breastfeeding
SAFE IF PRESCRIBED
Isocaldin 300 mg/10 mg Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Driving
UNSAFE
Isocaldin 300 mg/10 mg Tablet may cause side effects which could affect your ability to drive.
Isocaldin 300 mg/10 mg Tablet can cause fits, mental health problems and optic neuritis (inflammation of the optic nerve that may cause loss of vision.) This may affect your driving ability.
Kidney
SAFE IF PRESCRIBED
Isocaldin 300 mg/10 mg Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Isocaldin 300 mg/10 mg Tablet may not be needed in these patients. Please consult your doctor.
Liver
SAFE IF PRESCRIBED
Isocaldin 300 mg/10 mg Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Isocaldin 300 mg/10 mg Tablet may not be needed in these patients. Please consult your doctor.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Isocaldin 300 mg/10 mg Tablet
₹2.77/Tablet
₹3.32/Tablet
20% costlier
Inatos 300mg/10mg Tablet
TOSC International Pvt Ltd
₹0.31/Tablet
save 89%

Patient Concerns

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Sgot 42.8, sgpt 47.10. Taking recin 300, combutol 800, cifrocin 5 mg
Dr. Sunil Sekhri
Diabetology
Since you are taking medication of tuberculosis increase in Liver enzymes does happen. If you develop jaundice then change of medications might be required
I have cough problem from 25 days. I used penther syrup, tuspel cough syrup and tuff DMR , DMR 20 tablet, Roxud 150 mg but no much recovery so prescribe me for that.
Dr. Pushkar Mani
Physician
refer to chest specialist and do test for tuberculosis
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Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Gumbo T. Chemotherapy of Tuberculosis, Mycobacterium Avium Complex Disease, and Leprosy. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman's: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: The McGraw-Hill Companies, Inc.; 2011. [Accessed 09 Apr. 2019] (online) Available from:External Link
  2. ScienceDirect. Pyridoxine. [Accessed 09 Apr. 2019] (online) Available from:External Link
  3. Isoniazid. Nottingham, Nottinghamshire: Boots Contract Manufacturing; 2015. [Accessed 09 Apr. 2019] (online) Available from:External Link
  4. MedlinePlus. Pyridoxine. [Accessed 09 Apr. 2019] (online) Available from:External Link
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