Insuman Comb 25 Injection is a combination of two medicines, an intermediate-acting and a short-acting type of insulin. It is used in the treatment of diabetes mellitus (type 1 and 2) to improve blood sugar control both in adults and children. It helps maintain the blood sugar levels in diabetic patients.
Insuman Comb 25 Injection is normally prescribed along with other diabetes medicines. Your doctor or nurse will teach you the correct way of injecting it under the skin. It should be taken 15 minutes before a meal or within 20 minutes after starting a meal. Don’t stop taking it unless your doctor tells you to.
It is only part of a treatment program that should also include a healthy diet, regular exercise, and weight reduction as advised by your doctor. Check your blood sugar levels regularly, keep track of your results and share them with your doctor. This is very important to work out the correct dose of the medicine for you.
The most common side effect of this medicine is low blood sugar levels (hypoglycemia). To prevent this, it's important to always inject the correct dose of medicine only, have regular meals, and monitor your blood sugar levels regularly. Drinking excessive alcohol can also lead to a fall in your blood sugar levels. Other side effects include reactions at the injection site like redness or swelling. Some people gain weight while taking insulin. You may also notice a rash, edema (swelling), or itching while taking this medicine.
Do not use this medicine when you have low blood glucose levels (hypoglycemia). Tell your doctor if you’ve ever had kidney, liver or heart problems before starting treatment. Pregnant or breastfeeding women should also consult their doctor as the dose may need to be changed.
Insuman Comb 25 Injection contains an intermediate-acting and a short-acting type of insulin. Together, they ensure rapid and consistent sugar control that helps control blood sugar levels for an entire day. It is given as an injection and your doctor or nurse will train you on the correct way to inject it. Managing blood glucose levels is an essential part of managing diabetes. If you can control the level you will reduce the risk of getting any of the serious complications of diabetes such as kidney damage, eye damage, nerve problems, and loss of limbs. Taking this medicine regularly along with proper diet and exercise will help you live a normal, healthy life.
Side effects of Insuman Comb Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Insuman Comb
Hypoglycemia (low blood glucose level)
Injection site reactions (pain, swelling, redness)
Weight gain
How to use Insuman Comb Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Insuman Comb Injection works
Insulin Isophane has a prolonged duration of action, while human insulin has a fast onset of action. Together, they ensure rapid and consistent sugar control by facilitating reuptake of sugar in muscle and fat cells and suppressing the production of sugar in the liver.
Safety advice
Alcohol
UNSAFE
It is unsafe to consume alcohol with Insuman Comb 25 Injection.
Pregnancy
SAFE IF PRESCRIBED
Insuman Comb 25 Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Breast feeding
SAFE IF PRESCRIBED
Insuman Comb 25 Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
CAUTION
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
Kidney
CAUTION
Insuman Comb 25 Injection should be used with caution in patients with kidney disease. Dose adjustment of Insuman Comb 25 Injection may be needed. Please consult your doctor. Regular monitoring of blood glucose levels is recommended for dose adjustment.
Liver
CAUTION
Insuman Comb 25 Injection should be used with caution in patients with liver disease. Dose adjustment of Insuman Comb 25 Injection may be needed. Please consult your doctor.
What if you forget to take Insuman Comb Injection?
If you have missed a dose of Insuman Comb 25 Injection, your blood sugar level may become too high (hyperglycemia). Check your blood sugar and then take the next dose accordingly.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine
Quick tips
Take it 15 minutes before a meal or within 20 minutes after starting a meal.
Injection below the skin of the abdomen results in faster absorption than other injection sites such as skin of the upper arms, thighs, or buttocks. After injection, the site of injection should not be massaged.
Injection sites must be rotated to prevent hard lumps from developing at one site.
Change to another type or brand of insulin should be done under strict medical supervision as it may require a change in dosage.
Hypoglycemia (low blood sugar level) may occur when taken along with other antidiabetic medicines, alcohol or on delaying/skipping a meal. Carry a sugar source with you for immediate relief.
Do not share your insulin device with other people, even if the needle has been changed. You may give other people a serious infection or get a serious infection from them.
Opened vials/cartridges stay good at room temperature for up to 4 weeks, while unopened vials must be placed in the refrigerator (2°C–8°C).
Fact Box
Habit Forming
No
Therapeutic Class
ANTI DIABETIC
Patient concerns
equivalent to Insuman 25/75 40UI medicine. Please suggest
Sugar level above 200 after meal medicine taking glycomet gp2 BD and insulin insuman comb 25 (20 units) BD Also 3 months sugar level is 9.2
Dr. Sanjay Bhatt
Physician
Confirm about your diet failure. You needs some dose adjustment in the medicine you are taking if you are not having any diet failure. So discuss with your doctor and try to keep sugar level in normal limits.
A person can control his or her sugar levels by doing regular exercise and walk or regular aerobic exercises at least 30 to 45 minutes per day.MEDICAL NUTRITIONAL THERAPY THAT IS TO MAINTAIN CALORIES INTAKE AS PER BMI .TAKE HELP OF DIABETIC EDUCATOR. VISIT YOUR DOCTOR AND FOLLOW ALL WHAT DOCTOR SUGGESTED.IN TIME ALL ROUTINE INVESTIGATIONS SHOULD BE DONE.you should not treat it as disease but a start of a healthy life.Uncontrolled sugar levels for long time leads to lower limb weakness which is neuropathy and which is followed by foot ulcers and other complications like kidney or heart problems .online prescription is not allowed without seeing pt.so contact doctor nearby for any change or dose adjustment or visit my clinic at gurgaon sector 52 RdCity snergy multi speciality clinic near SRS MARKET
Diabetes is a medical condition in which sugar, or glucose, levels build up in your bloodstream. There?s not enough insulin to move the sugar into your cells, which are where the sugar is used for energy. This causes your body to rely on alternative energy sources in your tissues, muscles, and organs. This is a chain reaction that can cause a variety of symptoms. Type 2 diabetes can develop slowly. The symptoms may be mild and easy to dismiss at first. The early symptoms may include: constant hunger a lack of energy fatigue weight loss excessive thirst frequent urination dry mouth itchy skin blurry visionDiet is an important tool to keep your heart healthy and blood sugar levels within a safe and healthy range. It doesn?t have to be complicated or unpleasant. The diet recommended for people with type 2 diabetes is the same diet just about everyone should follow. It boils down to a few key actions: Eat meals and snacks on schedule. Choose a variety of foods that are high in nutrition and low in empty calories. Be careful not to overeat. Read food labels closely.
A person can control his or her sugar levels by regular exercise and walk or regular aerobic exercises at least 30 to 45 minutes per day.MEDICAL NUTRITIONAL THERAPY THAT IS TO MAINTAIN CALORIES INTAKE AS PER BMI .TAKE HELP OF DIABETIC EDUCATOR. VISIT YOU DOCTOR AND LOW ALL WHAT DOCTOR SUGGESTED.IN TIME ALL ROUTINE INVESTIGATIONS SHOULD BE DONE.you souls not treat it as disease but start of a healthy life.Uncontrolled sugar levels for long time leads to lower limb weakness which is neuropathy and which is followed by foot ulcers and other complications.online prescription is not allowed without seeing pt.so contact doctor nearby for any change or dose adjustment or visit my clinic at gurgaon sector 52 RdCity snergy multi speciality clinic near SRS MARKET
It is not good control. A person can control his or her sugar levels by doing regular exercise and walk or regular aerobic exercises at least 30 to 45 minutes per day.MEDICAL NUTRITIONAL THERAPY THAT IS TO MAINTAIN CALORIES INTAKE AS PER BMI .TAKE HELP OF DIABETIC EDUCATOR. VISIT YOUR DOCTOR AND FOLLOW ALL WHAT DOCTOR SUGGESTED.IN TIME ALL ROUTINE INVESTIGATIONS SHOULD BE DONE.you should not treat it as disease but a start of a healthy life.Uncontrolled sugar levels for long time leads to lower limb weakness which is neuropathy and which is followed by foot ulcers and other complications like kidney or heart problems .online prescription is not allowed without seeing pt.so contact doctor nearby for any change or dose adjustment or visit my clinic at gurgaon sector 52 RdCity snergy multi speciality clinic near SRS MARKET
*Type 2 diabetes mellitus, Type 1 diabetes mellitus
How much was the improvement?
Excellent
43%
Average
40%
Poor
17%
What were the side-effects while using Insuman Comb 25 Injection?
No Side Effec*
50%
Hypoglycemia *
18%
Itching
9%
Lipodystrophy*
9%
Injection sit*
9%
*No Side Effect, Hypoglycemia (low blood glucose level), Lipodystrophy (skin thickening or pits at the injection site), Injection site allergic reaction
How do you take Insuman Comb Injection?
Empty stomach
44%
With or witho*
28%
With food
28%
*With or without food
Please rate Insuman Comb 25 Injection on price
Expensive
44%
Average
39%
Not Expensive
17%
FAQs
Can I drink alcohol while taking Insuman Comb 25 Injection?
No, it is not safe to drink alcohol while using Insuman Comb 25 Injection. Drinking alcohol while using this medicine may lower your blood sugar levels and cause unexpected hypoglycemia.
What are the instructions for storage and disposal of Insuman Comb 25 Injection?
Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
Which is the best area to inject Insuman Comb 25 Injection?
Insuman Comb 25 Injection is to be injected under the skin (subcutaneously). The best areas to give Insuman Comb 25 Injection are your stomach, upper thigh, upper arm or buttocks.
What are the symptoms of high blood sugar?
Symptoms of high blood sugar include frequent urination, increased thirst, fatigue, nausea, vomiting, shortness of breath, stomach pain, fruity breath odor, dry mouth and a fast heartbeat.
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References
European Medicine Agency. Insulin Isophane/NPH+Human Insulin/Soluble Insulin; 2002 [revised Nov. 2013]. [Accessed 08 Apr. 2019] (online) Available from:
Isophane. Basingstoke, Hampshire: Eli Lilly and Company Limited; 2014 [revised 30 Jul. 2018]. [Accessed 08 Apr. 2019] (online) Available from:
Human Insulin. Gatwick, West Sussex: Novo Nordisk Limited; 2002 [revised Mar. 2018]. [Accessed 08 Apr. 2019] (online) Available from:
Mixtard [Summary of Product Characteristics]. Bagsværd, Denmark; Novo Nordisk A/S; 2021. [Accessed 13 Oct. 2021] (online) Available from:
Humulin [FDA Prescribing Information]. Indianapolis, USA; Lilly USA, LLC.; 2018. [Accessed 13 Oct. 2021] (online) Available from:
Medscape. Insulin Isophane/NPH/ Human Insulin/Soluble Insulin. [Accessed 08 Apr. 2019] (online) Available from:
Human insulin isophane suspension and human insulin injection [Prescribing Information]. Indianapolis, IN: Lilly USA, LLC; 2018. [Accessed 14 Aug. 2024] (online) Available from:
Marketer details
Name: Sanofi India Ltd
Address: Sanofi House, CTS No.117-B, L&T Business Park, Saki Vihar Road, Powai, Mumbai 400072