







Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 25 Nov 2025 | 03:07 PM (IST)
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General Information








Product introduction
Insulate-NP Tablet can be taken with or without food, preferably at bedtime. It is advised to take medicine at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration advised by your doctor. If you miss a dose of this medicine, take it as soon as you remember. Finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to the doctor.
Some common side effects of this medicine are nausea, edema, weight gain and dryness in the mouth. It may also cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. It is important to inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts.
Before taking the medicine you should tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Inform your doctor if you are taking any other medicines, as some medicines (including antacids and alcohol) do affect the way it works and can increase the chances of side effects.
Uses of Insulate-NP Tablet
Benefits of Insulate-NP Tablet
Insulate-NP Tablet is a combination of medicines used to treat long-lasting (chronic) pain caused by nerve damage due to diabetes, shingles or spinal cord injury. It reduces pain and its associated symptoms such as mood changes, sleep problems, and tiredness. Pregabalin, an active ingredient of this medicine, is thought to work by interfering with pain signals that travel through the damaged nerves and the brain. It also contains nutritional supplements that improve nerve conduction.
Side effects of Insulate-NP Tablet
- Dryness in mouth
- Weight gain
- Edema (swelling)
- Impaired concentration
- Blurred vision
- Nausea
- Increased saliva production
- Sleepiness
- Dizziness
How to use Insulate-NP Tablet
How Insulate-NP Tablet works
Quick tips
- Insulate-NP Tablet is used to treat certain types of long-lasting pain caused by damage to nerves.
- Dry mouth may occur as a side effect. Frequent mouth rinses, good oral hygiene, increased water intake and sugarless candy may help.
- Along with taking Insulate-NP Tablet, your doctor might advise you to undergo physiotherapy to get relief from pain.
- Inform your doctor if you are taking any other pain-relieving medicines.
Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver
Fact Box
Habit Forming
Therapeutic Class
References
- Gupta JK, Sana QS. Potential Benefits of Methylcobalamin: A Review. Austin J Pharmacol Ther. 2015; 3(3).1076. [Accessed 30 Mar. 2020] (online) Available from:
- Jayabalan B, Low LL. Vitamin B supplementation for diabetic peripheral neuropathy. Singapore Med J. 2016;57(2):55-59. [Accessed 30 Mar. 2020] (online) Available from:
- Zhang M, Han W, Hu S, et al. Methylcobalamin: A potential vitamin of pain killer. Neural Plast. 2013;2013:424651. [Accessed 30 Mar. 2020] (online) Available from:
- Stahl SM, editor. Pregabalin. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 557-60.




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