INSTREL GEL is a combination of three medicines: Tramadol, Paracetamol / Acetaminophen and Serratiopeptidase which relieve severe pain. Tramadol is an opoid which works by blocking transmission of pain signals to the brain to lower pain perception. Paracetamol / Acetaminophen is an analgesic (pain reliever) which blocks the release of certain chemical messengers that cause fever and pain. Serratiopeptidase is an enzyme which works by breaking down abnormal proteins at the site of inflammation.
INSTREL GEL may be unsafe to use during pregnancy. Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
No information is available on the use of INSTREL GEL during lactation. Please consult your doctor.
Do not drive unless you are feeling well. INSTREL GEL may cause side effects such as drowsiness and blurred vision. If this happens, do not drive.
INSTREL GEL should be used with caution in patients with kidney disease. Dose adjustment of INSTREL GEL may be needed. Please consult your doctor.
INSTREL GEL should be used with caution in patients with liver disease. Dose adjustment of INSTREL GEL may be needed. Please consult your doctor. However, the use of INSTREL GEL is not recommended in patients with severe liver disease and active liver disease.