Overview
Uses and benefits
Side effects
How to use
How drug works
Safety advice
Missed dose
All substitutes
Quick tips
Fact box
Patient concerns
FAQs

Author Details

Written By

Dr. Subita Alagh

BDS

Reviewed By

Dr. Rajeev Sharma

MBA, MBBS

Last updated

03 Dec 2025 | 11:06 PM (IST)

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Home>I Nem>i nem 250mg/250mg injection

I Nem 250mg/250mg Injection

Prescription Required

Marketer

Glenmark Pharmaceuticals Ltd

SALT COMPOSITION

Imipenem (250mg) + Cilastatin (250mg)

Storage

Store below 30°C

View available alternative with same salt composition

Product introduction

I Nem 250mg/250mg Injection is a combination of antibiotic medicines. It is prescribed to treat various types of severe bacterial infections. It fights against the infection-causing microorganisms to prevent further infections.

I Nem 250mg/250mg Injection should only be administered under the supervision of a healthcare professional. Do not miss any scheduled appointments for taking this medicine. The course of the medicine should be completed even if you feel better.

The common side effects of this medicine are nausea, vomiting, diarrhea, rashes, etc. You may also experience injection site redness, swelling, and pain that goes away with time. If any of the side effects get aggravated, you must consult your doctor immediately. If you experience any allergic reaction (rashes, itching, swelling, shortness of breath, etc.), you must seek immediate medical help.

Before taking this medicine, you should tell your doctor if you are taking any medicines for any health condition. Pregnant or breastfeeding women should also consult with their doctor before taking it. Avoid drinking alcohol as it can cause excessive drowsiness with this medicine. It usually does not impair your ability to drive, but you should not drive if it makes you feel sleepy or dizzy.

Uses of I Nem Injection

Severe bacterial infections

Benefits of I Nem Injection

In Severe bacterial infections

I Nem 250mg/250mg Injection works by killing bacteria which can cause serious infections. It is used to treat many different types of bacterial infections. It is given by a doctor or nurse into a vein and should not be self-administered. I Nem 250mg/250mg Injection usually makes you feel better very quickly but you should continue taking it as prescribed even when you feel better to make sure that all bacteria are killed and do not become resistant.

Side effects of I Nem Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of I Nem

Nausea
Vomiting
Diarrhea
Rash

How to use I Nem Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How I Nem Injection works

I Nem 250mg/250mg Injection is a combination of two medicines: Imipenem and Cilastatin. Imipenem is an antibiotic. It works by preventing the formation of the bacterial protective covering which is essential for the survival of bacteria in the human body. Cilastatin is dehydropeptidase I inhibitor which blocks the activity of an enzyme (dehydropeptidase I) that causes breakdown of Imipenem. Hence, it helps Imipenem stay active in your body for a longer period of time.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with I Nem 250mg/250mg Injection. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

The safety of I Nem 250mg/250mg Injection during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

SAFE IF PRESCRIBED

I Nem 250mg/250mg Injection may be safe to use during breastfeeding. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Driving

UNSAFE

I Nem 250mg/250mg Injection may cause side effects that could affect your ability to drive.
There are some side effects associated with this medicine (such as seeing, hearing, or feeling something that is not there) that may affect some patients' ability to drive.

Kidney

CAUTION

I Nem 250mg/250mg Injection should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver

CONSULT YOUR DOCTOR

There is limited data available on the use of I Nem 250mg/250mg Injection in patients with liver disease.

What if you forget to take I Nem Injection?

If you miss a dose of I Nem 250mg/250mg Injection, please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

No substitutes found for this medicine

Quick tips

I Nem 250mg/250mg Injection is used to treat severe bacterial infections, including those acquired in hospital and those involving many different types of bacteria.
It is given by a drip into a vein (intravenous infusion) over 20 to 60 minutes.
Tell you doctor if you are allergic to penicillin as this medicine should be avoided or used with caution in penicillin allergy.
Your doctor may monitor your liver and kidney function while you are having treatment with this medication.
Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it doesn't stop or if you find blood in your stools.
Inform your doctor if you are pregnant, planning to conceive, or breastfeeding.

Fact Box

Habit Forming

Therapeutic Class

ANTI INFECTIVES

Patient concerns

I got my body tests done and found testosterone below the minimum range. Please advice.

Dr. Vinod Raina

Sexology

Take inj sustonone 250mg depot once a month

Hi, Please tell what to do to get ridoff from the fungal infection which is in the upper inner part of thigh and is very itchy,rough,reddish. I have tried two courses of medicine in last 3 months buts its coming back. Medicine which I tried was fluka 150 and livotiz 10 mg. And Allegra 180 plus Tyza 250mg. Candid b was the cream and Mycrodum was the powder. Please help amd suggest the best

Dr. Souvik Sardar

Dermatology

Hello PATIENT all the creamsTab sebifin 250mg - 1tab once daily after lunch for 4wksAlong with that apply ebernet cream - apply twice daily for 4wks

Hi there ! I've been married for a year and half now and had not had any intimate relationship with my wife. I had read about ED and consulted well known Sexologist in Chennai (Dr. karthik Gunasekaran)who suggested a circumcisuon as I could not retract my foreskin due to phimosis. He had also given few meds ( Anti Oxidants capsule s, Horney goat weed capsules, and Xtraman cream. It's been 3 and half months after circumcision now. Most of it looks healed but at the left side rim of the penis there is small inflammation. It doesn't hurt but I'm jus worried about it. I have started the medication just a week back. But did not notice any change. I'm still unable to have an intercourse because of soft erections. Is there any solution to this. I work in the IT sector where work involves stress, most of the time poor diet options. I also smoke which I'm trying to get rid off ( any help how to quit ? ). Before the circumcision when I had all the test done. The said my testrone levels were way low ( almost of an 65 yr old man. Ranging from a scale of 1 to 7 mine was 1). Any solution to this ? Thanks in advance !

Dr. Vinod Raina

Sexology

Take tab dasutra 30 mg 1od at night for thirty days with tab critizyme bd for thirty daysTake inj testosterone 250mg once a monthThen revert back to me

I am suffering from from the last four days taking ciplox 500 and sumo tablet. Fever only comes in the morning when I wake up . I am attaching reports also

Dr. Sarthak Chakravarty

Physician

As per your reports everything is almost fine. Most likely chances are you may have UTI. I would suggest to continue Ciprofloxacin 500 for total 5 days then 250mg (half tablet) 5 days more. Take Paracetamol 500 whenever you get fever. Also take cap. Vizilac 1 cap daily

For how long is I Nem 250mg/250mg Injection used?

Duration of treatment with I Nem 250mg/250mg Injection depends on the severity of your infection, which will be decided by your doctor.

How long does I Nem 250mg/250mg Injection take to work?

Usually, I Nem 250mg/250mg Injection starts working soon after taking it. However, it may take some days to kill all the harmful bacteria and make you feel better.

Related lab tests

Complete Blood Count

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Imipenem and Cilastatin [Prescribing Information]. Cadempino, Switzerland: Zambon Switzerland Ltd.; 2024. [Accessed 03 Dec. 2025]. Available from:
Salmon-Rousseau A, Martins C, Blot M, et al. Comparative review of imipenem/cilastatin versus meropenem. Med Mal Infect. 2020;50(4):316-322. [Accessed 03 Dec. 2025]. Available from:
LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012–. Imipenem-Cilastatin. 2017 Jan 17. [Accessed 03 Dec. 2025]. Available from: