Product introduction
HEPtral 400mg Tablet is a medicine used in the treatment of intrahepatic cholestasis and other chronic liver diseases. It works by restoring the natural compound in the liver that helps protect liver cells from damage, improves the flow of bile, and supports overall healthy liver function.
HEPtral 400mg Tablet is usually recommended to be taken before meals, as this improves absorption. The exact dose depends on your body weight and the condition being treated. To get the most benefit, it is important to take this medicine regularly and at the same time each day. Treatment may need to continue for several months or longer, depending on your doctor’s advice. Even if your symptoms improve, do not stop taking it unless your doctor tells you to.
The most common side effects of HEPtral 400mg Tablet are nausea, abdominal discomfort, and diarrhea. These effects are usually mild and temporary. If diarrhea becomes bothersome, your doctor may adjust your dose or stop the treatment. Drinking plenty of fluids can help prevent dehydration if you experience diarrhea or constipation. Rarely, some people may also experience a headache, trouble sleeping, or a skin rash. If any side effect worries you, consult with a doctor.
HEPtral 400mg Tablet should be used with caution in patients with a history of bipolar disorder, as this medicine may rarely trigger mood swings. Use during pregnancy and breastfeeding should only be under medical advice. This medicine can interact with other drugs, so let your doctor know about all the medicines and supplements you are taking. Avoid drinking alcohol while on treatment, as this may increase the strain on your liver and worsen side effects.
Uses of HEPtral Tablet
- Treatment of Liver disease
Benefits of HEPtral Tablet
In Treatment of Liver disease
HEPtral 400mg Tablet is used in the management of liver disease, including conditions such as intrahepatic cholestasis and chronic liver disorders. It supports the liver’s natural detoxification processes, helps restore antioxidant levels like glutathione, and improves bile flow. It protects liver cells and promotes their healthy function, playing an important role in maintaining overall liver health.
Side effects of HEPtral Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of HEPtral
- Nausea
- Diarrhea
- Abdominal pain
How to use HEPtral Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. HEPtral 400mg Tablet is to be taken empty stomach.
How HEPtral Tablet works
HEPtral 400mg Tablet works by helping the liver make and restore important substances that protect its cells. It increases the liver’s natural antioxidants, reduces damage from toxins, and improves the flow of bile. This supports healthier liver function in conditions like intrahepatic cholestasis and chronic liver disease.
Safety advice
Alcohol
CAUTION
Caution is advised when consuming alcohol with HEPtral 400mg Tablet. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Information regarding the use of HEPtral 400mg Tablet during pregnancy is not available. Please consult your doctor.
High doses used in late pregnancy have not shown harmful effects. However, in the first trimester, use only if clearly needed, and always under medical supervision.
High doses used in late pregnancy have not shown harmful effects. However, in the first trimester, use only if clearly needed, and always under medical supervision.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of HEPtral 400mg Tablet during breastfeeding is not available. Please consult your doctor.
Use during breastfeeding only if the expected benefit to the mother outweighs the possible risk to the baby.
Use during breastfeeding only if the expected benefit to the mother outweighs the possible risk to the baby.
Driving
UNSAFE
HEPtral 400mg Tablet may cause side effects which could affect your ability to drive.
This medicine may cause dizziness. Do not drive or operate machinery until you know how it affects you.
This medicine may cause dizziness. Do not drive or operate machinery until you know how it affects you.
Kidney
CAUTION
HEPtral 400mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of HEPtral 400mg Tablet may be needed. Please consult your doctor.
Liver
SAFE IF PRESCRIBED
HEPtral 400mg Tablet is safe to use in patients with liver disease. No dose adjustment of HEPtral 400mg Tablet is recommended.
What if you forget to take HEPtral Tablet?
If you miss a dose of HEPtral 400mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
HEPtral 400mg Tablet
₹140.0/Tablet
Cirrosam 400 Tablet
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₹112.53/tablet
20% cheaper
Hepadem 400 Tablet
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₹29.9/tablet
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New Nusam 400 Tablet
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₹91.5/tablet
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Efekart 400mg Tablet
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Adefresh 400 Tablet
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₹71/tablet
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Quick tips
- Diarrhea may occur as a side effect. Drink plenty of fluids and inform your doctor if diarrhea persists or if you find blood in your stools.
- To make sure it is safe for you, consult with your doctor if you are pregnant, planning pregnancy, or breastfeeding before starting this medicine.
- Follow a healthy diet, avoid alcohol, and keep yourself well hydrated to complement the treatment.
- Inform your doctor if you have bipolar disorder or a history of mood swings; this medicine may trigger mania/hypomania.
- Tell your doctor if you have rare genetic problems affecting methionine metabolism (e.g., homocystinuria).
- Your doctor may check vitamin B12 and folate levels during treatment.
Fact Box
Chemical Class
Amino acid derivative
Habit Forming
No
Therapeutic Class
GASTRO INTESTINAL
Action Class
Hepatoprotective Agents
Patient concerns
User feedback
Patients taking HEPtral 400mg Tablet
Once A Day
60%
Twice A Day
40%
What are you using HEPtral Tablet for?
Others
77%
Nutritional d*
23%
*Nutritional deficiencies
How much was the improvement?
Excellent
40%
Average
39%
Poor
21%
What were the side-effects while using HEPtral 400mg Tablet?
No Side Effec*
76%
Dizziness
6%
Insomnia (dif*
6%
Vomiting
2%
Constipation
2%
*No Side Effect, Insomnia (difficulty in sleeping)
How do you take HEPtral Tablet?
Empty stomach
64%
With or witho*
32%
With food
5%
*With or without food
Please rate HEPtral 400mg Tablet on price
Expensive
65%
Average
19%
Not Expensive
16%
FAQs
What is HEPtral 400mg Tablet used for?
HEPtral 400mg Tablet is mainly used for the treatment of intrahepatic cholestasis, a condition in which the flow of bile from the liver is reduced, and in certain liver diseases. It helps improve bile secretion and protect liver cells from damage. This helps relieve symptoms such as itching, tiredness, and digestive discomfort that often occur in these conditions.
How does HEPtral 400mg Tablet work in liver disease?
HEPtral 400mg Tablet is a natural substance produced in the body that plays an important role in liver health. In people with liver disease, its levels are usually lower than normal. Taking HEPtral 400mg Tablet helps restore these levels, which improves bile flow, protects liver cells from harmful toxins and oxidative stress, and supports the liver’s natural detoxification functions. This way it helps the liver work more effectively and reduce the complications associated with cholestasis and other liver problems.
How should HEPtral 400mg Tablet be taken?
Take HEPtral 400mg Tablet exactly as prescribed by your doctor. The dose and duration of treatment depend on your medical condition, response to treatment, and your doctor’s judgment. Stopping or changing the dose on your own is not advised, as it may affect the effectiveness of treatment.
Is HEPtral 400mg Tablet safe during pregnancy or breastfeeding?
HEPtral 400mg Tablet should only be used during pregnancy or breastfeeding if it is clearly recommended by your doctor. The safety of this medicine in these conditions has not been fully established, so medical supervision is essential. Always consult your doctor before taking this medicine if you are pregnant, planning to become pregnant, or breastfeeding.
Can I take HEPtral 400mg Tablet with other medicines?
You should inform your doctor about all other medicines, supplements, or herbal products that you are currently taking. This will help your doctor decide if HEPtral 400mg Tablet is safe to use alongside them and will reduce the risk of any possible interactions that could affect your treatment or overall health.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 04 Sept. 2025] (online) Available from:
- Ademetionine [Product Label]. Ahmedabad, Gujarat: La Renon Healthcare Private Limited; 2022. [Accessed 04 Sept. 2025] (online) Available from:
- MIMS Malaysia: Ademetionine [Full Prescribing Information]. [Accessed 04 Sept. 2025] (online) Available from:
- Ademetionine [Product Information]. Turkey: World Medicine İlaç San. ve Tic. А.Ş. [Accessed 04 Sept. 2025] (online) Available from:
- Zeelab Pharmacy: Ademetionine [Product Information]. [Accessed 04 Sept. 2025] (online) Available from:
Marketer details
Name: Abbott
Address: 16th Floor, Godrej BKC, Plot – C, “G” Block, Bandra-Kurla Complex, Bandra (East), Mumbai – 400 051, India
Country of origin: India
Expires on or after: April, 2026
A licensed vendor partner from your nearest location will deliver HEPtral 400mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
Expires on or after: April, 2026
A licensed vendor partner from your nearest location will deliver HEPtral 400mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
In case of any issues, contact us
Email ID: [email protected]Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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MRP₹1457 4% OFF
₹1400
Inclusive of all taxes
10.0 tablets in 1 strip
New GST benefit included in this MRP, may differ from label
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