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Hepamac Tablet

L-Ornithine L-Aspartate (250mg)+ Silymarin (140mg)

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Hepamac Tablet is a prescription medicine which has a combination of medicines that are used in the treatment of liver disease. It works by protecting the liver from harmful chemical substances.

Written By Dr. Subita Alagh, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 17 Apr 2026 | 12:51 PM (IST)

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General Information

Contains

L-Ornithine L-Aspartate (250mg)+ Silymarin (140mg)

Marketer

Unimac Pharmaceuticals Pvt Ltd

Storage

Store below 25°C

The content is shown in English

Product introduction

Hepamac Tablet may be taken with or without food. It should be used in the dose and duration as prescribed by your doctor. It is advised to take this medicine at a fixed time. This medicine should not be taken more than the recommended dose.

Common side effects of this medicine include nausea, bloating, headache, and abdominal pain. If you experience any side effect persistent or bother you, let your doctor know. They may be able to suggest ways to reduce or prevent the symptoms.

Remember to finish the full course of treatment even if you feel better. It is important that this medicine should not be stopped suddenly without consulting your doctor.

Uses of Hepamac Tablet

Liver disease

Benefits of Hepamac Tablet

Liver disease
Hepamac Tablet is a combination medicine that protects the liver from damage against harmful chemicals known as free radicals, thereby improving overall health of the liver. This helps the liver to perform its normal functions. It can help prevent or delay liver damage in most people, especially if you start taking it in the early stages. To make the medicine more effective and for general health benefits, stop smoking, maintain a healthy weight, and do not drink too much alcohol.

Side effects of Hepamac Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Hepamac

Tiredness
Diarrhea
Abdominal pain
Flatulence
Bloating
Itching

How to use Hepamac Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Hepamac Tablet may be taken with or without food.

How Hepamac Tablet works

Hepamac Tablet is a combination of two medicines. L-Ornithine L-Aspartate is a combination of two amino acids which works by protecting the liver from harmful chemical substances (free radicals), thus preventing liver damage. Silymarin is an active principle obtained from milk thistle seed (Silybum marianum). It might protect liver cells from toxic chemicals and drugs. It also seems to have antioxidant and anti-inflammatory effects.

All substitutes for Hepamac Tablet

For information purposes only. Consult a doctor before taking any medicine.

Triohep 250mg/140mg Tablet

by Amazone Pharmaceuticals Pvt Ltd

₹18.2/tablet

31% cheaper

Quick tips

Hepamac Tablet protects the liver cells from toxins and helps the liver to perform its normal functions.
Your doctor may monitor your liver function and bilirubin levels every month for the next 3 months after the start of therapy, and every 6 months thereafter.
You will be regularly monitored for blood creatinine and blood/urine urea levels while on treatment with Hepamac Tablet.
Avoid smoking and drinking as it further degrades liver functioning.
Avoid fatty food, take a healthy diet, and exercise regularly.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Hepamac Tablet

Pregnancy

CONSULT YOUR DOCTOR

The safety of Hepamac Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Hepamac Tablet during breastfeeding is not available. Please consult your doctor.

Driving

UNSAFE

Hepamac Tablet may cause side effects that could affect your ability to drive.

Kidney

CAUTION

Hepamac Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.

Liver

CAUTION

Hepamac Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.

Frequently asked questions

What is Hepamac Tablet used for?

Hepamac Tablet is primarily used to support liver health, treat liver disorders like fatty liver disease, hepatitis, and liver cirrhosis, and help reduce elevated ammonia levels in the body that can affect brain function.

Can Hepamac Tablet help with symptoms of brain fog or confusion related to liver problems?

Is Hepamac Tablet suitable for people with fatty liver disease?

Yes, Hepamac Tablet is frequently prescribed for both alcoholic and non-alcoholic fatty liver disease to help protect liver cells and improve liver enzyme levels.

How long does Hepamac Tablet typically take to see improvement in liver function tests?

Most patients notice improvements in liver enzyme levels and symptoms within 4 to 8 weeks of regular Hepamac Tablet use, though individual responses vary based on the severity of liver condition.

Should Hepamac Tablet be taken before or after meals for best absorption?

Hepamac Tablet is usually taken after meals to enhance absorption and reduce any potential stomach discomfort, but follow your doctor's specific instructions.

Will Hepamac Tablet help with jaundice or yellowish skin discoloration?

Hepamac Tablet can help improve liver function, which may reduce jaundice over time, but you should consult your doctor for proper evaluation and comprehensive treatment.

Is Hepamac Tablet suitable for people recovering from hepatitis?

Yes, Hepamac Tablet is often recommended during and after hepatitis treatment to support liver recovery and protect against further liver damage.

Fact Box

Habit Forming

Therapeutic Class

GASTRO INTESTINAL

Related lab tests

Bilirubin Direct

Bilirubin Indirect

Bilirubin Total

Liver Function Test

References

Combs Jr. GF, McClung JP. The Vitamins: Fundamental Aspects in Nutrition and Health. 5th ed. Westborough, MA: Academic Press; 2017.
Jatwa R, Kar A, Jatwa R, Anand Kar. Protective effect of L-Ornithine-L-Aspartate and Silymarin on chemically induced kidney toxicity and thyroid dysfunction in mice. EXCLI Journal. 2008;7:139-50. [Accessed 21 Feb. 2020] (online) Available from:
L-Ornithine L-aspartate and silymarin. Zynapte Rxhive: [Accessed 17 Apr. 2026] (online). Available from:
L-Ornithine L-aspartate and silymarin. Zynapte Rxhive: [Accessed 17 Apr. 2026] (online). Available from:

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Manufacturer details

Name: A)JIneka Healthcare Pvt Ltd
Address: A)Sector 6B,IIE ,Ranipur ,Haridwar-249 403

Marketer details

Name: Unimac Pharmaceuticals Pvt Ltd
Address: 19,9th floor,Plot no.10, Vishal Tower Janak Puri, New Delhi-58

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Hepamac Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India