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Hepabig 100IU Injection helps to protect you against hepatitis B (a virus that damages the liver). It is used to prevent hepatitis B after exposure to contaminated blood through sexual contact, accidental needle prick injury, from an infected mother to her newborn or after a liver transplant.

Written By Dr. Anuj Saini, MMST, MBBS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 19 Jul 2026 | 01:04 AM (IST)
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General Information

Contains

Human Hepatitis B Immunoglobulin (100IU)

Marketer

Bharat Serums & Vaccines Ltd

Storage

Store in a refrigerator (2 - 8°C). Do not freeze.
The content is shown in English
Hepabig 100IU Injection image
Hepabig 100IU Injection image

Product introduction

Hepabig 100IU Injection is normally given along with the hepatitis B vaccine. It comes from human blood plasma and is given by an injection into a large muscle such as your thigh or buttock. Your doctor will inject the prescribed dose after analyzing your condition. It should be given as soon as possible after the risk of infection is identified. If it is delayed too long, it may not be effective. This medicine is not a vaccine and will not provide long-term protection from hepatitis B.

This medicine may sometimes cause side effects like flushing, gastrointestinal disturbance (stomach pain and upset, nausea, vomiting), headache, dizziness, and injection site reactions (pain, swelling, and redness). If you get any of these, or other reactions, or just feel unwell, you should tell your doctor. There may be ways of preventing or reducing these effects. Any serious reaction to the injection is rare. 

Before using it, you should tell your doctor if you have kidney disease, any problems with blood clotting and if you have recently had, or plan to have a vaccination. It is not known whether this medicine is completely safe during pregnancy or breastfeeding so please take advice from your doctor.

Uses of Hepabig Injection

Benefits of Hepabig Injection

Prevention of Hepatitis B infection
Hepabig 100IU Injection is used to protect against infection by the hepatitis B virus. Hepatitis B is an infection of the liver caused by a virus. It can be spread from a mother to her newborn baby, by sharing needles and other equipment during drug use, by having sex with an infected person, by having a tattoo or body piercing and by sharing contaminated toothbrushes or razors. Hepatitis B can be serious, but it does not always cause obvious symptoms.

Hepabig 100IU Injection is given by an injection into a muscle as soon as possible after exposure to a risk and will help prevent infection. It is recommended for all infants and children up to age 18 years and adults in high-risk groups. This medicine does not work if you already have hepatitis B.

Side effects of Hepabig Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Hepabig
  • Flushing (sense of warmth in the face, ears, neck and trunk)
  • Gastrointestinal disturbance
  • Headache
  • Dizziness
  • Injection site reactions (pain, swelling, redness)

How to use Hepabig Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Hepabig Injection works

Hepabig 100IU Injection provides protection against the hepatitis B virus by supplying antibodies. These antibodies recognize and neutralize the virus if it enters the body, helping to prevent the infection from developing, especially after exposure.

All substitutes for Hepabig 100IU Injection

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

  • Hepabig 100IU Injection is injected into the large muscle such as a buttock or thigh by a healthcare professional.
  • It should be given as soon as possible (within 48 hours) once you have been exposed to hepatitis B infection.
  • You must inform your doctor if you have received any vaccine recently.
  • You may get pain, itching, rash or discomfort at the site of the injection. Inform your doctor if it does not go away or bothers you.
  • Inform your doctor if you are pregnant, planning pregnancy or breastfeeding. 

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Hepabig 100IU Injection. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Hepabig 100IU Injection during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CAUTION
Hepabig 100IU Injection should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.
Driving

Driving

SAFE
Hepabig 100IU Injection does not usually affect your ability to drive.
Kidney

Kidney

SAFE IF PRESCRIBED
Hepabig 100IU Injection is probably safe to use in patients with kidney disease. Limited data suggest dose adjustment may not be needed.
Liver

Liver

SAFE IF PRESCRIBED
Hepabig 100IU Injection is safe to use in patients with liver disease. No dose adjustment is recommended.
All

Frequently asked questions

Hepatitis B is a liver infection caused by hepatitis B virus.
The virus is found in the blood or certain body fluids and is spread when blood or body fluid from an infected person enters the body of an uninfected person. This can occur in a variety of ways including unprotected sexual contact, using needles, medicines, poor infection control practices in medical settings, particularly with equipment to test blood sugar. It can also transmit from mother to baby during birth, if a person comes in contact with infected wounds or skin sores, when an infected person bites another person or by sharing personal-care items, such as razors or toothbrushes. Hepatitis B virus particles can be found on objects, even in the absence of visible blood. The virus can remain infectious and capable of spreading infection for a minimum of seven days outside the human body.
The symptoms of hepatitis B include yellowing of skin and white areas of the eyes, discoloration of urine, loss of appetite or nausea, bloated and tender belly, extreme tiredness, fever and pain in joints.
Hepabig 100IU Injection is usually a three-dose series. It is recommended for all individuals from newborn to children of 18 years of age. Hepabig 100IU Injection should be given to infants at birth in the hospital. All older children who did not get all the recommended doses of Hepabig 100IU Injection as an infant should complete their vaccine series as soon as possible. Adolescents and adults who are just starting their series will need two or three doses, depending on their age and the brand of vaccine used. Hepabig 100IU Injection may be given to anybody who needs to get protected against hepatitis B.
Yes, Hepabig 100IU Injection is safe. It is administered to infants, children, adolescents and adults. There are usually no major side effects seen with Hepabig 100IU Injection. However, consult your doctor before using it.

Fact Box

Chemical Class

Immunoglobulins

Habit Forming

No

Therapeutic Class

VACCINES

Action Class

Immunoglobulin
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Bharat Serums & Vaccines Ltd
Address: 17th Floor, Hoechst House, Nariman Point, Mumbai – 400 021, Maharashtra, India.

Vendor Details

Country of origin: South korea
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