Gabaprime Trio Tablet

Gabapentin (100mg)+ Methylcobalamin (750mcg)+ Nortriptyline (10mg)

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Gabaprime Trio Tablet is a prescription medicine used for the treatment of neuropathic pain. This medicine decreases pain by controlling calcium channel activity of the nerve cells. It also works by increasing the level of chemical messengers in the brain that help in regulating mood.

Written By Dr. Anuj Saini, MMST, MBBS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 27 Aug 2026 | 01:05 AM (IST)

₹137 MRP ₹149.068% off

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General Information

Contains

Gabapentin (100mg)+ Methylcobalamin (750mcg)+ Nortriptyline (10mg)

Marketer

Starus Pharmaceuticals

Storage

Store below 30°C

The content is shown in English

Product introduction

Gabaprime Trio Tablet can be taken with or without food. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration advised by your doctor. If you miss a dose of this medicine, take it as soon as you remember. Finish the full course of treatment even if you feel better. It is important not to stop taking this medicine suddenly as it may worsen your symptoms.

Some common side effects of this medicine are constipation, weight gain, increased heart rate, and dryness in mouth. It may also cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. This medicine may cause weight gain and to control it, you should have a balanced diet and exercise regularly. Let your doctor know if you develop any unusual changes in mood or behavior or suicidal thoughts during the treatment.

Before taking this medicine let your doctor know if you suffer from kidney or liver disease. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Uses of Gabaprime Trio Tablet

Treatment of Neuropathic pain

Benefits of Gabaprime Trio Tablet

Treatment of Neuropathic pain
Gabaprime Trio Tablet is a combination of medicines used to treat long-lasting (chronic) pain caused by nerve damage due to diabetes, shingles or spinal cord injury. It reduces pain and its associated symptoms such as mood changes, sleep problems, and tiredness. Gabapentin, an active ingredient of this medicine, is thought to work by interfering with pain signals that travel through the damaged nerves and the brain. It also contains nutritional supplements that improve nerve conduction.

Side effects of Gabaprime Trio Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Gabaprime Trio

Limited data available

How to use Gabaprime Trio Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Gabaprime Trio Tablet may be taken with or without food.

How Gabaprime Trio Tablet works

Gabaprime Trio Tablet is a combination of three medicines: Gabapentin, Methylcobalamin and Nortriptyline. Gabapentin is an alpha 2 delta ligand which decreases pain by modulating calcium channel activity of the nerve cells. Methylcobalamin is a form of vitamin B which helps in the production of myelin, a substance that protects nerve fibers and rejuvenates damaged nerve cells. Nortriptyline is a tricyclic antidepressant which increases the levels of chemical messengers (serotonin and noradrenaline) that stop the movement of pain signals in the brain. Together, they relieve neuropathic pain (pain from damaged nerves).

All substitutes for Gabaprime Trio Tablet

For information purposes only. Consult a doctor before taking any medicine.

Gabarich NT Tablet

by Crescent Therapeutics Ltd

₹17.8/tablet

30% costlier

Quick tips

Gabaprime Trio Tablet is used to treat certain types of long-lasting pain caused by damage to nerves.
Inform your doctor if you are taking any other pain-relieving medicines.
Along with taking this medicine, your doctor might advise you to undergo physiotherapy to get relief from pain.
Avoid taking antacids 2 hours before or after taking Gabaprime Trio Tablet as they make it harder for your body to absorb the medicine.

Safety advice

Alcohol

UNSAFE

Do not drink alcohol while you are taking this medicine. Gabaprime Trio Tablet may cause excessive drowsiness when taken with alcohol.

Pregnancy

CONSULT YOUR DOCTOR

The safety of Gabaprime Trio Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

UNSAFE

Gabaprime Trio Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

UNSAFE

Gabaprime Trio Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
As Gabaprime Trio Tablet may affect your alertness which may affect your ability to drive.

Kidney

CAUTION

Gabaprime Trio Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver

CAUTION

Gabaprime Trio Tablet should be used with caution in patients with severe liver disease. Dose adjustment may be needed.
Inform your doctor if you develop any signs and symptoms of jaundice while taking this medicine. Use of Gabaprime Trio Tablet is not recommended in patients with severe liver disease.

Frequently asked questions

What is Gabaprime Trio Tablet used for?

Gabaprime Trio Tablet is used to treat neuropathic pain. It helps relieve pain caused by nerve damage, such as from diabetes, shingles, spinal injuries, or chronic nerve diseases. It also works by increasing the level of chemical messengers in the brain that help regulate mood.

Who should avoid taking Gabaprime Trio Tablet?

People should avoid taking Gabaprime Trio Tablet if they are allergic to any ingredients present in it, have recently had a heart attack, have ongoing certain heart rhythm problems, or are taking MAO inhibitor medicines for psychiatric conditions.

Are there any serious side effects of Gabaprime Trio Tablet?

Although they are rare, serious side effects of Gabaprime Trio Tablet may include severe allergic reactions, worsening depression, suicidal thoughts, swelling, or issues with urination. Seek immediate help if these occur.

Can Gabaprime Trio Tablet affect mood or mental health?

Nortriptyline, present in Gabaprime Trio Tablet, may affect mood and cause emotional changes. Monitor for depression or suicidal thoughts and report any changes to your doctor promptly.

How long does Gabaprime Trio Tablet take to relieve pain?

The exact time Gabaprime Trio Tablet takes to relieve pain is not known. However, you may start to notice improvement in pain within a few weeks of continued use. The full benefit may take longer depending on the condition and its severity.

Fact Box

Habit Forming

Therapeutic Class

NEURO CNS

References

Gilron I, Bailey JM, Tu D, et al. Nortriptyline and gabapentin, alone and in combination for neuropathic pain: a double-blind, randomised controlled crossover trial. Lancet. 2009 Oct 10;374(9697):1252-61. [Accessed 30 Jan. 2026]. Available from:

User feedback

Patients taking Gabaprime Trio Tablet

Once A Day

82%

Thrice A Day

Twice A Day

What are you using Gabaprime Trio Tablet for?

Neuropathic pain

83%

Others

17%

How much was the improvement?

Excellent

83%

Average

17%

What were the side-effects while using Gabaprime Trio Tablet?

No Side Effect

100%

How do you take Gabaprime Trio Tablet?

With food

100%

Please rate Gabaprime Trio Tablet on price

Not Expensive

100%

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Starus Pharmaceuticals
Address: STARUS PHARMACEUTICALS PRIVATE LIMITED, 1st FLOOR, MOPARTHY TOWERS, LANE BESIDE KARACHI BAKERY, ROAD NO:1, BANJARA HILLS, HYDERABAD-500034, INDIA

Vendor Details

Country of origin: India

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Gabaprime Trio Tablet

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Gabaprime Trio Tablet

Benefits of Gabaprime Trio Tablet

Side effects of Gabaprime Trio Tablet

How to use Gabaprime Trio Tablet

How Gabaprime Trio Tablet works

All substitutes for Gabaprime Trio Tablet

Gabarich NT Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

What is Gabaprime Trio Tablet used for?

Who should avoid taking Gabaprime Trio Tablet?

Are there any serious side effects of Gabaprime Trio Tablet?

Can Gabaprime Trio Tablet affect mood or mental health?

How long does Gabaprime Trio Tablet take to relieve pain?

Fact Box

Habit Forming

Therapeutic Class

References

User feedback

Patients taking Gabaprime Trio Tablet

What are you using Gabaprime Trio Tablet for?

How much was the improvement?

What were the side-effects while using Gabaprime Trio Tablet?

How do you take Gabaprime Trio Tablet?

Please rate Gabaprime Trio Tablet on price

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

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