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Fluticone-OX Nasal Spray

Fluticasone Furoate (0.028% w/w)+ Oxymetazoline (0.050% w/w)

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Fluticone-OX Nasal Spray is a combination medicine used in the treatment of allergy symptoms, such as runny nose, stuffy nose, sneezing, watery eyes, and congestion or stuffiness.

Written By Dr. Anuj Saini, MMST, MBBS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 11 Oct 2026 | 01:04 AM (IST)

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7 gm Nasal Spray

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General Information

Contains

Fluticasone Furoate (0.028% w/w)+ Oxymetazoline (0.050% w/w)

Marketer

Zydus Healthcare Limited

Storage

Store below 30°C

The content is shown in English

Product introduction

Fluticone-OX Nasal Spray should be used as advised by your doctor. Do not use it more often or for longer than recommended. Normally you should blow your nose gently before using it, keep one nostril closed while applying the medicine into the other, and then sniff hard to make sure it reaches deep into the nose. Then repeat for the other nostril. It provides relief very quickly and can last for several hours. If you use this medicine too often or for too long, it may worsen your symptoms rather than improve them. It is also beneficial to have plenty of fluids while taking this medication.

The most common side effects are taste change, nosebleeds, and headaches. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects.

Never support self-medication or recommend your medicine to another person. Before you start taking this medicine it is important to inform your doctor if you are suffering from liver or kidney disease. You should also tell your doctor if you are pregnant, planning pregnancy, or breastfeeding.

Uses of Fluticone-OX Nasal Spray

Treatment of Sneezing and runny nose due to allergies

Benefits of Fluticone-OX Nasal Spray

Treatment of Sneezing and runny nose due to allergies
Fluticone-OX Nasal Spray provides relief from symptoms such as blocked or runny nose, sneezing, and itchy or watery eyes. This will make it easier for you to go about your daily activities. It rarely has any serious side effects and you may only need to take it on days you have symptoms. Moreover, Fluticone-OX Nasal Spray makes you feel less sleepy as compared to other antihistamine medicines. If you are taking it to prevent symptoms, use it regularly to get the most benefits.

Side effects of Fluticone-OX Nasal Spray

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Fluticone-OX

Headache
Dry nose
Fever

How to use Fluticone-OX Nasal Spray

Use this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Insert the bottle tip into one nostril and close the other nostril. Direct the spray towards the sides of your nostril, away from the cartilage dividing the two sides of your nose. As you spray, breath gently and keep the head upright. Repeat the same process for the other nostrils.

How Fluticone-OX Nasal Spray works

Fluticone-OX Nasal Spray is a combination of two medicines. Fluticasone furoate inhibits an enzyme (cytosolic phospholipase A2) that triggers a series of reactions involved in the production of inflammatory mediators, such as prostaglandins and leukotrienes. Dilated blood vessels can cause nasal congestion. Oxymetazoline is a decongestant that shrinks blood vessels in the nasal passages.

Quick tips

Use the medication exactly as prescribed by your doctor.
Do not use more than directed. Frequent or prolonged use may cause nasal congestion to recur or worsen.
Do not swallow.
Use of same Fluticone-OX Nasal Spray by more than one person may spread infection.
Use the medication exactly as prescribed by your doctor.
Do not use more than directed. Frequent or prolonged use may cause nasal congestion to recur or worsen.
Do not swallow.
Use of same Fluticone-OX Nasal Spray by more than one person may spread infection.

Safety advice

Alcohol

No interaction found/established

Pregnancy

CONSULT YOUR DOCTOR

Fluticone-OX Nasal Spray is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

CONSULT YOUR DOCTOR

Fluticone-OX Nasal Spray may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

No interaction found/established

Kidney

No interaction found/established

Liver

No interaction found/established

Frequently asked questions

What is Fluticone-OX Nasal Spray used for?

Fluticone-OX Nasal Spray is used to treat allergic rhinitis (hay fever) with moderate-to-severe nasal congestion. It provides relief from symptoms like a blocked or stuffy nose, sneezing, a runny nose, and sinus pressure.

How is Fluticone-OX Nasal Spray administered, and why is the nasal route effective?

Fluticone-OX Nasal Spray is a nasal spray applied directly into the nostrils. This topical route delivers the medicine right where it is needed, providing fast, local action in the nasal passages with minimal absorption into the rest of the body.

I have heard you should not use decongestant sprays for more than few days. Is that true for this Fluticone-OX Nasal Spray?

While that is true for most decongestant-only sprays due to the risk of rebound congestion (worsening stuffiness), studies on combination products present in Fluticone-OX Nasal Spray show it can be used safely for longer periods (e.g., up to 28 days) because the fluticasone (a steroid) in Fluticone-OX Nasal Spray helps prevent that from happening. However, the dose and duration are solely advised by your doctor based on your condition and severity.

How quickly can I expect relief from a severely blocked nose after using Fluticone-OX Nasal Spray?

You can expect relief from nasal congestion within a few minutes after using Fluticone-OX Nasal Spray. The full benefits may take longer.

When is Fluticone-OX Nasal Spray a better option than a regular steroid-only nasal spray?

Fluticone-OX Nasal Spray is particularly useful when a steroid-only nasal spray alone is not enough to control your stuffy nose. It is formulated for those with moderate-to-severe congestion that significantly impacts their daily life and sleep.

Can Fluticone-OX Nasal Spray help me sleep better?

By providing effective and long-lasting relief from nasal congestion, Fluticone-OX Nasal Spray can significantly improve sleep quality for people whose allergies or stuffiness keep them awake at night.

Can I stop using Fluticone-OX Nasal Spray as soon as I feel better?

For best results, you should complete the full course of Fluticone-OX Nasal Spray treatment as prescribed by your doctor. Stopping early may cause your symptoms to return.

Will Fluticone-OX Nasal Spray cause nosebleeds or dryness?

Some users may experience mild dryness or irritation in the nose after using Fluticone-OX Nasal Spray. To minimize this, ensure you are using the correct spray technique and not aiming the nozzle directly at the nasal septum (the wall between your nostrils).

Fact Box

Habit Forming

Therapeutic Class

RESPIRATORY

References

Kumar RS, Jain MK, Kushwaha JS, et al. Efficacy and Safety of Fluticasone Furoate and Oxymetazoline Nasal Spray: A Novel First Fixed Dose Combination for the Management of Allergic Rhinitis with Nasal Congestion. J Asthma Allergy. 2022 Jun 10;15:783-792. [Accessed 05 Jan. 2026]. Available from:

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Zydus Healthcare Limited
Address: Zydus Tower, CTS No- 460/6 of Village Pahadi, Off I. B. Patel Road, Goregaon (East), Mumbai-400 063 / (Unit II), 967 (P), 968 (P), 970 (P), Duga Circle, Kamarey Bhasmay, Kumrek, Sikkim - 737132

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Fluticone-OX Nasal Spray. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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Home

Respiratory

Topical Nasal Preparations Steroidal

Fluticone-OX Nasal Spray

Fluticone-OX Nasal Spray

Payment, Returns & Expiry

Cash on delivery available

7 day free return

Product expires after Mar, 2027

Price Info

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Fluticone-OX Nasal Spray

Benefits of Fluticone-OX Nasal Spray

Side effects of Fluticone-OX Nasal Spray

How to use Fluticone-OX Nasal Spray

How Fluticone-OX Nasal Spray works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

What is Fluticone-OX Nasal Spray used for?

How is Fluticone-OX Nasal Spray administered, and why is the nasal route effective?

I have heard you should not use decongestant sprays for more than few days. Is that true for this Fluticone-OX Nasal Spray?

How quickly can I expect relief from a severely blocked nose after using Fluticone-OX Nasal Spray?

When is Fluticone-OX Nasal Spray a better option than a regular steroid-only nasal spray?

Can Fluticone-OX Nasal Spray help me sleep better?

Can I stop using Fluticone-OX Nasal Spray as soon as I feel better?

Will Fluticone-OX Nasal Spray cause nosebleeds or dryness?

Fact Box

Habit Forming

Therapeutic Class

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

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