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Flexirest-D Tablet is a combination medicine used in the treatment of pain due to muscle spasms. It improves the movement of muscles and provides relief from pain and discomfort associated with muscle spasms.

Written By Dr. Lipika Khurana, PGDHHM, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 25 Nov 2025 | 03:07 PM (IST)
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Flexirest-D Tablet image
Flexirest-D Tablet image
Flexirest-D Tablet image

Product introduction

Flexirest-D Tablet is best taken in an empty stomach. You should take it regularly as advised by your doctor. Do not take more or use it for longer duration than recommended by your doctor.

Some of the common side effects on of this medicine includes nausea, vomiting, stomach pain, heartburn, diarrhea, sleepiness, and loss of appetite. If any of these side effects bother you or do not go away with time, you should let your doctor know. Your doctor may help with ways to reduce or prevent these side effects.

The medicine may not be suitable for everybody. Before taking it, let your doctor know if you have any problems with your heart, kidneys, and liver. To make sure it is safe for you, let your doctor also know all the other medicines you are taking. Pregnant and breastfeeding mothers should first consult their doctors before using the medicine.

Uses of Flexirest-D Tablet

  • Treatment of Pain due to muscle spasm

Benefits of Flexirest-D Tablet

Treatment of Pain due to muscle spasm
Flexirest-D Tablet is a combination medicine that contains a painkiller as well as a muscle relaxant. It is used to relieve pain, inflammation, and swelling in conditions that affect muscles. Also, it effectively relieves muscle stiffness or spasm, thereby improving muscle movement. It works by blocking chemical messengers in the brain that tell us we have pain.
Take Flexirest-D Tablet as prescribed by the doctor to get the most benefit. Do not take more or for longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time. This will help you to go about your daily activities more easily and have a better, more active, quality of life.

Side effects of Flexirest-D Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Flexirest-D
  • Nausea
  • Vomiting
  • Stomach pain/epigastric pain
  • Heartburn
  • Diarrhea
  • Sleepiness
  • Loss of appetite

How to use Flexirest-D Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Flexirest-D Tablet is to be taken on an empty stomach.

How Flexirest-D Tablet works

Flexirest-D Tablet is a combination of two medicines: Diclofenac and Metaxalone, which relieves pain and relaxes the muscles.Diclofenac is a non-steroidal anti-inflammatory drug (NSAID) which works by blocking the release of certain chemical messengers that cause pain and inflammation (redness and swelling). Metaxalone is a muscle relaxant. It works on the centers in the brain and spinal cord to relieve muscle stiffness or spasm. It relieves pain and improves the movement of muscles.

Quick tips

  • Flexirest-D Tablet helps relieve pain and muscle spasm that may occur due to strains, sprains, and muscle injuries.
  • It is usually used along with rest and physical therapy.
  • It may cause dizziness. Do not drive or do anything requiring concentration until you know how it affects you.
  • Avoid consuming alcohol when taking Flexirest-D Tablet as it may cause excessive drowsiness.

Safety advice

Alcohol

Alcohol

UNSAFE
It is unsafe to consume alcohol with Flexirest-D Tablet
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Flexirest-D Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Flexirest-D Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving

Driving

UNSAFE
Flexirest-D Tablet may cause side effects that could affect your ability to drive.
Kidney

Kidney

CAUTION
Flexirest-D Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Liver

Liver

CAUTION
Flexirest-D Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.
Regular monitoring of liver function tests is recommended in patients with liver disease if this medicine is to be taken for a long time.

Frequently asked questions

Flexirest-D Tablet is a combination of two medicines: Diclofenac and Metaxalone. This combination helps to relieve muscle pain. It works by relaxing muscles by acting on central nervous system and lowering chemical substance in the body that causes pain and inflammation.
Flexirest-D Tablet is usually used for short term and can be discontinued when your pain is relieved. However, Flexirest-D Tablet should be continued if your doctor has advised you to do so.
Yes, the use of Flexirest-D Tablet can cause nausea and vomiting. Taking it with milk, food or with antacids can prevent nausea. Avoid taking fatty or fried foods along with this medication. In case of vomiting, drink plenty of water or other fluids. Talk to your doctor if vomiting persists and you notice signs of dehydration like dark colored and strong-smelling urine and a low frequency of urination. Do not take any other medicine without consulting a doctor.
Yes, the use of Flexirest-D Tablet can cause dizziness (feeling faint, weak, unsteady or lightheaded) in some patients. If you feel dizzy or lightheaded, it is better to rest for some time and resume once you feel better.
The use of Flexirest-D Tablet is considered to be harmful for patients with known allergy to painkillers (NSAIDs) or any of the components or excipients of this medicine. The use of this medicine should preferably be avoided in patients with a history of stomach ulcers or in patients who have active, recurrent stomach ulcer / bleeding. It should also be avoided in patients with a history of heart failure, high blood pressure, or any underlying liver or kidney disease.
Yes, the long-term use of Flexirest-D Tablet can cause damage to the kidneys. Normal kidneys produce a chemical called prostaglandins that protects them from damage. Use of painkillers lower the levels of prostaglandins in the body which leads to kidney damage on long-term use. Use of painkillers is not recommended in patients with underlying kidney disease.

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Manufacturer details

Name: Logos pharma
Address: Maissa Tibba, Nalagarh Solan,H.P-174101

Marketer details

Name: Curador Healthcare Pvt Ltd
Address: Corp. Off. Regus Platinum,Level 13, Platinum Techno Park, Plot No 17 and 18, Sec 30A , Vashi, Navi Mumbai - 400705

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Flexirest-D Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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