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Flakeoff Shampoo is a combination medicine used in the treatment of dandruff which also provides a shiny appearance to the hair. It works by killing microorganisms that cause infection.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 12 Mar 2026 | 12:43 PM (IST)
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Flakeoff Shampoo image
Flakeoff Shampoo image

Product introduction

Flakeoff Shampoo is only meant for external use and should be used as advised by your doctor. This medicine should be used regularly to get the most benefit from it. Do not use more than you need it will not clear your condition faster and may only increase the side effects. Make sure not to leave it on scalp for more than of 5 minutes.  If it gets into your eyes, nose, or mouth rinse with water.

This medicine is usually safe, however, it may cause burning, irritation, itching, and redness at the application site. These side effects are usually mild and self-limiting. Serious side effects are rare.

It is not likely that other medicines you take by mouth or injection will affect the way this medicine works, but talk to your doctor before using it if you have recently used another medicine for dandruff. The medicine is not recommended for pregnant women. Pregnant and breastfeeding mothers should consult their doctors before using this medicine.

Uses of Flakeoff Shampoo

Benefits of Flakeoff Shampoo

Treatment of Dandruff
Flakeoff Shampoo is used to control dandruff and gives relief from scaly, flaky, and itchy scalp. It is an antifungal and works by killing and stopping the growth of fungus that causes dandruff. Massage it on your scalp and leave it on for a few minutes before rinsing it off. Make sure you complete the full course of treatment. This will ensure that the infection is completely cured and prevent it from returning.

Side effects of Flakeoff Shampoo

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Flakeoff
  • Application site reactions (burning, irritation, itching and redness)

How to use Flakeoff Shampoo

Use it as advised by your doctor or check the label for directions before use.

How Flakeoff Shampoo works

Flakeoff Shampoo is a combination of two antifungal medicines: Ketoconazole and Piroctone Olamine which treat dandruff. Ketoconazole kills fungi by destroying the fungal cell membrane. Piroctone Olamine works by penetrating the cell membrane of the fungi to interfere with their energy metabolism and oxygen uptake. This kills the fungi and clears up the infection.

All substitutes for Flakeoff Shampoo

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

  • Do not use this medicine more often or for longer than advised by your doctor.
  • Leave the shampoo on for three to five minutes before rinsing.
  • Avoid getting it in the eyes, mouth or nose. Rinse with cold water if you accidentally get it in these areas.
  • Stop using Flakeoff Shampoo and inform your doctor if you notice any irritation or any other skin infection.
  • Inform your doctor if the treated skin area does not improve after 2-4 weeks of treatment.
  • Your usual shampoo can be used as necessary between treatment with this medicine.

Safety advice

Alcohol

Alcohol

No interaction found/established
Pregnancy

Pregnancy

No interaction found/established
Breast feeding

Breast feeding

No interaction found/established
Driving

Driving

No interaction found/established
Kidney

Kidney

No interaction found/established
Liver

Liver

No interaction found/established

Frequently asked questions

Flakeoff Shampoo is mainly used for dandruff, itchy scalp, and seborrheic dermatitis, helping with flaking, redness, and scalp irritation.
Flakeoff Shampoo helps control dandruff and irritation, which can lower hair fall and set the foundation for healthy hair growth. However, if your hair fall is severe without any scalp issues, talk to a doctor, as you might need a specific treatment for hair growth.
Flakeoff Shampoo is usually recommended 2 to 3 times per week, but always follow your doctor’s or the product’s instructions for best results.
The exact time Flakeoff Shampoo takes to show improvement is not known. However, the itching and flaking often start improving within a few days. Several weeks may be needed for full benefits and hair growth support.
Yes, by controlling fungus and reducing excess oil (sebum), Flakeoff Shampoo helps calm an oily scalp and keeps hair fresher.
Most people can use Flakeoff Shampoo even with color-treated hair. However, if you have concerns, ask your stylist or dermatologist first.
Yes, Flakeoff Shampoo is designed to relieve both itching and redness by fighting irritation and fungal growth.
Yes, a gentle conditioner is fine to use after washing your hair with Flakeoff Shampoo. However, avoid harsh treatments on the same day.
If symptoms return, your doctor might recommend restarting or maintaining regular use of Flakeoff Shampoo to prevent recurrence.
Flakeoff Shampoo helps reduce dandruff-related hair thinning by keeping the scalp healthy. Some studies show it helps increase hair diameter and growth over time.

Fact Box

Habit Forming

No

Therapeutic Class

DERMA

References

  1. Piérard-Franchimont C, Goffin V, Henry F, Uhoda I, et al. Nudging hair shedding by antidandruff shampoos. A comparison of 1% ketoconazole, 1% piroctone olamine and 1% zinc pyrithione formulations. Int J Cosmet Sci. 2002;24(5):249-56. [Accessed 27 Feb. 2020] (online) Available from:
  2. Bennett JE. Antimicrobial Agents: Anifungal Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. pp. 1225-1241.
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Transcend Therapeutics Pvt Ltd
Address: NEW NO 5,OLD NO 11,PART B BACK PORTION 24TH STREET, NANGANALLUR CHENNAI Chennai TN 600061 INDIA

Vendor Details

Country of origin: India
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