


Exiride 2.5mg/50mg Tablet
Amiloride (2.5mg)+ Hydrochlorothiazide (50mg)
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Exiride 2.5mg/50mg Tablet is a combination of two medicines used to treat hypertension (high blood pressure). It reduces excess fluid levels in your body and maintains the potassium balance in the body. This medicine makes you lose excess water through urine.
Written By Dr. Swati Mishra, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 08 Aug 2026 | 01:01 AM (IST)
Written By Dr. Swati Mishra, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 08 Aug 2026 | 01:01 AM (IST)
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General Information
Contains
Amiloride (2.5mg)+ Hydrochlorothiazide (50mg)
Marketer
Zee Laboratories
Storage
Store below 30°C
The content is shown in English



Product introduction
It is best to take Exiride 2.5mg/50mg Tablet in the morning along with food in order to avoid frequent urination at night time. For better results, it is suggested to take it at the same time every day. The dose and how often you take it depends on what you are taking it for. Your doctor will decide how much you need to improve your symptoms. You should take this medicine for as long as it is prescribed for you.
Nausea, vomiting, diarrhea, and dehydration are very common side effect of this medicine. It might lower down the level of calcium, sodium, and magnesium in the blood. Hence, regular monitoring of kidney function and electrolytes is important while using this medicine. It might cause dizziness or tiredness if happens rise slowly from sitting position or avoid driving.
Before taking this medicine, tell your doctor if you have any liver or kidney disease. It is generally safe to use during pregnancy or breastfeeding. You should also let your healthcare team know all other medicines you are taking as they may affect, or be affected by this medicine.
Nausea, vomiting, diarrhea, and dehydration are very common side effect of this medicine. It might lower down the level of calcium, sodium, and magnesium in the blood. Hence, regular monitoring of kidney function and electrolytes is important while using this medicine. It might cause dizziness or tiredness if happens rise slowly from sitting position or avoid driving.
Before taking this medicine, tell your doctor if you have any liver or kidney disease. It is generally safe to use during pregnancy or breastfeeding. You should also let your healthcare team know all other medicines you are taking as they may affect, or be affected by this medicine.
Uses of Exiride Tablet
Benefits of Exiride Tablet
Hypertension (high blood pressure)
Exiride 2.5mg/50mg Tablet relaxes the blood vessels so that blood can flow more easily around your body. It also eliminates excess water from the body and increases urine output. This maintains balance of electrolytes (like potassium), lowers your blood pressure and reduces your risk of having a stroke, a heart attack, or kidney problems in the future. You do not usually feel any direct benefit from taking this medicine, but it works in the long term to keep you well. You should take it regularly as prescribed for this medicine to be most effective, even if you feel better.
Exiride 2.5mg/50mg Tablet relaxes the blood vessels so that blood can flow more easily around your body. It also eliminates excess water from the body and increases urine output. This maintains balance of electrolytes (like potassium), lowers your blood pressure and reduces your risk of having a stroke, a heart attack, or kidney problems in the future. You do not usually feel any direct benefit from taking this medicine, but it works in the long term to keep you well. You should take it regularly as prescribed for this medicine to be most effective, even if you feel better.
Side effects of Exiride Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Exiride
- Headache
- Dizziness
- Rash
- Decreased appetite
How to use Exiride Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Exiride 2.5mg/50mg Tablet should be taken with or after food.
How Exiride Tablet works
Exiride 2.5mg/50mg Tablet is a combination of two diuretics: Amiloride and Hydrochlorothiazide.
Quick tips
- Take it in the morning with breakfast to avoid getting up at night to urinate.
- It can make you feel dizzy for the first few days. Do not drive or do anything requiring concentration until you know how Exiride 2.5mg/50mg Tablet affects you.
- It may increase the level of potassium in your blood. Avoid taking potassium supplements and potassium-rich foods such as banana and broccoli.
- Notify your doctor if you experience diarrhea, vomiting, fast or irregular heartbeat, swelling in feet, or difficulty breathing.
- Monitor your blood pressure after starting Exiride 2.5mg/50mg Tablet, and notify your doctor if it does not lower down.
Safety advice

Alcohol
CAUTION
Alcohol should be used with caution while taking Exiride 2.5mg/50mg Tablet.

Pregnancy
CONSULT YOUR DOCTOR
Exiride 2.5mg/50mg Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding
UNSAFE
Exiride 2.5mg/50mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving
UNSAFE
Exiride 2.5mg/50mg Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney
UNSAFE
Exiride 2.5mg/50mg Tablet is unsafe to use in patients with kidney disease and should be avoided.
Use of Exiride 2.5mg/50mg Tablet is not recommended in patients with severe kidney disease.
Use of Exiride 2.5mg/50mg Tablet is not recommended in patients with severe kidney disease.

Liver
UNSAFE
Exiride 2.5mg/50mg Tablet is unsafe to use in patients with liver disease and should be avoided.
Frequently asked questions
No, keep using Exiride 2.5mg/50mg Tablet as advised by your doctor, even if you feel well. Stopping Exiride 2.5mg/50mg Tablet suddenly may lead to serious complications such as heart attack and stroke.
Your doctor will check your blood potassium levels periodically for high potassium levels. Make sure that you do not miss any future appointments with the doctor.
Keep this medicine in the packet or the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
Yes, the use of Exiride 2.5mg/50mg Tablet can cause dry mouth. If you experience dry mouth, drink plenty of water. Take regular sips during the day and keep some water by your bed at night. You may use lip balm if your lips are also dry. Try to avoid foods that are acidic (like lemons), spicy and salty.
Yes, the use of Exiride 2.5mg/50mg Tablet can make you feel dizzy. This may occur when you suddenly rise up from lying or sitting position. To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
Fact Box
Habit Forming
No
Therapeutic Class
CARDIAC
Related lab tests
References
- DailyMed. Amiloride hydrochloride and hydrochlorothiazide. [Accessed 11 Apr. 2019] (online) Available from:
- Amiloride Hydrochloride and Hydrochlorothiazide. Wrexham, Wales: CP Pharmaceuticals Ltd.; 2018. [Accessed 11 Apr. 2019] (online) Available from:
- MedlinePlus. Amiloride and Hydrochlorothiazide. [Accessed 11 Apr. 2019] (online) Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
Marketer details
Name: Zee Laboratories
Address: Uchani, G.T. Road, Karnal-132001 Haryana (INDIA)
Address: Uchani, G.T. Road, Karnal-132001 Haryana (INDIA)
Vendor Details
Country of origin: India
Lab tests offered by us
- CBC (Complete Blood Count)
- FBS (Fasting Blood Sugar)
- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- PPBS (Postprandial Blood Sugar)
- Lipid Profile
- Vitamin D (25-Hydroxy)
- Urine R/M (Urine Routine & Microscopy)
- Coronavirus Covid -19 test- RT PCR
- LFT (Liver Function Test)
- KFT (Kidney Function Test)
- TSH (Thyroid Stimulating Hormone) Ultrasensitive
- ESR (Erythrocyte Sedimentation Rate)
- Uric Acid, Serum
- Vitamin B12
- CRP (C-Reactive Protein), Quantitative
- Urine C/S (Urine Culture and Sensitivity)
- Serum Electrolytes
- Serum Calcium
- Serum Creatinine
- Diabetes Screening (HbA1C & Fasting Sugar)
- KFT with Electrolytes (Kidney Function Test with Electrolytes)
- Cholesterol - Total
- Hb (Hemoglobin)
- Complete Hemogram (CBC & ESR)
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