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ESPRA XN TABLET

Tablet
Rs.120for 1 strip(s) (10 tablets each)
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Composition FOR ESPRA XN

Naproxen(375mg),Esomeprazole(20mg)

food interaction for ESPRA XN

alcohol interaction for ESPRA XN

pregnancy interaction for ESPRA XN

lactation interaction for ESPRA XN

food
alcohol
pregnancy
lactation
There is no data available. Please consult doctor before consuming the drug.
Taking Naproxen with alcohol can increase the risk of stomach bleeding caused by naproxen.
Taking a large amount of alcohol can increase acidity and cause acid reflux in the food pipe causing heartburn. This would decrease the effect of this drug and can aggravate your underlying condition.
UNSAFE
Espra xn tablet may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
WEIGH RISKS VS. BENEFITS
Unknown. Human and animal studies are not available. Please consult your doctor.

SALT INFORMATION FOR ESPRA XN

Naproxen(375mg)

Uses

Naproxen is used in fever, headache, arthralgia, myalgia, dental pain, post operative pain, pain during menstruation, osteoarthritis, rheumatoid arthritis, ankylosing spondylitis and gout.

How it works

Naproxen is a non-steroidal anti-inflammatory drug (NSAID). It works by blocking the release of certain chemical messengers that cause fever, pain and inflammation (redness and swelling).

Common side effects

Esomeprazole(20mg)

Uses

Esomeprazole is used in the treatment of acidity, heartburn, intestinal ulcers and stomach ulcers.

How it works

Esomeprazole lowers the acid production in the stomach.

Common side effects

Nausea, Abdominal pain, Constipation, Diarrhoea, Flatulence

COMMON DOSAGE FOR ESPRA XN TABLET

Patients taking ESPRA XN TABLET

  • 54%
    Once A Day
  • 38%
    Twice A Day
  • 5%
    Thrice A Day
  • 2%
    Twice A Week
  • 2%
    Four Times A Day

SUBSTITUTES FOR ESPRA XN

No substitutes found

Top Rheumatologists

Expert advice FOR ESPRA XN

Do not take this medicine.
  • If you are allergic to naproxen, aspirin or other NSAID or any other ingredient in the medicine.
  • if you have gastric ulcer or bleeding or black sticky stools, or have had such complaints after taking any NSAID in the past.
Do not drive or use machines after taking naproxen if you experience drowsiness, dizziness, vertigo, sleeplessness, tiredness, visual disturbances.This medicine can interfere with certain blood and urine test results so it is advised that patient should tell doctor beforehand about usage of this drug.Women should not take this medicine if they want to become pregnant.Take the lowest amount for the shortest possible time to reduce the risk of heart attack or stroke associated with this medicine. Do not take this medicine consecutively for more than 3 days during one menstrual cycle.

Frequently asked questions FOR ESPRA XN

Naproxen

Q.

Does naproxen help with pain?
Naproxen is a pain killer and is used to reduce pain. It belongs to a group of medicines called non-steroidal anti-inflammatory drugs (NSAIDs) and is used to treat diseases of joints such as rheumatoid arthritis (including in children), osteoarthritis, ankylosing spondylitis. It is also used to treat attacks of gout, muscle and bone disorders and painful periods.

Q.

Can I take naproxen for a sinus infection?
Naproxen may be given to reduce the pain and swelling associated with sinus infection. It does not, however, treat any infections, you would need antibiotics for the same. Consult a doctor for the treatment of sinus infection.

Q.

Does naproxen raise blood pressure?
Naproxen can raise your blood pressure, however, it is not a very common side effect. Talk to your doctor if you are a hypertensive (patient of high blood pressure) and you have been asked to take naproxen or you experience high blood pressure while taking naproxen.

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Q.

Does naproxen cause constipation?
Naproxen can cause constipation, however, it is not a very common side effect. Talk to your doctor before if you experience constipation while taking naproxen.

Q.

Does naproxen contain sulfa?
Naproxen doesn't contain any sulfa substance.

Q.

Is naproxen a controlled substance?
Naproxen is not a controlled substance, however, it is available only when prescribed by a doctor.

Q.

Is naproxen addictive?
Naproxen has not been reported to have any addictive potential.

Q.

Does naproxen contain caffeine?
Naproxen does not contain any caffeine.

Q.

Is naproxen safe?
Naproxen is safe if used at prescribed doses for the prescribed duration as advised by your doctor.

Q.

Is naproxen a narcotic?
Naproxen is not a narcotic medicine. It is a painkiller and belongs to the group of medicines called non-steroidal anti-inflammatory drugs (NSAIDs).

Q.

Is naproxen safe in pregnancy?
Naproxen should not be taken during pregnancy. If you are pregnant or you are planning to have a baby, tell your doctor before taking this medicine.

Q.

Is naproxen a blood thinner?
Naproxen is not a blood thinner. It is a painkiller and belongs to the group of medicines called non-steroidal anti-inflammatory drugs (NSAIDs).

Q.

Is naproxen good for headaches?
Naproxen can help in relieving a headache and has been used for treating migraine headaches. However, it has not been found to be very effective for the relief of migraine headaches as mentioned in some studies. Consult a doctor before taking any medicines for the relief of headache.

Q.

Is naproxen over the counter?
Naproxen is not an over the counter (OTC) product. It belongs to a class of prescription drugs.

Q.

Is naproxen better than ibuprofen?
Naproxen and ibuprofen belong to the same class of medicines called non-steroidal anti-inflammatory drugs (NSAIDs) and has a similar way of working, but their effect may vary upon individual response. Always follow doctor's advice regarding its use.

Q.

Can I take naproxen with ibuprofen?
Naproxen and ibuprofen both belong to the class of drugs known as nonsteroidal anti-inflammatory drugs (NSAIDs). When used together, they can cause coagulation problems (increased tendency for bleeding) and can also increase blood potassium levels. Please consult your doctor before taking these two medicines together.

Q.

Can I take naproxen with paracetamol?
Naproxen can be taken with paracetamol. No drug-drug interactions have been reported between the two. However, interactions can occur. Please consult your doctor before taking the two medicines together.

Q.

Can I take naproxen with meloxicam?
Meloxicam and naproxen both belong to the class of drugs known as nonsteroidal anti-inflammatory drugs (NSAIDs) When used together, they can cause coagulation problems (increased tendency for bleeding) and can also increase blood potassium levels. Please consult your doctor before taking these two medicines together.

Q.

Can I take naproxen with oxycodone?
Naproxen can be taken with oxycodone. No drug-drug interactions have been reported between the two. However, interactions can occur. Please consult your doctor before taking the two medicines together.

Q.

Can I take naproxen with codeine?
Naproxen can be taken with codeine. No drug-drug interactions have been reported between the two. However, interactions can occur. Please consult your doctor before taking the two medicines together.

Q.

Can I take naproxen with prednisone?
Naproxen and prednisone can increase the toxicity of each other. Talk to your doctor before taking the two medicines together.

Q.

Can I take naproxen with tramadol?
Naproxen can be taken with tramadol. No drug-drug interactions have been reported between the two. However, interactions can occur. Please consult your doctor before taking the two medicines together.

Q.

Can I take naproxen for cramps (painful periods)?
Naproxen can be used for treating cramps (painful periods). Talk to your doctor before taking any medicines for cramps.

Q.

Can I take naproxen for fever?
Naproxen is not generally used to treat fever. It is a pain-killer and is used for treating various painful conditions. Consult a doctor if you have a fever as it is important to know the cause of fever before starting any medicines.

Q.

Can I take naproxen for back pain?
Naproxen can be used to treat muscle and bone disorders, so, it can help in relieving back pain. However, consult a doctor for the relief of back pain as it is important to find out the cause of back pain before starting any medicines.

Q.

Can I take naproxen for a cold?
Naproxen is not used to treat cold. Consult a doctor if you have a cold before taking any medicine.

Q.

Can I take naproxen for a hangover?
Naproxen is not used to treat a hangover.

Q.

Can I take naproxen for gallbladder pain?
Naproxen is not used to treat gallbladder pain. Consult a doctor if you think you have gall bladder pain as it is important to know the reason for pain before starting any medicines.

Q.

Can I take naproxen for tonsillitis?
Naproxen is not used to treat tonsillitis. Consult a doctor if you think you have tonsillitis as it would need to be diagnosed before the start of any treatment.

Q.

Can I take naproxen for urinary tract infection (UTI)?
Naproxen is not used to treat urinary tract infection (UTI) as it is a pain killer and you would need an antibiotic for the treatment of an infection. Please consult your doctor if you think you have urinary tract infection (UTI) as it requires proper diagnosis and treatment.

Q.

Can I take naproxen for a toothache (dental pain)?
Naproxen is a pain killer, so can be used for the treatment of a toothache (dental pain), however, please consult your doctor before starting any painkillers as there could be an underlying infection which needs to be taken care of along with.

Q.

Does naproxen make you sleepy?
Naproxen may make you feel dizzy, drowsy or tired and may cause blurred vision and you need to be careful while driving or operating any machinery. Talk to your doctor before taking naproxen.

Q.

Does naproxen work immediately?
Naproxen starts working immediately as it is absorbed quickly from the gastrointestinal tract. Some pain relief occurs after a few hours, however, the full effect is seen after a couple of weeks. Please consult your doctor for more details.

Q.

Does naproxen expire?
Yes, naproxen does expire. All the medicines come with an expiry date mentioned on the pack. You must check the expiry date before using any medicine.

Q.

Does naproxen have aspirin in it?
Naproxen does not contain aspirin. These are two different drugs which belong to the same group of medicines called non-steroidal anti-inflammatory drugs (NSAIDs).

Q.

Does naproxen get you high?
Naproxen does not get you high. It has not been reported to have any addiction potential.

Q.

Does naproxen work?
Naproxen works if used for the right indication at prescribed doses for the prescribed duration as advised by your doctor.

Q.

Does naproxen have paracetamol in it?
Naproxen does not contain paracetamol. These are two different medicines which belong to the same group of medicines called non-steroidal anti-inflammatory drugs (NSAIDs).

Q.

Can I take naproxen for the treatment of flu?
Naproxen is not recommended for the treatment of flu. Talk to your doctor if you have flu before taking any medicines. It is a self-limiting condition and you may not need to take any treatment for this.

Q.

Can I take naproxen for swollen glands?
Naproxen may be given to reduce the pain and swelling associated with the swollen glands. It does not, however, treat any underlying infections if any, you would need antibiotics for the same. Consult a doctor before taking any antibiotics.

Esomeprazole

Q.

Is esomeprazole available over the counter?
No, esomeprazole is not available as an over-the-counter medication. It is a prescription medicine and is available only when prescribed by a physician.

Q.

Can I take esomeprazole with aluminium hydroxide and magnesium carbonate or other antacids?
There is no reported interaction between esomeprazole and antacids. However, antacids increase the pH of the stomach and esomeprazole requires a lower pH for its action and hence there could be a decreased action of esomeprazole if taken with antacids. This interaction can be avoided by taking antacids two hours before or one hour after taking esomeprazole.

Q.

Does esomeprazole contain lactose?
Many esomeprazole preparations contain lactose and sucrose. Lactose intolerance has been reported with its use in some patients who cannot digest lactose, a type of sugar mainly found in milk and dairy products. The patient may complain of symptoms like flatulence (gas), diarrhea, bloating, stomach pain and feeling of being sick (nausea). Read the ingredients mentioned on the pack before taking the medicine.

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Q.

Is esomeprazole a controlled substance?
Esomeprazole is not a controlled substance. It is available when prescribed by a doctor.

Q.

Is esomeprazole safe?
Yes, esomeprazole is safe if taken for prescribed duration in prescribed doses as advised by your doctor.

Q.

Does esomeprazole cause weight loss?
Tell your doctor if you experience weight loss with esomeprazole as it may cause damage to your stomach lining on a long term use and weight loss could be an indication of the same.

Q.

Does esomeprazole cause hair loss?
Hair loss has been reported as a rare side effect of esomeprazole. Please consult your doctor in case you experience excessive hair fall while you are taking esomeprazole.

Q.

Why is esomeprazole better than omeprazole?
Esomeprazole is the S-isomer of omeprazole. Isomers are compounds which have the same molecular formula but different chemical structures. Studies have shown that esomeprazole provides more effective acid control than omeprazole, without any increase in side effects. Furthermore, esomeprazole has a rapid onset of action than omeprazole and less inter-individual variation in acid control.

Q.

Does esomeprazole cause palpitations (feeling of rapid, strong heart beat)?
Esomeprazole can lower the magnesium levels in your body and this can cause palpitations. You must get your magnesium levels checked regularly if you are asked to use this medicine for more than three months.

Q.

Can a patient undergoing dialysis take esomeprazole?
Esomeprazole can be taken by a patient undergoing dialysis in a manner as prescribed by the doctor. Since esomeprazole is extensively protein bound, it is not expected to be removed by dialysis.

Q.

Can esomeprazole be given in the pediatric age group?
The safety and effectiveness of esomeprazole have been established in pediatric patients 1 to 17 years of age for short-term treatment (up to eight weeks) of Gastroesophageal Reflux Disease (GERD). The safety and effectiveness of esomeprazole have been established in pediatric patients 1 month to less than 1 year for short-term treatment (up to 6 weeks) of erosive esophagitis due to acid-mediated GERD. However, the safety and effectiveness of esomeprazole have not been established in patients less than 1 month of age.

Q.

Is esomeprazole better than rabeprazole?
The superiority of either esomeprazole or rabeprazole over the other is not clearly defined. One study mentions that rabeprazole (40 mg) is a better choice for mild-to-moderate Gastroesophageal Reflux Disease (GERD) compared with esomeprazole (40 mg) because of its better efficacy and safety profile. Another study mentions that esomeprazole 40 mg provides a more effective and faster acid-inhibitory effect than rabeprazole 20 mg. Also, there are studies which mention that esomeprazole and rabeprazole both are better than the other medicines of the same class (i.e proton pump inhibitors).

Q.

Is esomeprazole better than ranitidine?
Esomeprazole is a proton pump inhibitor (PPI). It lowers the amount of acid in your stomach, treats heartburn, and heals ulcers. Ranitidine is an H2 blocker. It blocks the chemical histamine, which lowers acid production in your stomach. This treats heartburn and helps ulcers heal. There are not many studies which compare esomeprazole with ranitidine. However, one study mentions that esomeprazole 40 and 20 mg once daily are effective and well-tolerated therapies compared with ranitidine 150 mg twice daily for healing gastric ulcers.

Q.

Can I take esomeprazole with domperidone?
Domperidone is an anti-emetic which can stop you feeling sick. There are no reported drug interactions or harmful effects of using esomeprazole with domperidone. Domperidone can be taken with esomeprazole. Esomeprazole is also available in combination with domperidone.

Q.

Can I take esomeprazole with clopidogrel?
Esomeprazole decreases effects of clopidogrel by affecting the metabolism of clopidogrel. Avoid using both drugs together or use an alternate drug.

Q.

Can I take esomeprazole with levosulpiride?
Esomeprazole can be taken with levosulpiride. Esomeprazole decreases the acid secretion and levosulpiride increases the intestinal motility. It is safe to use the two medicines together. Esomeprazole is also available as a fixed-dose combination with levosulpiride. This combination helps in the treatment of heartburn, stomach and duodenal ulcers and gastritis.

Q.

Is esomeprazole an antacid?
Esomeprazole belongs to the class of proton pump inhibitors (PPIs) which decrease the amount of acid produced in the stomach. It is not an antacid as it does not neutralize the stomach acid by coating the stomach.

Q.

Is esomeprazole better than omeprazole or lansoprazole or pantoprazole?
Esomeprazole, omeprazole, lansoprazole and pantoprazole belongs to the same class of medicines with similar action, but their effect may vary upon individual response. Always follow doctor's advice regarding its use.

Q.

Can I take esomeprazole with paracetamol (acetaminophen)?
It is safe to take esomeprazole with paracetamol (acetaminophen) as no drug-drug interactions have been reported. However, this does not mean that no interactions exist. Please consult your doctor while taking the two medicines together.

Q.

Does esomeprazole cause tinnitus?
Tinnitus has been reported as a rare side effect with esomeprazole (<1% patients taking esomeprazole). Please consult your doctor if you experience tinnitus while taking esomeprazole.

Q.

Does esomeprazole has an expiry date?
Yes, esomeprazole does expire. Please check the expiry date written on the pack and it refers to the last day of that month. Do not use esomeprazole after the expiry date.

Q.

Is esomeprazole an antibiotic?
No, esomeprazole is not an antibiotic.

Q.

Can I take esomeprazole with nitrofurantoin?
Esomeprazole can be taken with nitrofurantoin. No drug-drug interactions have been reported between the two. However, this does not mean that interactions cannot occur. Please consult your doctor before taking the two medicines together.

Q.

Can I take esomeprazole with ranitidine?
Yes, esomeprazole can be taken with ranitidine. No drug-drug interactions have been seen between the two. However, this does not mean that interactions cannot occur. Please consult your doctor before taking the two medicines together.

Q.

Can I take esomeprazole with ibuprofen?
Esomeprazole can be taken with ibuprofen. No drug-drug interactions have been reported between the two. However, this does not mean that interactions cannot occur. Please consult your doctor before taking the two medicines together.

Q.

Can I take esomeprazole with hyoscine?
Esomeprazole can be taken with hyoscine. No drug-drug interactions have been reported between the two. However, this does not mean that interactions cannot occur. Please consult your doctor before taking the two medicines together.

Q.

Can I take esomeprazole with food?
Esomeprazole should preferably be taken one hour before meals.

Q.

Does esomeprazole cause tiredness?
Tiredness is a rare side effect of esomeprazole. Please consult your doctor if you experience excessive tiredness as this may be due to underlying liver abnormalities as esomeprazole breaks down in the liver.

Q.

Does esomeprazole cause weight gain?
Weight gain has not be reported to occur with esomeprazole.

Q.

Does esomeprazole affect birth control?
Esomeprazole does not seem to affect birth control, as no drug interactions have been reported between esomeprazole and oral birth control pills. It is safe to take the two medications together.

Q.

Why is esomeprazole enteric coated?
Esomeprazole is enteric coated to avoid its breakdown by stomach acids and it can reach the intestine and gets absorbed there. Also, the enteric-coated tablets should not be broken or crushed before swallowing.

Q.

Can a patient with underlying cardiac disease take esomeprazole?
Patients with the underlying cardiac disease can take esomeprazole. However, esomeprazole can interact with certain drugs (e.g clopidogrel, digoxin) which might be used by a patient with the underlying cardiac disease. Patients taking esomeprazole and digoxin may need to be monitored for digoxin toxicity. Esomeprazole decreases the activation of clopidogrel, thus reducing its effects. Patients taking these medicines together needs to be monitored regularly.

Q.

Can esomeprazole be given in cancer patients?
Esomeprazole can be taken by cancer patients in a manner as prescribed by the doctor. There are certain studies which have shown that esomeprazole enhanced the antitumor effect of chemotherapy medicines with no added side effects. However, esomeprazole has not been approved for this condition yet. Since cancer patients may also take many other medicines for the primary cancer treatment or for other symptoms and infections, there are chances of drug interactions with esomeprazole. The use of esomeprazole with other drugs should be monitored.

Q.

How much time does esomeprazole take to show its effect?
The onset of action of esomeprazole is within 3 hours and lasts for a duration of up to 24 hours.

Q.

How is esomeprazole different from pantoprazole?
Esomeprazole and pantoprazole are found to be equally effective in the treatment of Gastroesophageal Reflux Disease (GERD). One study mentions treatment with pantoprazole resulted in significantly faster first-time relief from daytime and night-time GERD-related symptoms than esomeprazole.

Q.

Is esomeprazole more effective than lansoprazole?
Yes, esomeprazole is seen to achieve a better acid control and being more effective in rapid relief of heartburn symptoms and acid reflux symptoms as compared to lansoprazole in many research studies. Also, healing rates were consistently high with esomeprazole.

Q.

Can I take esomeprazole with sodium bicarbonate as a buffer?
Sodium bicarbonate buffer protects against acid degradation of esomeprazole in addition to immediate antacid action. Esomeprazole can be taken with sodium bicarbonate as a buffer only in a manner as prescribed by the doctor.

Q.

Can I take esomeprazole with naproxen?
Naproxen is a nonsteroidal anti-inflammatory drug (NSAID) which works by reducing inflammation and pain in the body. There are no reported drug interactions or harmful effects of using esomeprazole with naproxen. Esomeprazole and naproxen can be taken together.

Q.

Is esomeprazole a narcotic?
Esomeprazole is not a narcotic. It belongs to the class of proton pump inhibitors.

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Content on this page was last updated on 19 April, 2017, by Dr. Varun Gupta (MD Pharmacology)