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Esonap Tablet DR

Written By Dr. Swati Mishra, BDS
Reviewed By Dr. Rajeev Sharma, MBA, MBBS
Last updated on 21 Sep 2025 | 05:35 PM (IST)
Esonap Tablet DR is a combination medicine which helps in relieving pain. It is used to relieve pain and inflammation in conditions like rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis. It is also used to relieve muscle pain, back pain, toothache, or pain in the ear and throat.
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General Information

Contains

Naproxen (500mg)+ Esomeprazole (20mg)

Marketer

Bioceutics Inc

Storage

Store below 25°C
The content is shown in English
Esonap Tablet DR image
Esonap Tablet DR image
Esonap Tablet DR image

Product introduction

Esonap Tablet DR should be taken with food. This will prevent you from getting an upset stomach. The dose will depend on what you are taking it for and how well it helps your symptoms. You should take it as advised by your doctor. Do not take more or use it for longer duration than recommended by the doctor.

The most common side effects of this medicine include headache, nausea, vomiting, diarrhea, indigestion, flatulence, and stomach pain. If any of these side effects bother you or get worse, you should speak to your doctor. Your doctor may be able to suggest ways of preventing or reducing the side effects.

Before taking it, you should let your doctor know if you have a history of ulcer or bleeding in your stomach, high blood pressure, or have any trouble with your heart, kidneys, or liver. Let your doctor also know about all the other medicines you are taking because they may affect, or be affected by, this medicine.

Pregnant or breastfeeding women should consult their doctor before starting treatment. You should also avoid drinking alcohol while you are taking this medicine, as alcohol can cause excessive drowsiness.

Uses of Esonap Tablet DR

Benefits of Esonap Tablet DR

Pain relief
Esonap Tablet DR relieves pain, reduce swelling and ease inflammation in conditions like rheumatoid arthritis and osteoarthritis. It also gives relief from muscle and back pain, toothache, or pain in the ear and throat. It works by reducing substances in the body that cause pain and swelling. Esonap Tablet DR contains an antacid which prevents acidity that might have occur due to this medicine.

Side effects of Esonap Tablet DR

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Esonap
  • Headache
  • Nausea
  • Vomiting
  • Diarrhea
  • Indigestion
  • Flatulence
  • Stomach pain
  • Flu-like symptoms

How to use Esonap Tablet DR

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Esonap Tablet DR is to be taken with food.

How Esonap Tablet DR works

Esonap Tablet DR is a combination of two medicines: Naproxen and Esomeprazole which relieve pain. Naproxen is a non-steroidal anti-inflammatory drug (NSAID) which works by blocking the release of certain chemical messengers that cause fever, pain and inflammation (redness and swelling). Esomeprazole is a proton-pump inhibitor.which reduces the amount of acid in the stomach and prevents damage to the stomach lining caused by Naproxen.

Quick tips

  • Esonap Tablet DR is used to treat various painful conditions.
  • Take it with a glass of milk in order to prevent side effects such as indigestion.
  • If you have asthma, symptoms such as wheeze or breathlessness might get worse Esonap Tablet DR. In such a case see your doctor right away.
  • Inform your doctor if you have or ever had ulcers in your stomach or intestines.
  • Inform your doctor if you are planning to have an operation (even a minor one, such as tooth extraction) since Esonap Tablet DR increases the risk of bleeding.

Safety advice

Alcohol

Alcohol

UNSAFE
It is unsafe to consume alcohol with Esonap Tablet DR.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Esonap Tablet DR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding

Breast feeding

SAFE IF PRESCRIBED
Esonap Tablet DR is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Driving

Driving

UNSAFE
Esonap Tablet DR may cause side effects which could affect your ability to drive.
Esonap Tablet DR may make you feel dizzy, depressed, sleepy, tired, or make it difficult to sleep. It may also affect your vision. This may affect your driving ability.
Kidney

Kidney

CAUTION
Esonap Tablet DR should be used with caution in patients with kidney disease. Dose adjustment of Esonap Tablet DR may be needed. Please consult your doctor.
Liver

Liver

CAUTION
Esonap Tablet DR should be used with caution in patients with liver disease. Dose adjustment of Esonap Tablet DR may be needed. Please consult your doctor.

Frequently asked questions

Esonap Tablet DR is used to relieve pain and inflammation in conditions like arthritis. Naproxen in Esonap Tablet DR helps relieve pain, and esomeprazole in Esonap Tablet DR helps protect the stomach lining from ulcers that naproxen alone might cause.
Individuals should not take Esonap Tablet DR if they are allergic to naproxen, esomeprazole, aspirin, or other NSAIDs, or if they have had asthma, hives, or serious allergic reactions after using pain relievers. It should not be used by people with a history of stomach bleeding caused by NSAIDs.
Yes, naproxen in Esonap Tablet DR may increase the risk of serious heart conditions such as heart attack or stroke, especially with long-term use or in people with existing heart disease.
Before using Esonap Tablet DR, tell your doctor if you have high blood pressure, high cholesterol, diabetes, heart disease, kidney disease, liver disease, or if you smoke. These conditions may increase your risk of serious side effects.
Yes, naproxen in Esonap Tablet DR can cause stomach ulcers and bleeding. The esomeprazole in Esonap Tablet DR helps reduce this risk, but it does not completely prevent it. Watch for warning signs like black stools, vomiting blood, or severe stomach pain.
Serious side effects of Esonap Tablet DR include heart attack, stroke, kidney failure, liver injury, severe allergic reactions, and bleeding in the stomach or intestines. Get immediate medical help if you notice chest pain, shortness of breath, sudden weakness, or yellowing of the skin.
Stop taking Esonap Tablet DR and call your doctor if you develop chest pain, sudden weakness, shortness of breath, black stools, vomiting blood, unexplained weight gain, swelling of the body, or severe skin reactions.
Long-term use of Esonap Tablet DR can increase the risk of serious heart, kidney, and stomach problems. Doctors usually prescribe the lowest effective dose for the shortest time needed to reduce risks.

Fact Box

Habit Forming

No

Therapeutic Class

PAIN ANALGESICS

References

  1. Naproxen. Nutley, New Jersey: Roche Laboratories Inc. [Accessed 02 Apr. 2019] (online) Available from:
  2. ScienceDirect. Naproxen. [Accessed 23 Apr. 2019] (online) Available from:
  3. Esomeprazole. Wilmington, Delaware: AstraZeneca Pharmaceuticals; 1989 [revised Dec. 2014]. [Accessed 28 Mar. 2019] (online) Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Bioceutics Inc
Address: No. 15, Plot no. 92B, 6th Cross Street, Senthil Nagar, Kolathur Chennai – 600 099

Vendor Details

Country of origin: India

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