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Last updated:
18 Feb 2020 | 05:25 PM (IST)
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Equirab 1500 Injection

Prescription Required

Overview

Introduction

Equirab 1500 Injection is derived from the blood of horses. eRIG neutralize the virus at the wound site within a few hours. There are two types of Rabies Immunoglobulin, human (hRIG) and equine (eRIG). Both have similar clinical effectiveness in eliminating the virus at the wound site.

Equirab 1500 Injection is given as an injection by a doctor or nurse. It provides immunization and is indicated in individuals with category III exposures (in depth injury). RIG neutralizes the rabies virus at the inoculation site on time before the immune system responds to the vaccine by production of rabies virus neutralizing antibodies. Both active (vaccine) and passive immunization (Immunoglobulin) prevent the rabies virus from infiltrating the central nervous system, but become ineffective once the virus has crossed into the central nervous system. Equirab 1500 Injection is administered only once in a lifetime. RIG administration is not indicated 7 days after the initial rabies vaccine administration.

The most common side effects include nausea, acute toxicity, rash, and stomach upset. They do not normally last very long. Sitting or lying down can sometimes help. Consult your doctor if any of the side effects persist or worry you.

Before having the injection, you should tell your doctor if you’ve ever had an allergic reaction to a immunoglobulin. Some other medicines may react with the equine rabies immunoglobulin so talk to your doctor about other medications you are taking as well. You should consult your doctor first if you are pregnant or breastfeeding.

Uses of Equirab Injection

Side effects of Equirab Injection

Common
  • Nausea
  • Acute toxicity
  • Rash
  • Upset stomach

How to cope with side effects?

The occurrence of side effects varies from person to person. The following are a few ways of dealing with some of the common side effects. However, consult your doctor if these persist.

  • Coping with Nausea
    You can help yourself by eating small, frequent meals rather than large ones and drinking plenty of fluids. Eat slowly. Avoid fatty, fried, spicy and very sweet foods. Eat cold or slightly warm food if the smell of cooked or cooking food makes you feel sick. Get plenty of fresh air. You could also try chewing ginger or drinking ginger tea. Eat bananas to replace potassium in your blood which can drop if you are sick (vomit). Use oral rehydration salts to replace vitamins and minerals lost through being sick. There are some medicines that can help you stop from feeling sick. Speak to your doctor if your condition does not improve.
  • Coping with Rash
    There are many treatments for a wide range of skin problems. Avoid hot showers or baths because hot water can irritate the skin. Make sure to pat dry your skin after a bath or shower. Do not rub or scratch the affected area. Leave the skin exposed to the air as much as possible. Do not use perfumed soaps or deodorants. Water containing chlorine can make most skin problems worse, so avoid swimming. Avoid spicy foods, alcohol, tobacco smoke and caffeine as it may also make itching worse. Avoid excessive sun exposure. Always use sunscreen and protective clothing when outdoors. Moisturizers can be used regularly to soothe and hydrate the affected area. If it does not get better within a week, speak to a pharmacist or doctor.
  • Coping with Upset stomach
    Try taking your medicine with a meal or snack, or shortly after eating. It might help to eat smaller and more frequent meals, and to eat and drink slowly. Avoid foods which can irritate your stomach such as carbonated soft drinks, caffeine, fatty and spicy foods, mints and citrus fruits. Quit smoking and alcohol because they increase the symptoms. Do not eat for 3 or 4 hours before going to bed. Try raising the head of your bed at night or use extra pillows. Ask your doctor or pharmacist about medicines that may help, such as antacids, if your condition does not improve.

How to use Equirab Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Equirab Injection works

Equirab 1500 Injection is an inactivated vaccine (made from a dead virus). It helps develop immunity by forming antibodies, which are proteins that protect against infection caused by viruses present in the vaccine.

Safety Advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Equirab 1500 Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Information regarding the use of Equirab 1500 Injection during pregnancy is not available. Please consult your doctor.
Breastfeeding
CONSULT YOUR DOCTOR
Information regarding the use of Equirab 1500 Injection during breastfeeding is not available. Please consult your doctor.
Driving
CONSULT YOUR DOCTOR
It is not known whether Equirab 1500 Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
SAFE IF PRESCRIBED
Equirab 1500 Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Equirab 1500 Injection may not be needed in these patients. Please consult your doctor.
Liver
SAFE IF PRESCRIBED
Equirab 1500 Injection is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Equirab 1500 Injection may not be needed in these patients. Please consult your doctor.

What if you forget to take Equirab Injection?

If you miss a dose of Equirab 1500 Injection, please consult your doctor.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
No alternate brands found for this medicine

Interaction with Drugs

Taking Equirab with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Healgraft, Graftidem, Mycocel S
LIFE-THREATENING
Brand(s): Thioprinz, Lazorin, Azarid
SERIOUS
Brand(s): Oncomide, Cyclomet, Cyphos
SERIOUS
Brand(s): Empurine
SERIOUS

Patient Concerns

arrow
I'm having several warts on face n neck. What will be the cost of RF procedure to remove the same?
Dr. Souvik Sardar
Dermatology
It varies 1500 to 4000
My son is on course of rabies injections named rabipur by Novartis . His last injection is due but now the injection is not available in the market. Can we give a substitute inj zoonovac by Bharat serums as a last dose
Dr. Monil Kadian
Cardiology
If possible continue with rabipur otherwise you can take the other one also
arrow
Do you have any questions related to Equirab 1500 Injection ?

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Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Chawan VS, Tripathi RK, Sankhe L, et al. Safety of equine rabies immunoglobulin in grade III bites. Indian J Community Med. 2007;32(1):73-74. [Accessed 04 Apr. 2019] (online) Available from:External Link
  2. Wilde H, Chutivongse S. Equine rabies immune globulin: a product with an undeserved poor reputation. Am J Trop Med Hyg. 1990;42(2):175-8. [Accessed 04 Apr. 2019] (online) Available from:External Link
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