EP-CD Cream

Reviewed By Dr. Mekhala Chandra, MD, MBBS

Last updated on 30 Dec 2025 | 12:54 AM (IST)

EP-CD Cream is a medicine used in the treatment of anal fissure (tear in the lining of the anus). It helps reduce pain, burning, and swelling. It also protects from infection and promotes the healing of fissures.

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₹99.3 MRP ₹112.512% off

EP-CD Cream is currently sold out

Same composition alternative:

Crema-Ano Rectal Cream

₹151~~₹173.6~~

Available alternative from Abbott

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EP-CD Cream

tube of 20 gm Rectal Cream

₹99.3

~~₹112.5~~

Same composition

Crema-Ano Rectal Cream

tube of 20 gm Rectal Cream

Lidocaine (4% w/w) + Metronidazole (1% w/w) + Sucralfate (7% w/w)

by Abbott

Get in 60 mins

₹151

₹6.4 per gm

₹128

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₹1200

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General Information

Contains

Lidocaine (4% w/w)+ Metronidazole (1% w/w)+ Sucralfate (7% w/w)

Marketer

Dvm Life Sciences Pvt Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Additionally, EP-CD Cream forms a protective coating on the affected area and prevents any irritation, pain, or burning sensation in the anus. This promotes wound healing and protects the affected area from further injury.

EP-CD Cream should be used in the dose and duration as directed by your doctor. Clean and dry the affected area, and gently apply it over the affected area. Make sure to wash your hands thoroughly before and after applying this medicine. Do not stop using it suddenly without talking to your doctor, as it may lead to worsening your condition.

Avoid getting it into your eyes, nose, or mouth. In case of accidental exposure, wash them with plenty of water and seek medical attention. You should stop using it and inform your doctor if you notice worsening of the infection or if you develop increased redness and irritation.

On application, the medicine may cause burning sensations, tingling, and rashes. However, these are temporary and usually resolve with time. If you experience any other side effects that you think are caused by the medicine, you should let your doctor know. They may be able to suggest ways to reduce or prevent the side effects.

To make sure it is safe for you, always tell your doctor what other health conditions you have and what other medicines you are taking. If you are pregnant, thinking about becoming pregnant, or breastfeeding, ask your doctor before taking this medicine.

Uses of EP-CD Rectal Cream

Treatment of Anal fissure

Benefits of EP-CD Rectal Cream

Treatment of Anal fissure
Anal fissure is a small tear in the lining of the anus that may occur when you pass hard or large stools. Anal fissures typically cause pain while passing stools. EP-CD Cream has a numbing agent that decreases pain sensation in the affected area and helps in passing the stools easily. It also has an antibiotic property and prevents any infections in the anal area. Applying EP-CD Cream gives relief from pain, swelling, irritation, itching, or burning sensation caused by an anal fissure. It promotes healing and helps with faster recovery. Make sure to avoid spicy, oil-rich food and take plenty of fiber to aid in digestion and ensure speedy recovery.

Side effects of EP-CD Rectal Cream

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of EP-CD

Burning sensation
Tingling
Rash

How to use EP-CD Rectal Cream

This medicine is for external use only. Use it in the dose and duration as advised by your doctor.

How EP-CD Rectal Cream works

EP-CD Cream is a combination of three active ingredients: metronidazole, lidocaine, and sucralfate. Metronidazole is a potent anaerobic antibacterial agent that eliminates infection-causing bacteria and helps prevent the spread of infection. Lidocaine is a local anesthetic that blocks pain signals from the nerves to the brain, providing quick relief from pain, burning, and discomfort. Sucralfate is a cytoprotective agent that forms a protective barrier over the affected area, aiding in ulcer healing and promoting faster recovery of damaged tissue. Together, these ingredients relieve pain, reduce infection, and support the natural healing of the anal mucosa.

All substitutes for EP-CD Cream

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

EP-CD Cream is prescribed to relieve pain, swelling, and other discomfort in the rectal area caused by fissures.
In addition to using EP-CD Cream, you may take warm sitz baths, which can help soothe the area and ease pain.
Do not ignore the urge to defecate. Delaying bowel movements can lead to the formation of harder, larger stools that are more difficult and painful to pass.
Avoid taking any oral laxatives along with EP-CD Cream unless advised by your doctor.
Some medicines, such as iron supplements or certain antibiotics, can make stools harder to pass. Inform your doctor if you are taking any of these.
A fiber-rich diet (including wholegrain bread, cereals, fruits, and green leafy vegetables), adequate hydration with six to eight glasses of water daily, and regular physical activity are essential for maintaining healthy bowel movements and preventing constipation.

Safety advice

Alcohol

No interaction found/established

Pregnancy

CONSULT YOUR DOCTOR

Information regarding the use of EP-CD Cream during pregnancy is not available. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of EP-CD Cream during breastfeeding is not available. Please consult your doctor.

Driving

No interaction found/established

Kidney

CONSULT YOUR DOCTOR

There is limited data available on the use of EP-CD Cream in patients with kidney disease. Please consult your doctor.

Liver

CONSULT YOUR DOCTOR

There is limited data available on the use of EP-CD Cream in patients with liver disease.

Frequently asked questions

What is EP-CD Cream used for?

EP-CD Cream is used to treat anal fissures (small tears in the lining of the anus). It works by killing infection-causing bacteria, promoting healing, and blocking pain signals to reduce discomfort. Additionally, it forms a protective layer over the affected area, helping to prevent irritation, pain, and burning, while supporting faster healing and protecting the area from further damage.

Can I use EP-CD Cream for hemorrhoids with itching and bleeding?

Yes, EP-CD Cream helps soothe itching, reduce swelling, and control minor bleeding associated with hemorrhoids.

How should I apply EP-CD Cream for best results?

Clean the affected area gently, then apply a thin layer of EP-CD Cream inside the rectum and around the anus, usually after bowel movements and before bedtime, as directed by your doctor.

Will EP-CD Cream cause numbness or tingling?

Yes, EP-CD Cream can cause numbness, which is usually temporary. If numbness or tingling persists or worsens, consult your doctor.

How quickly will I feel relief after applying EP-CD Cream?

The exact time EP-CD Cream takes to provide relief is not known. However, most people notice reduced pain and discomfort within minutes to an hour after application.

Fact Box

Habit Forming

Therapeutic Class

GASTRO INTESTINAL

References

Madsen JR, Laursen LS, Lauritsen K. Kronisk inflammatorisk tarmsygdom [Chronic inflammatory bowel disease]. Nord Med. 1992;107(10):254-60. [Accessed 29 Dec. 2025]. Available from:

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Dvm Life Sciences Pvt Ltd
Address: 111-A Rampuram Kanpur Kanpur Up 208013 India

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

EP-CD Cream

Save more with additional offers

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of EP-CD Rectal Cream

Benefits of EP-CD Rectal Cream

Side effects of EP-CD Rectal Cream

How to use EP-CD Rectal Cream

How EP-CD Rectal Cream works

All substitutes for EP-CD Cream

Sucral Ano Cream

Sufrate LA Cream

Surect Cream

ANO-metrogyl Cream

Crema-Ano Rectal Cream

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

What is EP-CD Cream used for?

Can I use EP-CD Cream for hemorrhoids with itching and bleeding?

How should I apply EP-CD Cream for best results?

Will EP-CD Cream cause numbness or tingling?

How quickly will I feel relief after applying EP-CD Cream?

Fact Box

Habit Forming

Therapeutic Class

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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