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Endobloc T Combipack is a combination medicine used in the treatment of pulmonary arterial hypertension (PAH). It works by relaxing the blood vessels inside the lungs.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 13 Apr 2026 | 10:23 AM (IST)
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General Information

The content is shown in English
Endobloc T Combipack image
Endobloc T Combipack image
Endobloc T Combipack image
Endobloc T Combipack image
Endobloc T Combipack image
Endobloc T Combipack image
Endobloc T Combipack image

Product introduction

Endobloc T Combipack can be taken with or without food. You should take it regularly at evenly spaced intervals as per the schedule prescribed by your doctor. Taking it at the same time every day will help you remember to take it. The dose and duration of treatment will depend on what you are being treated for. Do not stop taking it until you have finished the complete course, even when you feel better.

The most common side effects of this medicine include peripheral edema, headache, nasal congestion, cough, anemia, indigestion, and bronchitis. These are usually mild but let your doctor know if they bother you or last more than a few days. It may cause anemia (low number of red blood cells), hence you may be asked for a blood test to check for anemia. You must consult your doctor if the erection persists for more than 4 hours after sexual intercourse while taking this medicine.

Before using it, you should tell your doctor if you have any heart problems or have any kidney or liver problems. You should also let your healthcare team know all other medicines you are taking as they may affect, or be affected by this medicine. Generally, it is advised to avoid alcohol while taking this medicine.

Benefits of Endobloc T Tablet

Treatment of Pulmonary arterial hypertension (PAH)
Pulmonary arterial hypertension can cause shortness of breath, tiredness, dizziness, chest pain and swelling in your ankles and legs. It is caused by thickening of walls of the arteries that supply your lungs making it hard for blood to get through. Endobloc T Combipack relaxes the blood vessels and can help lower the blood pressure in the arteries of your lungs. You will be able to carry out your daily activities more easily and feel less tired or dizzy.

Side effects of Endobloc T Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Endobloc T
  • Chest pain
  • Upper respiratory tract infection
  • Abdominal pain
  • Constipation
  • Headache
  • Bronchitis (inflammation of the airways)
  • Peripheral edema
  • Nasal congestion (stuffy nose)
  • Cough
  • Palpitations
  • Anemia (low number of red blood cells)
  • Indigestion

How to use Endobloc T Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Endobloc T Combipack may be taken with or without food.

How Endobloc T Tablet works

Endobloc T Combipack is a combination of two medicines: Ambrisentan and Tadalafil which treat pulmonary arterial hypertension (high blood pressure in the lungs).

All substitutes for Endobloc T Combipack

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

  • Take it at same time every day to maintain the consistent level of drug in the body.
  • Do not skip any doses and finish the full course of treatment even if you feel better.
  • Your doctor may ask you to get routine blood tests done to check for anemia and to assess the functioning of your liver.
  • Do not drive or do anything requiring concentration until you know how Endobloc T Combipack affects you.
  • Females with reproductive potential should use a reliable form of birth control while using and 1 month after stopping medicine as it is toxic to an unborn baby.
  • Notify your doctor if you are pregnant or planning to conceive or breastfeeding.

Safety advice

Alcohol

Alcohol

CAUTION
Alcohol should be used with caution while taking Endobloc T Combipack.
Pregnancy

Pregnancy

UNSAFE
Endobloc T Combipack is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Information regarding the use of Endobloc T Combipack during breastfeeding is not available. Please consult your doctor.
Driving

Driving

CAUTION
Endobloc T Combipack may cause dizziness or weakness due to changes in blood pressure. Do not drive if these symptoms occur.
Kidney

Kidney

CAUTION
Endobloc T Combipack should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Liver

Liver

UNSAFE
Endobloc T Combipack is unsafe to use in patients with liver disease and should be avoided.

Frequently asked questions

Endobloc T Combipack is used to treat pulmonary arterial hypertension (PAH), a type of high blood pressure in the lungs. It helps improve exercise capacity and reduce related symptoms like breathlessness and fatigue.
People allergic to any ingredient present in Endobloc T Combipack, with severe liver impairment, advanced kidney disease, or those taking nitrates for heart disease, should not use this combination.
Yes, especially when Endobloc T Combipack is combined with alcohol, other blood pressure medicines, or nitrates, it may cause very low blood pressure. Signs include dizziness, fainting, or severe weakness and warrant prompt medical attention.
Women with the potential to become pregnant must use reliable contraception while on Endobloc T Combipack and for 1 month after stopping, as it can harm the unborn baby.
Serious side effects of Endobloc T Combipack may include swelling in your legs or face, unexplained severe headache, chest pain, fast heartbeat, visual disturbances, or difficulty breathing. Seek immediate medical attention if you experience any of these symptoms.

Fact Box

Habit Forming

No

Therapeutic Class

CARDIAC
100% genuine products
100% genuine products
Safe & secure payments
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No contact delivery
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Fully sanitized facilities
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User feedback

Once A Day
100%
Pulmonary arterial hypertension (PAH)
92%
Erectile dysfunction
4%
Others
4%
Excellent
67%
Average
25%
Poor
8%
No Side Effect
56%
Headache
22%
Cough
11%
Peripheral edema
11%
With food
100%
Expensive
71%
Average
21%
Not Expensive
8%
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Cipla Ltd
Address: Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Endobloc T Combipack. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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