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Dutalfa Combipack is a combination of two medicines that work in different ways to treat men with an enlarged prostate gland. It helps to relieve symptoms such as difficulty urinating or needing to go to the toilet more often. It is not used to prevent prostate cancer.

Written By Dr. Syeda Aafia, MBA, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 09 Mar 2026 | 10:46 AM (IST)
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Dutalfa Combipack image
Dutalfa Combipack image
Dutalfa Combipack image

Product introduction

Dutalfa Combipack should be taken immediately after the same meal each day. Take it as a whole, do not break, chew, or crush them. Your doctor will prescribe the dose most suitable for you. To gain the most benefit and treat your symptoms effectively you should not miss doses, even if you feel well. It may take up to 4 weeks to notice an improvement in symptoms but keep taking them regularly. Tell your doctor if your symptoms do not improve after 4 weeks or if they get worse.

The most common side effects of this medicine include decreased libido, inability to get an erection (impotence), and tenderness or enlargement of your breasts. If these effects worry you or do not go away, call your doctor for advice. You may also feel dizzy or drowsy. These risks are higher when you first start taking this drug. Remember, your doctor has given you this medicine because the benefits are greater than the risks of the side effects.

Dutalfa Combipack should not be taken by women or children. Before taking it, tell your doctor if you have low blood pressure or liver or kidney disease. This medicine may not be suitable. It can also affect, or be affected by, other drugs so let your doctor know all other medicines you are taking. You may be advised to wear a condom during sex and to have your blood pressure checked frequently. Talk to your healthcare team if you drink alcohol.

Benefits of Dutalfa Tablet

Treatment of Benign prostatic hyperplasia
When your prostate gland becomes enlarged it can cause urinary problems such as difficulty passing urine and a need to go to the toilet frequently or urgently. It can also cause urine flow to be slower. If not treated, there is a risk that your urine flow will be completely blocked. Dutalfa Combipack is a combination of two medicines that reduces the size of your prostate by blocking the production of a hormone which causes it to grow. Additionally, it relaxes the muscles in the bladder and prostate. Together they can rapidly relieve the symptoms and make it easier for you to urinate. However, it may take up to 6 months to notice the full benefits. Take this medicine exactly as prescribed for maximum benefits.

Side effects of Dutalfa Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Dutalfa
  • Impotence
  • Decreased libido
  • Ejaculation disorder
  • Headache
  • Nausea
  • Abdominal pain
  • Upper respiratory tract infection
  • Breast enlargement in male
  • Breast tenderness in male
  • Dizziness

How to use Dutalfa Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Dutalfa Combipack should be taken with or after food.

How Dutalfa Tablet works

Dutalfa Combipack is a combination of two medicines: Alfuzosin and Dutasteride, which relieves the symptoms of benign prostatic hyperplasia. Alfuzosin is an alpha-blocker. It works by relaxing the muscle around the bladder exit and prostate gland so as to allow easy passage of urine. Dutasteride is a 5-alpha-reductase inhibitor which helps in shrinking the prostate gland by decreasing the level of the hormone which helps the prostate gland grow.

Quick tips

  • You have been prescribed Dutalfa Combipack to relieve the symptoms of benign prostatic hyperplasia (BPH).
  • Take it approximately 30 minutes after the same meal each day.
  • Dutalfa Combipack may cause dizziness or blurring of vision. Do not drive or do anything requiring concentration until you know how it affects you.
  • To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
  • If you are scheduled to undergo an eye surgery due to cataract or glaucoma, inform your eye doctor about the usage of Dutalfa Combipack.
  • It may cause difficulty achieving or maintaining an erection (impotence), decreased sex drive, and ejaculation disorders such as decreased amount of semen produced or decreased sperm count.
  • Do not donate blood for 6 months after taking the last dose of Dutalfa Combipack.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Dutalfa Combipack. Please consult your doctor.
Pregnancy

Pregnancy

UNSAFE
Dutalfa Combipack is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.
Breast feeding

Breast feeding

UNSAFE
Dutalfa Combipack is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving

Driving

CAUTION
Dutalfa Combipack may cause dizziness or weakness due to changes in blood pressure. Do not drive if these symptoms occur.
Kidney

Kidney

CAUTION
Dutalfa Combipack should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Liver

Liver

UNSAFE
Dutalfa Combipack is unsafe to use in patients with liver disease and should be avoided.
Use of Dutalfa Combipack is not recommended in patients with severe liver disease.

Frequently asked questions

No, Dutalfa Combipack does not shrink the size of the prostate. It belongs to the alpha-blocker class of medicines. It helps in relieving symptoms of an enlarged prostate. It works by relaxing the muscles of the bladder and prostate to allow urine to flow more easily.
No, Dutalfa Combipack does not cause erectile dysfunction. On the contrary, it may help in improving any such condition. However, this medicine may cause painful erection (priapism) which does not go away. If priapism is not treated, you may not be able to get an erection in the future.
Dutalfa Combipack should be taken after meals at the same time each day. Do not cut, crush or chew the medicine, but swallow it whole with water.
In very rare cases your liver may be affected and cause liver function abnormality. Hence, it would best to inform the doctor if you already have liver disease before starting the medication. The doctor will prescribe a lower dose of Dutalfa Combipack once or twice daily.
Yes, it can be taken by elderly or old people, but they need to be careful. Regular monitoring is required in case the patient also has high blood pressure. Consult your doctor before taking Dutalfa Combipack.
In rare cases, Dutalfa Combipack may cause abnormal vision. But, it is important to know that this medicine may cause complications during surgery if you are to be operated for cataract. Hence, inform your doctor before surgery that you are taking Dutalfa Combipack. Your doctor may perform surgery differently to prevent any complications.
Extreme care should be taken if you are taking Sildenafil or Vardenafil along with Dutalfa Combipack. The combination may cause a significant decrease in blood pressure which can be serious. Therefore, inform your doctor if you are taking these medicines.
Dutalfa Combipack may lower your blood pressure especially when you suddenly stand up after lying down. You may feel dizzy or fainting and therefore you should get up slowly from bed or chair. This medicine may impair your reactions to certain conditions. Hence, avoid driving or hazardous activities until you know how this medicine will affect you.

Fact Box

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No

Therapeutic Class

UROLOGY
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User feedback

Once A Day
96%
Twice A Day
4%
Benign prostatic hyperplasia
92%
Others
8%
Average
81%
Excellent
19%
No Side Effect
50%
Impotence
17%
Ejaculation disorder
17%
Decreased libido
17%
With food
100%
Expensive
56%
Not Expensive
22%
Average
22%
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Dr Reddy's Laboratories Ltd
Address: Dr. Reddy's Laboratories Ltd., Village Malpur, P.O.Bhud, Baddi, Dist. Solan, H.P.

Vendor Details

Country of origin: India
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