Duotop Tablet is a combination of two medicines used to treat neuropathic pain. It works by protecting the nerve fibres against damage, repairing the damaged nerves. This way it effectively relieves the pain sensation and also elevates the mood.
Duotop Tablet may be taken with or without food. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration advised by your doctor. If you miss a dose of this medicine, take it as soon as you remember. Finish the full course of the treatment even if you feel better. It is important not to stop taking this medicine suddenly.
Some common side effects of this medicine include nausea, constipation, headache, insomnia (difficulty in sleeping), ejaculation disorder, erectile dysfunction, and low sexual desire. However, these are temporary and usually resolve on their own. Please consult your doctor if these do not subside or bother you.
You should avoid alcohol while taking Duotop Tablet, as it may worsen certain side effects. This medicine can also lead to weight gain, eat a healthy balanced diet, avoid snacking with high-calorie food, and exercise regularly. Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts or behavior.
Duotop Tablet is a combination of medicines used to treat long-lasting (chronic) pain caused by nerve damage due to diabetes, shingles, or spinal cord injury. It reduces pain and its associated symptoms such as mood changes, sleep problems, and tiredness. It is thought to work by interfering with pain signals that travel through the damaged nerves and the brain. It also contains nutritional supplements that are essential for improving nerve conduction. Duotop Tablet regularly will improve your physical and social functioning and overall quality of life. It takes a few weeks to work so you need to take it regularly even if you feel it is not doing any good. Once your symptoms have gone you should still keep taking the medicine until your doctor advises you to stop.
Side effects of Duotop Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Duotop
Nausea
Constipation
Headache
Insomnia (difficulty in sleeping)
Ejaculation disorder
Erectile dysfunction
Low sexual desire
How to use Duotop Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Duotop Tablet may be taken with or without food.
How Duotop Tablet works
Duotop Tablet is a combination of two medicines:
Safety advice
Alcohol
UNSAFE
It is unsafe to consume alcohol with Duotop Tablet
Pregnancy
CONSULT YOUR DOCTOR
The safety of Duotop Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding
CONSULT YOUR DOCTOR
Duotop Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving
UNSAFE
Duotop Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
Duotop Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed. Dose adjustment is not recommended in patients with mild and moderate kidney disease.
Liver
UNSAFE
Duotop Tablet is unsafe to use in patients with liver disease and should be avoided.
What if you forget to take Duotop Tablet?
If you miss a dose of Duotop Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine
Quick tips
Duotop Tablet is used to treat certain types of long-lasting pain caused by damage to nerves.
It may ease the pain within a few days but it may take 2-3 weeks before you see maximum benefit.
Inform your doctor if you are taking any other pain-relieving medicines.
Along with taking this medicine, your doctor might advise you to undergo physiotherapy to get relief from pain.
You might experience low sexual desire after taking Duotop Tablet, talk to your doctor if it troubles you.
Fact Box
Habit Forming
No
Therapeutic Class
NEURO CNS
Patient concerns
Most of the times when I get excited or have orgasm I feel pain in my testis and around it .
Dr. Pranay Gandhi
Sexology
hi PATIENT neuropathic pain mostly. take tablet emanzen d 1 bd
Sir Plz suggest me effective pain killer with minimum side effects for back pain and arthritis, which can be taken on regular basis as and when required.
Dr. Vikas Sharma
Neurology
dpeneds on the type of pain - muscular or neuropathic; show tro nearby neuro
Burning sensation in sole ,penile region regularly No spot at penile area but constant burning sensation at sole and penile area No relief from amoxicillin,ceprofloxin doxycyclene Period :last 14 days
Dr. Pranay Gandhi
Sexology
that may be a neuropathic pain. do u have high bp or diabetes. take tablet pregama m 1 od for 15 days
I suffered from brain stroke. How long can I use gabapentin 300 mg tablets ?
Dr. Anshul Varshney
Physician
Hello, Welcome to 1mg. I am Anshul Varshney for your help. This medicine is used to calm down the neuropathic pain. You may take it till you feel better. Later your doctor may reduce the dose and stop it.
I m suffering due to pain in left testis, so I visited pgimer Chandigarh in urology deptt. There I had gone for dopler ultrasound testis and its reports are normal Now whenever I lay down at bed I felt a smaal lump in testis,when I touchdown it, the pain radiates in whole left testis Now I m feeling pain sometimes in both tastis Is it a sign of early vericoseal Or something else Pls. Suggest
Dr. Pranay Gandhi
Sexology
it is a neuropathic pain and it won't show any abnormality in USG. i am worried about the lump u r talking about. its better if u consult a surgeon, PGIMER UROLOGY is the best place to go for examination. if they say its normal, its normal. for pain take pregaba m 1 od
Duotop Tablet is mainly prescribed for treating neuropathic pain (nerve pain), such as that seen in diabetic neuropathy, or other nerve-related issues. Duloxetine in Duotop Tablet is an antidepressant that reduces nerve pain, while methylcobalamin (active vitamin B12) in Duotop Tablet helps restore and protect nerve function.
What precautions should I consider before taking Duotop Tablet?
Before taking Duotop Tablet, tell your doctor if you have a history of liver or kidney disease, glaucoma, mania, or seizures, bleeding disorders, bipolar disorder, or if you drink large amounts of alcohol. Also, mention to your doctor if you are pregnant, breastfeeding, or using other medications.
Who should not use Duotop Tablet?
Individuals should not use Duotop Tablet if they are allergic to duloxetine, methylcobalamin, or any other ingredients present in it. Duotop Tablet must not be taken with medications called monoamine oxidase inhibitors (MAOIs), and it is not recommended for people with severe liver or kidney impairment, or uncontrolled glaucoma (narrow angle).
What are the serious side effects of Duotop Tablet?
Serious side effects of Duotop Tablet include allergic reactions (swelling, rash, trouble breathing), severe skin reactions, liver problems (yellowing of eyes, or skin, dark urine), abnormal mood, or behavior changes (thoughts of self-harm), easy bruising, or signs of serotonin syndrome (agitation, fast heartbeat, hallucinations, muscle stiffness, or vomiting). Seek immediate medical help if you experience any of these symptoms.
Is Duotop Tablet addictive?
No, Duotop Tablet is not habit-forming or addictive when used as prescribed by your doctor.
How long will Duotop Tablet take to show benefits, and how long should I keep taking it?
The exact time Duotop Tablet takes to show benefits is not known. However, relief from nerve pain may begin within a few weeks, but the full effect can take 2 to 4 weeks of regular use. Do not stop taking this medicine suddenly, and always follow your doctor’s advice for starting or stopping Duotop Tablet.
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References
Duloxetine hydrochloride. Basingstoke, Hampshire: Eli Lilly and Company Limited; 2004 [revised 09 Nov. 2018]. [Accessed 23 Apr. 2019] (online) Available from:
MedlinePlus. Vitamin B-12. [Accessed 23 Apr. 2019] (online) Available from:
Gupta JK, Sana QS. Potential Benefits of Methylcobalamin: A Review. Austin J Pharmacol Ther. 2015;3(3):1076. [Accessed 23 Apr. 2019] (online) Available from:
Marketer details
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