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Duobloc 400mg Tablet is a muscle relaxer. It provides relief from the discomfort associated with acute, painful musculoskeletal conditions such as rigidity, tension, stiffness, and muscle spasms.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 05 Aug 2026 | 03:57 PM (IST)
₹65.7 MRP ₹74.5312% off 
 
 
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Duobloc 400mg Tablet image
Duobloc 400mg Tablet image

Product introduction

Duobloc 400mg Tablet should be taken with food. This will prevent you from getting an upset stomach as well as reduce side effects. In general, you should try to use the smallest amount necessary to control your symptoms, for the shortest possible time. You should take this medicine regularly while you need it. Try not to miss doses as this will make the medicine less effective.

Some common side effects of this medicine include sleepiness, dryness in the mouth, stomach upset, vomiting, and nausea. If any of these side effects do not go away or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms.

To make sure it is safe for you, before taking this medicine, let your doctor know if you have any medical conditions or disorders. You should also tell your doctor all the other medicines you are using or taking. Pregnant and breastfeeding women should consult their doctors before using this medicine.

Uses of Duobloc Tablet

  • Muscle relaxation

Benefits of Duobloc Tablet

Muscle relaxation
Duobloc 400mg Tablet is a muscle relaxant that is used to relieve rigidity, inflammation, and swelling in conditions that affect muscles. It works by blocking chemical messengers in the brain that are responsible for such symptoms. It effectively relieves muscle stiffness or spasm, thereby improving muscle movement.
Take Duobloc 400mg Tablet as prescribed by the doctor. The dose and duration will be decided by the doctor depending on the condition you are being treated for. This will help you to go about your daily activities more easily and have a better, more active, quality of life.

Side effects of Duobloc Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Duobloc
  • Sleepiness
  • Dryness in mouth
  • Upset stomach
  • Vomiting
  • Nausea

How to use Duobloc Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Duobloc 400mg Tablet should be taken with or after food.

How Duobloc Tablet works

Duobloc 400mg Tablet is a muscle relaxant. It works on the centres in the brain and spinal cord to relieve muscle stiffness or spasm without reduction in strength. This improves pain and movement of muscles.

Quick tips

  • Duobloc 400mg Tablet provides relief from rigidity, tension and stiffness in muscles (spasticity) that may occur due to various conditions affecting the nervous system.
  • Take it with or after food or a glass of milk.
  • Duobloc 400mg Tablet may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
  • Avoid consuming alcohol when taking Duobloc 400mg Tablet as it may cause excessive drowsiness.
  • Inform your doctor if you are pregnant, planning to conceive or breastfeeding.
  • Do not stop taking it suddenly without talking to your doctor if you've been on it for a long time.
  • Duobloc 400mg Tablet provides relief from rigidity, tension and stiffness in muscles (spasticity) that may occur due to various conditions affecting the nervous system.
  • Take it with or after food or a glass of milk.
  • Duobloc 400mg Tablet may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
  • Avoid consuming alcohol when taking Duobloc 400mg Tablet as it may cause excessive drowsiness.
  • Inform your doctor if you are pregnant, planning to conceive or breastfeeding.
  • Do not stop taking it suddenly without talking to your doctor if you've been on it for a long time.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Duobloc 400mg Tablet. Please consult your doctor.
Pregnancy

Pregnancy

UNSAFE
Duobloc 400mg Tablet is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Information regarding the use of Duobloc 400mg Tablet during breastfeeding is not available. Please consult your doctor.
Driving

Driving

SAFE
Duobloc 400mg Tablet does not usually affect your ability to drive.
Kidney

Kidney

CONSULT YOUR DOCTOR
There is limited data available on the use of Duobloc 400mg Tablet in patients with kidney disease. Please consult your doctor.
Liver

Liver

CONSULT YOUR DOCTOR
There is limited data available on the use of Duobloc 400mg Tablet in patients with liver disease.
All

Fact Box

Chemical Class

Amino pyridine derivative

Habit Forming

No

Therapeutic Class

PAIN ANALGESICS

Action Class

Centrally Acting Skeletal Muscle Relaxants
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Alkem Laboratories Ltd
Address: Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.

Vendor Details

Country of origin: India
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