Duloxtime M 20/750 Tablet

Duloxetine (20mg)+ Methylcobalamin (750mcg)

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Duloxtime M 20/750 Tablet is a combination of two medicines used to treat neuropathic pain. It works by protecting the nerve fibres against damage, repairing the damaged nerves. This way it effectively relieves the pain sensation and also elevates the mood.

Written By Dr. Subita Alagh, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 08 May 2026 | 03:58 PM (IST)

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General Information

Contains

Duloxetine (20mg)+ Methylcobalamin (750mcg)

Marketer

STERIS Healthcare Pvt. Ltd.

Storage

Store below 25°C

The content is shown in English

Product introduction

Duloxtime M 20/750 Tablet may be taken with or without food. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration advised by your doctor. If you miss a dose of this medicine, take it as soon as you remember. Finish the full course of the treatment even if you feel better. It is important not to stop taking this medicine suddenly.

Some common side effects of this medicine include nausea, constipation, headache, insomnia (difficulty in sleeping), ejaculation disorder, erectile dysfunction, and low sexual desire. However, these are temporary and usually resolve on their own. Please consult your doctor if these do not subside or bother you.

You should avoid alcohol while taking Duloxtime M 20/750 Tablet, as it may worsen certain side effects. This medicine can also lead to weight gain, eat a healthy balanced diet, avoid snacking with high-calorie food, and exercise regularly. Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts or behavior.

Uses of Duloxtime M Tablet

Neuropathic pain

Benefits of Duloxtime M Tablet

Neuropathic pain
Duloxtime M 20/750 Tablet is a combination of medicines used to treat long-lasting (chronic) pain caused by nerve damage due to diabetes, shingles, or spinal cord injury. It reduces pain and its associated symptoms such as mood changes, sleep problems, and tiredness. It is thought to work by interfering with pain signals that travel through the damaged nerves and the brain. It also contains nutritional supplements that are essential for improving nerve conduction.
Duloxtime M 20/750 Tablet regularly will improve your physical and social functioning and overall quality of life. It takes a few weeks to work so you need to take it regularly even if you feel it is not doing any good. Once your symptoms have gone you should still keep taking the medicine until your doctor advises you to stop.

Side effects of Duloxtime M Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Duloxtime M

Nausea
Constipation
Headache
Insomnia (difficulty in sleeping)
Ejaculation disorder
Erectile dysfunction
Low sexual desire

How to use Duloxtime M Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Duloxtime M 20/750 Tablet may be taken with or without food.

How Duloxtime M Tablet works

Duloxtime M 20/750 Tablet is a combination of two medicines:

All substitutes for Duloxtime M 20/750 Tablet

For information purposes only. Consult a doctor before taking any medicine.

Sogeval M 20mg/750mcg Tablet

by Druto Laboratories

₹16.1/tablet

28% cheaper

Quick tips

Duloxtime M 20/750 Tablet is used to treat certain types of long-lasting pain caused by damage to nerves.
It may ease the pain within a few days but it may take 2-3 weeks before you see maximum benefit.
Inform your doctor if you are taking any other pain-relieving medicines.
Along with taking this medicine, your doctor might advise you to undergo physiotherapy to get relief from pain.
You might experience low sexual desire after taking Duloxtime M 20/750 Tablet, talk to your doctor if it troubles you.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Duloxtime M 20/750 Tablet

Pregnancy

CONSULT YOUR DOCTOR

Duloxtime M 20/750 Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

CONSULT YOUR DOCTOR

Duloxtime M 20/750 Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

UNSAFE

Duloxtime M 20/750 Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Duloxtime M 20/750 Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Dose adjustment is not recommended in patients with mild and moderate kidney disease.

Liver

UNSAFE

Duloxtime M 20/750 Tablet is unsafe to use in patients with liver disease and should be avoided.

Frequently asked questions

What is Duloxtime M 20/750 Tablet used for?

Duloxtime M 20/750 Tablet is mainly prescribed for treating neuropathic pain (nerve pain), such as that seen in diabetic neuropathy, or other nerve-related issues. Duloxetine in Duloxtime M 20/750 Tablet is an antidepressant that reduces nerve pain, while methylcobalamin (active vitamin B12) in Duloxtime M 20/750 Tablet helps restore and protect nerve function.

What precautions should I consider before taking Duloxtime M 20/750 Tablet?

Before taking Duloxtime M 20/750 Tablet, tell your doctor if you have a history of liver or kidney disease, glaucoma, mania, or seizures, bleeding disorders, bipolar disorder, or if you drink large amounts of alcohol. Also, mention to your doctor if you are pregnant, breastfeeding, or using other medications.

Who should not use Duloxtime M 20/750 Tablet?

Individuals should not use Duloxtime M 20/750 Tablet if they are allergic to duloxetine, methylcobalamin, or any other ingredients present in it. Duloxtime M 20/750 Tablet must not be taken with medications called monoamine oxidase inhibitors (MAOIs), and it is not recommended for people with severe liver or kidney impairment, or uncontrolled glaucoma (narrow angle).

What are the serious side effects of Duloxtime M 20/750 Tablet?

Serious side effects of Duloxtime M 20/750 Tablet include allergic reactions (swelling, rash, trouble breathing), severe skin reactions, liver problems (yellowing of eyes, or skin, dark urine), abnormal mood, or behavior changes (thoughts of self-harm), easy bruising, or signs of serotonin syndrome (agitation, fast heartbeat, hallucinations, muscle stiffness, or vomiting). Seek immediate medical help if you experience any of these symptoms.

Is Duloxtime M 20/750 Tablet addictive?

No, Duloxtime M 20/750 Tablet is not habit-forming or addictive when used as prescribed by your doctor.

How long will Duloxtime M 20/750 Tablet take to show benefits, and how long should I keep taking it?

The exact time Duloxtime M 20/750 Tablet takes to show benefits is not known. However, relief from nerve pain may begin within a few weeks, but the full effect can take 2 to 4 weeks of regular use. Do not stop taking this medicine suddenly, and always follow your doctor’s advice for starting or stopping Duloxtime M 20/750 Tablet.

Fact Box

Habit Forming

Therapeutic Class

NEURO CNS

References

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: STERIS Healthcare Pvt. Ltd.
Address: A.O. Plot No. 41/42, Sector 36, Satykunl CHS LTD, Panvel, Navi Mumbai - 410206

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Duloxtime M 20/750 Tablet

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Duloxtime M Tablet

Benefits of Duloxtime M Tablet

Side effects of Duloxtime M Tablet

How to use Duloxtime M Tablet

How Duloxtime M Tablet works

All substitutes for Duloxtime M 20/750 Tablet

Sogeval M 20mg/750mcg Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

What is Duloxtime M 20/750 Tablet used for?

What precautions should I consider before taking Duloxtime M 20/750 Tablet?

Who should not use Duloxtime M 20/750 Tablet?

What are the serious side effects of Duloxtime M 20/750 Tablet?

Is Duloxtime M 20/750 Tablet addictive?

How long will Duloxtime M 20/750 Tablet take to show benefits, and how long should I keep taking it?

Fact Box

Habit Forming

Therapeutic Class

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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