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Duloxee-P 75 Capsule DR

Pregabalin (75mg)+ Duloxetine (20mg)

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Duloxee-P 75 Capsule DR is used for the treatment of neuropathic pain. It decreases pain by controlling calcium channel activity of the nerve cells. It also increases the level of chemical messengers in the brain that helps maintain mental balance and stop the movement of pain signals in the brain.

Written By Dr. Syeda Aafia, MBA, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 26 Jan 2026 | 01:24 PM (IST)

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General Information

Contains

Pregabalin (75mg)+ Duloxetine (20mg)

Marketer

Talent India

Storage

Store below 30°C

The content is shown in English

Product introduction

Duloxee-P 75 Capsule DR can be taken with or without food. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration advised by your doctor as this is habit forming medicine. If you miss a dose of this medicine, take it as soon as you remember. Finish the full course of the treatment even if you feel better. It is important not to stop taking this medicine suddenly as it may worsen your symptoms.

Some common side effects of this medicine include peripheral edema, nausea, headache, dryness of mouth, difficulty in concentration and blurred vision. It may cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. This medicine may cause weight gain and to control it, you should have a balanced diet and exercise regularly. It is important to inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts.

Before taking this medicine let your doctor know if you suffer from kidney or liver disease. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Uses of Duloxee-P Capsule DR

Neuropathic pain

Benefits of Duloxee-P Capsule DR

Neuropathic pain
Neuropathic pain is a type of long-lasting pain caused by nerve damage or malfunction, leading to sensations like burning, tingling, or shooting pain. Duloxee-P 75 Capsule DR helps relieve nerve-related pain and reduces associated symptoms such as numbness and discomfort. Improving pain control, supports better sleep, mobility, and overall quality of life for people living with chronic nerve pain.

Side effects of Duloxee-P Capsule DR

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Duloxee-P

Nausea
Constipation
Insomnia (difficulty in sleeping)
Sleepiness
Headache
Dizziness
Tiredness
Ejaculation disorder
Erectile dysfunction
Uncoordinated body movements

How to use Duloxee-P Capsule DR

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Duloxee-P 75 Capsule DR may be taken with or without food.

How Duloxee-P Capsule DR works

Duloxee-P 75 Capsule DR is a combination of two medicines: pregabalin and duloxetine. Pregabalin decreases neurotransmitter release, while duloxetine boosts serotonin and norepinephrine levels to modulate pain perception, working together to relieve nerve pain.

All substitutes for Duloxee-P 75 Capsule DR

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Duloxee-P 75 Capsule DR is used for treating nerve pain caused by diabetes, shingles, fibromyalgia, and spinal cord injuries.
You may have to wait for 2 to 4 weeks before it starts working.
It may cause dizziness during the first few weeks. Don't drive or do anything requiring concentration until you know how Duloxee-P 75 Capsule DR affects you.
Avoid consuming alcohol when taking this medicine as it may cause excessive drowsiness and increase the risk of liver damage.
Monitor your blood pressure regularly, especially during the first month of treatment.
It may cause a sensation of restlessness or an inability to sit or stand still, especially when you first start taking it. Inform your doctor if this happens to you.
Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts or behavior.
Do not stop taking the medication suddenly without talking to your doctor.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Duloxee-P 75 Capsule DR

Pregnancy

CONSULT YOUR DOCTOR

Duloxee-P 75 Capsule DR is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

CONSULT YOUR DOCTOR

Duloxee-P 75 Capsule DR may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

UNSAFE

Duloxee-P 75 Capsule DR may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Duloxee-P 75 Capsule DR should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.

Liver

UNSAFE

Duloxee-P 75 Capsule DR is unsafe to use in patients with liver disease and should be avoided.

Frequently asked questions

What is Duloxee-P 75 Capsule DR used for?

Duloxee-P 75 Capsule DR is mainly used to relieve neuropathic pain, such as that caused by diabetes, shingles, spinal injuries, and chronic pain conditions like fibromyalgia. It helps reduce burning, tingling, or electric shock-type pain by calming damaged nerves.

Who should avoid taking Duloxee-P 75 Capsule DR?

People should avoid taking Duloxee-P 75 Capsule DR if they are allergic to any ingredient present in it, have uncontrolled liver or kidney disease, glaucoma, certain heart conditions, or have ever had an allergic reaction to similar medicines.

Can Duloxee-P 75 Capsule DR cause serious side effects?

Although they are rare, serious side effects of Duloxee-P 75 Capsule DR may include mood changes like anxiety or suicidal thoughts, severe drowsiness, blurred vision, facial swelling, unexplained bruising, or allergic reaction. Seek immediate medical attention if you experience any of these symptoms.

Are there any warnings of Duloxee-P 75 Capsule DR for mental health or mood disorders?

Duloxee-P 75 Capsule DR may increase suicidal thoughts, especially in young adults or those with bipolar disorder. Any new or worsening mood or behavior changes should be reported to your doctor at once.

During Duloxee-P 75 Capsule DR treatment, what symptoms mean I need urgent medical help?

During Duloxee-P 75 Capsule DR treatment, seek immediate care for severe allergic reaction, swelling, shortness of breath, chest pain, confusion, or thoughts of self-harm.

Fact Box

Habit Forming

Therapeutic Class

NEURO CNS

References

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Talent India
Address: 1601, Karnavati Estate, GIDC, Phase III, Vatva, Ahmedabad 382445, Gujarat, India.

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Duloxee-P 75 Capsule DR. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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Duloxee-P 75 Capsule DR

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Duloxee-P Capsule DR

Benefits of Duloxee-P Capsule DR

Side effects of Duloxee-P Capsule DR

How to use Duloxee-P Capsule DR

How Duloxee-P Capsule DR works

All substitutes for Duloxee-P 75 Capsule DR

Mahagaba D 75mg/20mg Capsule DR

Maxdulin 75/20 Capsule DR

Pregaba-D 75/20 Capsule DR

Pregabid D 75/20 Capsule DR

Upnuron-D 75/20 Capsule DR

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

What is Duloxee-P 75 Capsule DR used for?

Who should avoid taking Duloxee-P 75 Capsule DR?

Can Duloxee-P 75 Capsule DR cause serious side effects?

Are there any warnings of Duloxee-P 75 Capsule DR for mental health or mood disorders?

During Duloxee-P 75 Capsule DR treatment, what symptoms mean I need urgent medical help?

Fact Box

Habit Forming

Therapeutic Class

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

Related/Popular tests