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Donac Plus Tablet

Written By Dr. Subita Alagh, BDS
Reviewed By Dr. Mekhala Chandra, MD, MBBS
Last updated on 17 Feb 2026 | 01:12 PM (IST)
Donac Plus Tablet is a pain-relieving medicine. It is used to reduce pain and inflammation in conditions like rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis. It may also be used to relieve muscle pain, back pain, toothache, or pain in the ear and throat.
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General Information

The content is shown in English
Donac Plus  Tablet image
Donac Plus  Tablet image

Product introduction

Donac Plus Tablet should be taken with food. This will prevent you from getting an upset stomach. You should take it regularly as advised by your doctor. Do not take more or use it for a longer duration than recommended by your doctor.


There is limited data on the side effects of Donac Plus Tablet. Let your doctor know if you experience any symptoms while taking Donac Plus Tablet. They may be able to suggest ways to treat or manage the side effects.


Before you start Donac Plus Tablet, tell your doctor if you have any medical conditions. Let your doctor also know about all the medications you are taking, as some medicines may interact with Donac Plus Tablet. Pregnant or breastfeeding women should consult their doctor before taking Donac Plus Tablet to ensure safety.

Uses of Donac Plus Tablet

Benefits of Donac Plus Tablet

Pain relief
Donac Plus Tablet is a combination of medicines that is used for short-term relief of pain, inflammation and swelling. It inhibits release of those chemical messengers in the brain that tell us that we have pain. It effectively relieves back pain, earache, throat pain, toothache and pain due to arthritis too.
Take it as it is prescribed to get the most benefit. Do not take more or for longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time. This will help you to go about your daily activities more easily and have a better, more active, quality of life.

Side effects of Donac Plus Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Donac Plus
  • Limited data available

How to use Donac Plus Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Donac Plus Tablet may be taken with or without food.

How Donac Plus Tablet works

Diclofenac works by blocking the production of certain chemicals (prostaglandins) in the body that cause pain, swelling, and inflammation. Paracetamol acts on the brain to reduce the sensation of pain and also helps lower fever. Together, they provide effective relief from pain, inflammation, and fever.

Quick tips

  • You have been prescribed this combination medicine for relieving pain and inflammation.
  • Avoid taking other medicines containing paracetamol or painkillers unless advised by your doctor.
  • Limit or avoid alcohol while taking this medicine to reduce the risk of liver and stomach problems.
  • Inform your doctor if you have a history of stomach ulcers, liver, kidney, or heart disease.
  • Consult your doctor if pain persists or if you notice symptoms such as severe stomach pain, vomiting, or unusual tiredness.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Donac Plus Tablet. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Information regarding the use of Donac Plus Tablet during pregnancy is not available. Please consult your doctor.
Breast feeding

Breast feeding

UNSAFE
Donac Plus Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Donac Plus Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Kidney

Kidney

CONSULT YOUR DOCTOR
There is limited data available on the use of Donac Plus Tablet in patients with kidney disease. Please consult your doctor.
Liver

Liver

CONSULT YOUR DOCTOR
There is limited data available on the use of Donac Plus Tablet in patients with liver disease.

Frequently asked questions

Donac Plus Tablet is a combination of two medicines: Diclofenac and Paracetamol. This medication helps in relieving pain and inflammation. It works by lowering the levels of chemical substances in the body that cause pain and inflammation. Paracetamol / Acetaminophen has an early onset of action which means that it takes very less time to start its action and it helps in relieving the symptoms till diclofenac starts working.
Yes, Donac Plus Tablet is safe for most of the patients. However, in some patients it may cause some unwanted common side effects like nausea, vomiting, stomach pain, heartburn, diarrhea and other uncommon and rare side effects. Inform your doctor if you experience any persistent problem while taking this medication.
Donac Plus Tablet, when used for long-term pain relief, should be continued for as long as advised by your physician. It can be discontinued if you are using it for short-term pain relief.
Yes, the use of Donac Plus Tablet can cause nausea and vomiting. Taking it with milk, food or with antacids can prevent nausea. Avoid taking fatty or fried foods along with this medication. In case of vomiting, drink plenty of water or other fluids by taking small frequent sips. Talk to your doctor if vomiting persists and you notice signs of dehydration, like dark colored and strong-smelling urine and a low frequency of urination. Do not take any other medicine without speaking to your doctor.
Yes, the use of Donac Plus Tablet can cause dizziness (feeling faint, weak, unsteady or lightheaded) in some patients. If you feel dizzy or lightheaded it is better to rest for some time and resume once you feel better.
Yes, the long-term use of Donac Plus Tablet can cause damage to the kidneys. Normal kidneys produce a chemical called prostaglandins that protect them from damage. Use of painkillers lowers the levels of prostaglandins in the body leading to kidney damage on long-term use. Use of painkillers is not recommended in patients with underlying kidney disease.
The use of Donac Plus Tablet is considered to be harmful in patients with known allergy to painkillers (NSAIDs) or any of the components or excipients of this medicine. The use of this medicine should preferably be avoided in patients with a history of stomach ulcers or in patients with active, recurrent stomach ulcer/bleeding. It should also be avoided in patients with the history of heart failure, high blood pressure, and liver or kidney disease.
Yes, Donac Plus Tablet can be taken with Vitamin B-complex preparations. While Donac Plus Tablet helps to relieve pain, Vitamin B-complex can help to correct the vitamin deficiency that might be causing the underlying painful condition.

Fact Box

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PAIN ANALGESICS
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Axon Drugs Pvt Ltd
Address: Plot No.14, Santhosh Nagar, Korattur North, Chennai - 600076., Tamilnadu, India.

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Donac Plus Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945
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